Results 191 to 200 of about 1,860,159 (292)

Targeted delivery of the CB2 receptor agonist JWH‐133 via VCAM‐1‐functionalised nanoparticles attenuates atherosclerosis and reveals sex‐specific therapeutic outcomes

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Atherosclerosis, a chronic inflammatory disease characterised by lipid accumulation and endothelial dysfunction, remains a leading cause of cardiovascular morbidity and mortality. While cannabinoid 2 (CB2) receptor agonists show therapeutic promise in preclinical studies, their systemic application is hindered by poor ...
Lucía Martín‐Navarro   +3 more
wiley   +1 more source

Trajectory of macrotroponin in a community cohort

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Cardiac troponin I (cTnI) is a biomarker for myocardial injury. However, macrotroponin, a complex of cTnI and endogenous cardiac troponin autoantibodies, may artefactually elevate cTnI levels with potential to mislead clinicians, leading to inappropriate investigation and management.
Duncan J. Campbell   +5 more
wiley   +1 more source

Refining Residual Ischemic Stroke Risk in Anticoagulated Atrial Fibrillation Using Index Outpatient LA Diameter: The CHA2DS2‐VALa Score

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
In anticoagulated atrial fibrillation, residual ischemic stroke risk persists despite guideline‐directed therapy. In this single‐center cohort, an enlarged index outpatient left atrial diameter independently predicted stroke and improved risk stratification when added to CHA2DS2‐VA (CHA2DS2‐VALa), supporting a simple, clinically implementable ...
Sefa Erdi Ömür   +7 more
wiley   +1 more source

Cardiac structure and function in psoriasis: A cross‐sectional analysis of the PSOCADIA study

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Individuals with well‐treated psoriasis exhibited a higher burden of myocardial dysfunction (GLS < 16%) compared with controls, independent of cardiometabolic comorbidity. The prevalence was similar across psoriasis severity, highlighting the importance of cardiovascular assessment in all patients with psoriasis. Abstract Background Psoriasis is linked
Maria Dons   +16 more
wiley   +1 more source

Outcomes of reoperative aortic valve surgery: data from a national registry over 23 years. [PDF]

open access: yesIndian J Thorac Cardiovasc Surg
Narayan P   +7 more
europepmc   +1 more source

Unmasking of pre-excitation after aortic valve surgery - A report of two cases. [PDF]

open access: yesHeartRhythm Case Rep, 2021
Tapanainen JM   +5 more
europepmc   +1 more source

Frailty and Five‐Year Mortality After TAVR in Patients Aged 75 Years and Older

open access: yesJournal of the American Geriatrics Society, EarlyView.
In patients aged 75 years and older undergoing transcatheter aortic valve replacement, frailty assessed by the Clinical Frailty Scale was the most robust geriatric factor independently associated with five‐year mortality. This study highlights the specific prognostic value of frailty beyond short‐term outcomes.
Jérémie Huet   +4 more
wiley   +1 more source

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