Dynamic simulation of aortic valve stenosis using a lumped parameter cardiovascular system model with flow regime dependent valve pressure loss characteristics [PDF]
Valvular heart diseases are growing concern in impoverished parts of the world, such as Southern-Africa, claiming more than 31 % of total deaths related to cardiovascular diseases. The ability to model the effects of regurgitant and obstructive lesions on the valve body can assist clinicians in preparing personalised treatments.
arxiv
NRC-Net: Automated noise robust cardio net for detecting valvular cardiac diseases using optimum transformation method with heart sound signals [PDF]
Cardiovascular diseases (CVDs) can be effectively treated when detected early, reducing mortality rates significantly. Traditionally, phonocardiogram (PCG) signals have been utilized for detecting cardiovascular disease due to their cost-effectiveness and simplicity. Nevertheless, various environmental and physiological noises frequently affect the PCG
arxiv +1 more source
Sex discrepancies in pathophysiology, presentation, treatment, and outcomes of severe aortic stenosis [PDF]
This review gives an overview of sex-based differences in aortic valve stenosis, spanning from pathophysiological mechanisms and disease progression, clinical presentation, presence of comorbidities, and diagnostic assessment, to treatment and outcomes ...
Stehli, Julia+2 more
core +1 more source
Experimental aortic valve stenosis in rabbits
We studied a known rabbit model of atherosclerosis to assess the effect of a hypercholesterolemic diet on aortic valve morphology and function. We also evaluated the effects of the combination of this diet with vitamin D supplements on the development of the disease and the occurrence of valve calcification.Aortic valve stenosis (AVS) is the most ...
Marie Arsenault+2 more
openaire +3 more sources
In the Western world, calcified aortic valve stenosis is the most common form of valvular heart disease, affecting up to 3% of adults over the age of 75 years.
Luciana Thiago+4 more
doaj +1 more source
Subtype of atrial fibrillation and the outcome of transcatheter aortic valve replacement: The FinnValve Study [PDF]
Whether the subtype of atrial fibrillation affects outcomes after transcatheter aortic valve replacement for aortic stenosis is unclear. The nationwide FinnValve registry included 2130 patients who underwent primary after transcatheter aortic valve ...
Airaksinen, K. E. Juhani+16 more
core +1 more source
Wall shear stress and pressure patterns in aortic stenosis patients with and without aortic dilation captured by high-performance image-based computational fluid dynamics [PDF]
Spatial patterns of elevated wall shear stress and pressure due to blood flow past aortic stenosis (AS) are studied using GPU-accelerated patient-specific computational fluid dynamics. Three cases of moderate AS, one with a dilated ascending aorta and two within the normal range (root diameter less than 4cm) are simulated for physiological beat cycle ...
arxiv
TAVI in Africa - Destined for the townships or dashing for the “ivory towers”? [PDF]
Few treatments in the field of cardiology are more established than surgical aortic valve replacement for symptomatic severe aortic stenosis. It is estimated that over a million of these procedures have been performed since the first implant half a ...
Doubell, Anton
core +2 more sources
Uncover Hidden Physical Information of Soft Matter by Observing Large Deformation
Detecting internal abnormalities in soft matter remains challenging due to its heterogeneous nature. This study introduces a method that infers hidden physical properties by matching observed deformation with simulation through parallel Bayesian optimization.
Huanyu Yang+9 more
wiley +1 more source
RVD predicts outcome after M‐TEER for PMR. CI, confidence interval; HR, hazard ratio; PMR, primary mitral regurgitation; RVD, right ventricular dysfunction. Abstract Aims Right ventricular dysfunction (RVD), as expressed by right ventricular to pulmonary artery coupling, has recently been identified as a strong outcome predictor in patients undergoing ...
Philipp M. Doldi+39 more
wiley +1 more source