Results 171 to 180 of about 16,952 (210)

Progression of calcific aortic valve sclerosis in WHHLMI rabbits

Atherosclerosis, 2018
Aortic valve stenosis (AS) is the most common valvular heart disease and can be life-threatening. The pathogenesis of aortic valve calcification remains largely unknown, primarily due to the lack of an adequate animal model. The high-cholesterol diet-induced AS model in rabbits is one of the established models, but it has the significant limitation of ...
Tetsuya Hara, Norie Tsukada, Mitsumasa Okano, Tatsuro Ishida, Ken-ichi Hirata, Masashi Shiomi   +5 more
openaire   +2 more sources

Identification of tissue factor in experimental aortic valve sclerosis

Cardiovascular Pathology, 2009
Aortic valve sclerosis (AVS) shares epidemiological and histological similarities with atherosclerosis. Tissue factor (TF), the main initiator of blood coagulation, is present in atherosclerotic plaques and contributes to their thrombogenicity. We aimed to analyze valvular TF expression in addition to other components of atherosclerosis in two models ...
Sylvestre, Marechaux, Delphine, Corseaux, Andre, Vincentelli, Marjorie, Richardson, Alexandre, Ung, Sophie, Susen, Christophe, Zawadzki, Jean-Paul, Beregi, Michael D, Ezekowitz, Brigitte, Jude, Thierry, Le Tourneau   +10 more
openaire   +2 more sources

Correlation between epicardial fat thickness and aortic valve sclerosis

Asian Cardiovascular and Thoracic Annals, 2018
Background Epicardial fat is a true visceral fat deposit with adverse effects through the secretion of numerous proinflammatory and proatherogenic cytokines. Previous studies showed an association between aortic valve sclerosis and coronary artery disease.
Maryam Nabati, Maryam Favaedi, Masoud Kheirgoo, Jamshid Yazdani, Mozhdeh Dabirian   +4 more
openaire   +2 more sources

Aortic valve sclerosis, mitral annular calcium, and aortic root sclerosis as markers of atherosclerosis in men

The American Journal of Cardiology, 2002
Aortic valve sclerosis (AVS) and mitral annular calcium (MAC) as detected by transthoracic echocardiography have been associated with atherosclerosis. Aortic root sclerosis (ARS) may have a similar association, but has not been studied. This study evaluates, by transesophageal echocardiography, the association of AVS, MAC, and ARS with aortic ...
Kirsten, Tolstrup, Carlos A, Roldan, Clifford R, Qualls, Michael H, Crawford   +3 more
openaire   +2 more sources

Aortic valve sclerosis is associated with lower serum adiponectin levels

Journal of Cardiovascular Medicine, 2015
The sclerotic lesions of the aortic valve share common features with atherosclerosis. An anti-inflammatory protein, adiponectin, seems to have a protective effect on the cardiovascular system. The goal of our study is to determine adiponectin levels in patients with aortic sclerosis and to compare these values with the control group with similar age ...
Gizem, Çabuk, Umit, Guray, Habibe, Kafes, Yesim, Guray, Ali Kemal, Cabuk, Pinar T, Bayir, Lale D, Asarcikli   +6 more
openaire   +2 more sources

Evaluation of a porcine model of early aortic valve sclerosis

Cardiovascular Pathology, 2014
Calcific aortic valve disease (CAVD) is associated with significant cardiovascular morbidity. While late-stage CAVD is well-described, early pathobiological processes are poorly understood due to the lack of animal models that faithfully replicate early human disease.
Krista L. Sider, Cuilan Zhu, Andrea V. Kwong, Zahra Mirzaei, Cornelius F.M. de Langé, Craig A. Simmons   +5 more
openaire   +2 more sources

The association between CHA2DS2-VASc score and aortic valve sclerosis

Cardiovascular Journal of Africa
Antithrombotic therapy in atrial fibrillation is generally managed with the CHA2DS2-VASc score. Aortic valve sclerosis (AVS) is a focal thickening of the aortic valve without a restriction of motion. AVS is related to several cardiovascular risk factors.
Funda, Başyiğit, Havva Tuğba, Gürsoy, Özlem Özcan, Çelebi, Kevser Gülcihan, Balcı, Özgül Uçar, Elalmış, Kerem, Özbek, Özge Çakmak, Karaaslan, Mehmet, Ileri, Telat, Keleş, Sinan, Aydoğdu   +9 more
openaire   +2 more sources

Progression of aortic valve sclerosis and aortic valve stenosis: what is the role of statin treatment?

Italian heart journal : official journal of the Italian Federation of Cardiology, 2005
It has recently been suggested that statins could slow the progression of aortic stenosis, but this hypothesis has not been validated in large series. Moreover, there is little information about the role of statin treatment in patients with aortic valve sclerosis.From our database 1988--2002, we retrospectively identified 1136 consecutive patients with
Francesco, Antonini-Canterin, Bogdan A, Popescu, Guoqian, Huang, Renata, Korcova-Miertusova, Dante, Rivaben, Pompilio, Faggiano, Daniela, Pavan, Rita, Piazza, Angiola, Bolis, Antonio, Ciavattone, Alberto, Ruggiero, Gian Luigi, Nicolosi   +11 more
openaire   +1 more source

Inflammation, infection, and aortic valve sclerosis

Atherosclerosis, 2004
Yoram Agmon, Bijoy K Khandheria, A Jamil Tajik, James B Seward, JoRean D Sicks, Angela J Fought, W Michael O’Fallon, Thomas F Smith, David O Wiebers, Irene Meissner   +9 more
openaire   +1 more source

Aortic valve sclerosis is associated with an echocardiographically determined thinner aortic wall.

The Journal of heart valve disease, 2006
The aortic valve leaflets plus the aorta and sinuses of Valsalva are a functional unit that optimizes distribution of the diastolic pressure load on the aortic valve leaflets. The study aim was to examine the hypothesis that echocardiographically measured parameters of aortic wall stress at the level of the sinuses of Valsalva, namely aortic wall ...
Simon W, Rabkin, John, Jue, Michael Y, Tsang   +2 more
openaire   +1 more source