Results 101 to 110 of about 296,180 (402)

Direct Access Valve Replacement (DAVR) — are we entering a new era in cardiac surgery? [PDF]

open access: yes, 2017
Objective: This study validates the off-pump antegrade trans-ventricular route for ultrasound-guided direct access aortic valve replacement. Direct access aortic valve replacement using a transthoracic and valved stent-based approach offers numerous ...
Huber, Christoph H.   +1 more
core  

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

open access: yesAdvanced Science, EarlyView.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong   +22 more
wiley   +1 more source

Surgery of the aortic root: should we go for the valve-sparing root reconstruction or the composite graft-valve replacement is still the first choice of treatment for these patients?

open access: yesBrazilian Journal of Cardiovascular Surgery, 2015
Objective:To compare the results of the root reconstruction with the aortic valve-sparing operation versus composite graftvalve replacement.Methods:From January 2002 to October 2013, 324 patients underwent aortic root reconstruction.
Fernando de Azevedo Lamana   +7 more
doaj   +1 more source

Procedural Volume and Outcomes for Transcatheter Aortic-Valve Replacement.

open access: yesNew England Journal of Medicine, 2019
BACKGROUND During the introduction of transcatheter aortic-valve replacement (TAVR) in the United States, requirements regarding procedural volume were mandated by the Centers for Medicare and Medicaid Services as a condition of reimbursement.
S. Vemulapalli   +13 more
semanticscholar   +1 more source

The use of transgenic animals for xenotransplantation: An update

open access: yesAnimal Models and Experimental Medicine, EarlyView.
One way to produce genetically modified pigs is to use somatic cell nuclear transfer (SCNT). This procedure involves removing the metaphase plate from a mature oocyte using micromanipulation and then transferring the modified nucleus from the donor somatic cell to the oocyte.
Julia Motławska   +3 more
wiley   +1 more source

Transcatheter Aortic Valve Replacement Programs: Clinical Outcomes and Developments

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
: Transcatheter aortic valve replacement is a relatively recent revolutionary treatment that has now become a standard procedure for treating severe aortic stenosis.
Vinayak Kumar   +4 more
doaj   +1 more source

Association Between Transcatheter Aortic Valve Replacement and Early Postprocedural Stroke.

open access: yesJournal of the American Medical Association (JAMA), 2019
Importance Reducing postprocedural stroke is important to improve the safety of transcatheter aortic valve replacement (TAVR). Objective This study evaluated the trends of stroke occurring within 30 days after the procedure during the first 5 years ...
Chetan P. Huded   +12 more
semanticscholar   +1 more source

Noradrenergic and cholinergic innervation of the normal human heart and changes associated with cardiomyopathy

open access: yesThe Anatomical Record, EarlyView.
Abstract Autonomic nerves are crucial in cardiac function and pathology. However, data on the distribution of cholinergic and noradrenergic nerves in normal and pathologic human hearts is lacking. Nonfailing donor hearts were pressure‐perfusion fixed, imaged, and dissected. Left ventricular cardiomyopathy samples were also obtained.
Peter Hanna   +16 more
wiley   +1 more source

Acute Mitral Valve Regurgitation Caused by Left Ventricular Pacing Wire During Transcatheter Aortic Valve Replacement [PDF]

open access: yesTexas Heart Institute Journal
Transcatheter aortic valve replacement is quickly becoming the standard of care for patients with severe aortic stenosis thanks to its minimally invasive nature and favorable outcomes.
Byeng-Ju Son, MD   +5 more
doaj   +1 more source

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