Results 81 to 90 of about 62,541 (346)

Results of matching valve and root repair to aortic valve and root pathology [PDF]

, 2011
ObjectiveFor patients with aortic root pathology and aortic valve regurgitation, aortic valve replacement is problematic because no durable bioprosthesis exists, and mechanical valves require lifetime anticoagulation. This study sought to assess outcomes
Lars G. Svensson, Lillian H. Batizy, Eugene H. Blackstone, A. Marc Gillinov, Michael C. Moon, Richard S. D’Agostino, Edward M. Nadolny, William J. Stewart, Brian P. Griffin, Donald F. Hammer, Richard Grimm, Bruce W. Lytle, Svensson, Svensson, Miller, Karck, Kallenbach, Akins, Zellner, David, Sarsam, David, Svensson, Schafers, Leyh, van Son, Burkhart, Svensson, David, De Paulis, Pethig, Harringer, Frater, Casselman, El Khoury, Hopkins, Wolfe, Banbury, Rubin, Rosenbaum, Blackstone, Drake, Blackstone, Breiman, Silverman, Svensson, Svensson, Pettersson, Svensson, Svensson, Svensson, Miller   +51 more
core   +2 more sources

Repair of the Bicuspid Aortic Valve [PDF]

Operative Techniques in Thoracic and Cardiovascular Surgery, 2017
Repair has become an alternative to replacement for bicuspid aortic valves that require surgery for regurgitation with left ventricular volume overload or aortic aneurysm. Over the past 15 years, improvements have been made regarding assessment of valve configuration and annular stabilization.
Ulrich Schneider, Hans-Joachim Schäfers
openaire   +2 more sources

PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity

Advanced Science, EarlyView.
Knowledge of the remarkable mechanical force sensing and electrically transducing PIEZO1 and PIEZO2 channels is discussed across vascular biology and its cell types from the embryonic to adult stages in health, disease and old age. How the channels work, relate to other factors and signal for tissue responses to mechanical forces is debated.
David J Beech
wiley   +1 more source

Contemporary Valvular Mechanisms of Aortic Regurgitation in Tricuspid Aortic Valves: Importance in Repair Versus Replacement Strategy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background This study was performed to determine cusp causes of aortic regurgitation in patients with tricuspid aortic valves without significant aortic dilatation and define cusp pathologies amenable to surgical repair (aortic valve repair [AVr]) versus
Saifalislam Almaghrabi, Hector Michelena, Matija Jelenc, Karen B. Abeln, Tristan Ehrlich, Hans‐Joachim Schäfers   +5 more
doaj   +1 more source

Isolated supravalvular aortic stenosis with left ventricular diverticulum and cleft mitral valve: Surgical repair in adulthood

Journal of the Saudi Heart Association, 2017
Supravalvular aortic stenosis is an uncommon but well characterized congenital narrowing of the ascending aorta above the level of the coronary arteries.
U.M. Nagamalesh, Ravi Shankar Shetty, Ravi Narayan, Anil Kumar, Ravi Naik, Sadath Uzma, K.C. Karthik Naidu   +6 more
doaj   +1 more source

Guided Tissue Regeneration in Heart Valve Replacement: From Preclinical Research to First-in-Human Trials [PDF]

, 2015
Heart valve tissue-guided regeneration aims to offer a functional and viable alternative to current prosthetic replacements. Not requiring previous cell seeding and conditioning in bioreactors, such exceptional tissue engineering approach is a very ...
Gerosa, Gino, Iop, Laura
core   +4 more sources

Ocular Findings as the Most Striking Manifestation of a SMAD3 Variant

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Loeys‐Dietz syndrome (LDS) is a heritable connective tissue disorder with variable expressivity. It is a multisystemic condition mainly characterized by a propensity for arterial aneurysms and dissections, skeletal manifestations, hypertelorism, bifid uvula, craniosynostosis, and cutaneous features.
Noémie Villeneuve‐Cloutier, Christie A Boswell‐Patterson, Lucas Bronicki, Krista M. Vincent, Kalin Wilk, Andrea C. Yu, Gail E. Graham, Julie Richer   +7 more
wiley   +1 more source

AP2M1 Is a Candidate Gene for Microcephaly and Intellectual Disability in 3q27.1 Deletions

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Deletions of the 3q26.33q27.2 region appear to correlate with a distinct phenotype, although there are few reported cases. Here, we present seven previously unreported individuals carrying de novo 3q27 deletions (under 5 Mb), which include the AP2M1 (adaptor‐related protein complex 2, mu‐1 subunit) gene and summarize data from 12 previously ...
Russell Gear, Paul Kalitsis, Melissa Glass, Bertrand Isidor, Catherine Vincent‐Delorme, Florence Petit, Judith M. A. Verhagen, Alexander Jorge, Ana Cristina Victorino Krepischi, Ikeoluwa Osei‐Owusu, Eva Martinez, Anne O'Donnell‐Luria, Nicole de Leeuw, Sarah Ruggiero, Ingo Helbig, Francis David I, Natasha J. Brown   +16 more
wiley   +1 more source

Iatrogenic non-coronary leaflet perforation as a complication after robotic mitral valve repair

Journal of Cardiothoracic Surgery
Iatrogenic aortic regurgitation secondary to leaflet injury is a rare complication of mitral valve surgery. For the first time, we report a patient who had progressive aortic regurgitation due to non-coronary leaflet perforation after robotic mitral ...
Afksendiyos Kalangos, Yilmaz Zorman, Emel Celiker Güler, Nataliia Shatelen   +3 more
doaj   +1 more source

Mixed Valvular Disease Following Transcatheter Aortic Valve Replacement: Quantification and Systematic Differentiation Using Clinical Measurements and Image-Based Patient‐Specific In Silico Modeling [PDF]

, 2020
Background: Mixed valvular disease (MVD), mitral regurgitation (MR) from pre‐existing disease in conjunction with paravalvular leak (PVL) following transcatheter aortic valve replacement (TAVR), is one of the most important stimuli for left ventricle (LV)
Amrute, Junedh M., Ben-Assa, Eyal, Blanke, Philipp, Brown, Jonathan, de la Torre Hernandez, Jose M., Edelman, Elazer R., Garcia Camarero, Tamara, Keshavarz-Motamed, Zahra, Khodaei, Seyedvahid, Lee, Suk Joon, Leipsic, Jonathon, Rikhtegar Nezami, Farhad, Ruano Calvo, Javier, Sellers, Stephanie   +13 more
core   +1 more source