Results 291 to 300 of about 62,541 (346)

Aortic and cardiovascular remodelling after thoracic endovascular aortic repair for blunt traumatic aortic injury in younger patients: A narrative review of physiological and clinical outcomes

Experimental Physiology, EarlyView.
Abstract Blunt traumatic aortic injury (BTAI) is severe, often fatal in younger populations due to high‐energy deceleration mechanisms. Thoracic endovascular aortic repair (TEVAR) has revolutionised BTAI treatment, surpassing the previously standard open surgical repair in mortality and complication rates.
Marco David Bokobza De la Rosa, Matti Jubouri, Thurkga Moothathamby, Mohamed Refaie, Ali Murtada, Idhrees Mohammed, Ian M. Williams, Damian M. Bailey, Mohamad Bashir   +8 more
wiley   +1 more source

EuroSCORE II: Current limitations and physiological gaps in risk stratification

Experimental Physiology, EarlyView.
Abstract Risk stratification remains critical in cardiac surgery, enabling clinicians to predict adverse outcomes and guide perioperative management. The European System for Cardiac Operative Risk Evaluation (EuroSCORE) II, introduced in 2011, incorporates 18 key variables to provide an evidence‐based approach to risk assessment.
Jing Yong Ng, Eu Fon Tan, Marsioleda Kemberi, Eduardo Urgesi, Matti Jubouri, Damian M. Bailey, Mohamad Bashir, Wael I. Awad   +7 more
wiley   +1 more source

Outcomes After Operations for Unicuspid Aortic Valve With or Without Ascending Repair in Adults

, 2015
Yuanjia Zhu, Eric E. Roselli, Jay J. Idrees, Charles M. Wojnarski, Brian P. Griffin, Vidyasagar Kalahasti, Gösta Pettersson, Lars G. Svensson   +7 more
openalex   +1 more source

Advances in cardiac devices and bioelectronics augmented with artificial intelligence

The Journal of Physiology, EarlyView.
Abstract figure legend Interfaces between the human heart, diagnostic bioelectronics, artificial intelligence, and clinical care. From left to right: Human heart and biosensor interface; representative waveforms of common diagnostic bioelectronic sensing modalities.
Charles Stark, Eric Rytkin, Andrei Alexandru Mircea, Igor R. Efimov   +3 more
wiley   +1 more source

Elucidating the cellular determinants of the end‐systolic pressure‐volume relationship of the heart via computational modelling

The Journal of Physiology, EarlyView.
Abstract figure legend Using a multiscale computational model of left ventricular electromechanics, we investigated how sarcomere dynamics influence the end‐systolic pressure‐volume (ESPV) relationship in ejecting beats compared to isovolumetric beats.
Francesco Regazzoni, Corrado Poggesi, Cecilia Ferrantini   +2 more
wiley   +1 more source

Oxytocinergic signalling in the respiratory parafacial region increases the activity of chemosensitive neurons and respiratory output

The Journal of Physiology, EarlyView.
Abstract figure legend Oxytocinergic modulation of breathing in the retrotrapezoid nucleus (RTN). The paraventricular nucleus of the hypothalamus (PVN), which serves as the primary source of oxytocin (Oxt) in the brainstem, projects to the RTN. In vivo, pharmacological (TGOT) or optogenetic activation of oxytocinergic receptors and varicosities within ...
Emmanuel V. Araujo, Phelipe E. Silva, Luiz M. Oliveira, Yingtang Shi, Ana C. Takakura, Daniel K. Mulkey, Thiago S. Moreira   +6 more
wiley   +1 more source

Computational modelling of the impact of anatomical changes on ECGs in left ventricular hypertrophy

The Journal of Physiology, EarlyView.
Abstract figure legend Eccentric and concentric left ventricular hypertrophy distinctly alter 12‐lead ECG signals. Eccentric hypertrophy predominantly increases voltages in the precordial leads, whereas concentric hypertrophy affects voltages across all leads in a variable manner.
Mohammadreza Kariman, Karli Gillette, Matthias A. F. Gsell, Anton J. Prassl, Gernot Plank, Christoph M. Augustin   +5 more
wiley   +1 more source

Acute intermittent hypercapnic hypoxia augments left ventricular contractility

The Journal of Physiology, EarlyView.
Abstract figure legend Twenty‐four healthy adults were studied to determine the effects of an acute session of 40 min of intermittent hypercapnic hypoxia on cardiac performance. Cardiac function was assessed via echocardiography at rest and during graded stages of lower‐body negative pressure before and after the intervention to quantify load ...
Scott F. Thrall, Alex M. Williams, Philip J. Millar, Megan L. Lance, Brooke M. Shafer, Conan L. H. Shing, Jordan D. Bird, Christopher R. West, Glen E. Foster   +8 more
wiley   +1 more source

Haemodynamic‐energetic mechanism of sudden cardiac death in severe aortic stenosis: A modelling study

The Journal of Physiology, EarlyView.
Abstract figure legend A sudden decrease in total peripheral resistance (TPR), as observed during vasovagal syncope, leads to a reduction in aortic systolic pressure (AO pressure) and afterload. In healthy individuals, the consequent decrease in left ventricular systolic pressure (LV pressure) lowers stroke work and myocardial energy expenditure.
Martin Dvoulety, Michal Sitina
wiley   +1 more source

14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses

The Journal of Physiology, EarlyView.
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley   +1 more source