Results 101 to 110 of about 540,225 (295)

Disruption of Notch1 and Gata5 in Mice Leads to Congenital Aortic Valve Disease

JACC: Basic to Translational Science
Summary: Here, we describe Notch1;Gata5 compound mutant mice as a novel mouse model of highly penetrant congenital aortic valve disease displaying bicuspid aortic valve and progressive aortic valve stenosis.
Jun Yasuhara, MD, PhD, Mona Aljuhani, PhD, Talita Z. Choudhury, PhD, Anupama Rao, PhD, Sara Conroy, PhD, Yukie Ueyama, DVM, Stephanie LaHaye, PhD, Karlee Schultz, MS, Emily M. Cameron, MS, Sathiya N. Manivannan, PhD, Uddalak Majumdar, PhD, Vidu Garg, MD   +11 more
doaj   +1 more source

Comparative performance of risk prediction indices for mortality or readmission following heart failure hospitalization

ESC Heart Failure, Volume 12, Issue 2, Page 1227-1236, April 2025.
Comparative performance of 7 risk prediction indices in patients hospitalized for heart failure. In this cohort of 1206 patients, the LENT index offered the greatest discrimination, calibration, and overall accuracy in predicting 30‐day composite all‐cause mortality or readmission following hospitalization for heart failure.
Tauben Averbuch, Ali Zafari, Shofiqul Islam, Shun Fu Lee, Rajiv Sankaranarayanan, Stephen J Greene, Mamas A Mamas, Ambarish Pandey, Harriette GC Van Spall   +8 more
wiley   +1 more source

Transapical valve-in-valve implantation for regurgitant stented aortic bioprostheses

, 2012
Transcatheter aortic valve implantation (TAVI) is rapidly evolving as an alternative treatment option for elderly patients with severe symptomatic aortic stenosis and excessive risk for surgical intervention.
Windecker, Stephan, Carrel, Thierry, Pilgrim, Thomas, Wenaweser, Peter, Kadner, Alexander, Stortecky, Stefan   +5 more
core   +1 more source

Updates on transcatheter aortic valve replacement: Techniques, complications, outcome, and prognosis

Journal of the Saudi Heart Association, 2018
Transcatheter aortic valve replacement (TAVR) initially emerged as a therapeutic option for high-risk patients with severe aortic stenosis. Advancement in technologies since the first era of TAVRs, experience from previous obstacles, and lessons learned ...
Jarrah Alfadhli, Mohammed Jeraq, Vikas Singh, Claudia Martinez   +3 more
doaj   +1 more source

The Immediate And Intermediate Results Of Percutaneous Balloon Aortic Valvuloplasty In Patients With Congenital Valvular Aortic Stenosis

مجله كليه طب الكندي, 2019
Background: Aortic valve stenosis results from minor to severe degrees of aortic valve maldevelopment. This stenosis causes mild to severe obstruction of the left ventricular outflow .
Hussein A. Alwahab
doaj   +1 more source

Increased calcification by erythrophagocytosis in aortic valvular interstitial cells

ESC Heart Failure, Volume 12, Issue 2, Page 1469-1473, April 2025.
Abstract Background Calcific aortic valve disease (CAVD) progresses over time to severe aortic stenosis and eventually heart failure. Recent evidence indicates that intraleaflet haemorrhage (ILH) strongly promotes CAVD progression. However, it remains poorly understood how it mechanistically contributes to valvular calcification.
Zihan Qin, Magnus Bäck, Anders Franco‐Cereceda, Sven‐Christian Pawelzik   +3 more
wiley   +1 more source

Prognostic role of TAPSE to PASP ratio in outpatients with left ventricular systolic dysfunction

ESC Heart Failure, Volume 12, Issue 2, Page 912-922, April 2025.
Abstract Aims Few data are available regarding the role of tricuspid annulus plane systolic excursion to pulmonary artery systolic pressure (TAPSE/PASP), a measurement of right ventricular to pulmonary artery coupling, in patients with chronic heart failure and left ventricular systolic dysfunction.
Mauro Riccardi, Matteo Pagnesi, Rossana Corso, Antonio M. Sammartino, Daniela Tomasoni, Riccardo M. Inciardi, Carlo M. Lombardi, Marianna Adamo, Savina Nodari, Marco Metra   +9 more
wiley   +1 more source

Sixteen year retrospective analysis of rheumatic and non-rheumatic heart disease patients undergoing valve procedures at Groote Schuur Hospital first incidence single aortic and mitral valve replacement [PDF]

, 2012
Includes abstract.Includes bibliographical references.Rheumatic heart disease is still the most common cause of valvular heart lesions requiring replacement or repair procedures worldwide.
Ogunrombi, Akinwumi Babatunde
core   +1 more source

Impact of coronary artery disease and percutaneous coronary intervention on outcomes in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation

, 2011
Coronary artery disease (CAD) is frequently present in patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI).
Thierry Carrel, Windecker, Stephan, Buellesfeld, Lutz, Guerios, Enio, Thomas Pilgrim, Peter Wenaweser, Bernhard Meier, Wenaweser, Peter, Christoph Huber, Stortecky, Stefan, Huber, Christoph, Carrel, Thierry, Stephan Windecker, Steffen Gloekler, Lutz Buellesfeld, Pilgrim, Thomas, Ahmed A. Khattab, Kadner, Alexander, Enio Guerios, Khattab, Ahmed A, Gloekler, Steffen, Meier, Bernhard, Stefan Stortecky, Alexander Kadner, Buellesfeld L, Windecker S, Wenaweser P, Meier B, Khattab AA, Kadner A, Huber C, Guerios E, Pilgrim T, Carrel T, Gloekler S, Stortecky S   +35 more
core   +1 more source

A phenomap of TTR amyloidosis to aid diagnostic screening

ESC Heart Failure, Volume 12, Issue 2, Page 1113-1118, April 2025.
Abstract Cardiac amyloidosis due to transthyretin (ATTR) remains an underdiagnosed cause of cardiomyopathy. As awareness of the disease grows and referrals for ATTR increase, clinicians are likely to encounter more atypical forms of the condition in clinical practice.
Alexios S. Antonopoulos, Theodoros Tsampras, George Lazaros, Konstantinos Tsioufis, Charalambos Vlachopoulos   +4 more
wiley   +1 more source