Results 51 to 60 of about 1,860,159 (292)

Two stage surgical repair of type II acute aortic dissection and aortic coarctation in a 12-year-old child [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2017
Introduction. Combination of acute aortic dissection associated with aortic coarctation in pediatric population is extremely rare. We are presenting a 12-year-old patient with these two conditions who was successfully treated with two-stage surgery. Case
Milovanović Vladimir, Vulićević Irena, Zečević Tatjana, Đukić Milan, Ilić Slobodan, Mimić Branko   +5 more
doaj   +1 more source

Reconstructive surgery for aortic valve disease [PDF]

Arquivos Brasileiros de Cardiologia, 2000
CECORP-Centro Especializado do Coracao e Pulmao de Ribeirao Preto, Hospitaldo Coracao de Ribeirao Preto/Fundacao Waldemar B. Pessoa, Faculdade deMedicina de Ribeirao Preto-USP e Faculdade de Medicina da UNAERPMailing adress: Paulo J. F.
Paulo José F. Ribeiro, Paulo Roberto B. Évora, Walter V. A. Vicente, Antonio Carlos Menardi   +3 more
openaire   +3 more sources

The Deubiquitinase UCHL1 Drives Susceptibility to Atrial Fibrillation by Stabilizing CaMKII‐δ

Advanced Science, EarlyView.
UCHL1 is highly upregulated in mice and patients with AF. UCHL1 directly binds to and removes K48‐linked polyubiquitin chains from CaMKII‐δ at K251 and enhances CaMKII‐δ stability, which activates RyR2, disrupts Ca2+ handling, and promotes AF. These findings establish UCHL1 as a critical regulator of CaMKII‐δ stability and AF‐related Ca2+ handling ...
Hai‐Lian Bi, Yu‐Hui Gu, Kai‐Wen Ren, Xiao‐Hong Yu, Yun‐Long Xia, Xiao‐Lei Yang, Hui‐Hua Li   +6 more
wiley   +1 more source

Sixteen year retrospective analysis of rheumatic and non-rheumatic heart disease patients undergoing valve procedures at Groote Schuur Hospital first incidence single aortic and mitral valve replacement [PDF]

, 2012
Includes abstract.Includes bibliographical references.Rheumatic heart disease is still the most common cause of valvular heart lesions requiring replacement or repair procedures worldwide.
Ogunrombi, Akinwumi Babatunde
core   +1 more source

Bicuspid aortic valve: different clinical profiles for subjects with versus without repaired aortic coarctation

Open Heart, 2020
Objectives A small proportion of patients undergoing bicuspid aortic valve (BAV) intervention have had prior repair of aortic coarctation (CoA). We aimed to describe phenotypic differences between BAV patients, comparing those with versus those without ...
Paul G Bannon, Michelle S Lim
doaj   +1 more source

Surgical treatment for accidentally discovered pseudoaneurysm of the mitral-aortic intervalvular fibrosa with bicuspid aortic valve, ascending aortic aneurysm, and myocardial ischemia: a case report

The Cardiothoracic Surgeon, 2021
Background Pseudoaneurysm of the mitral-aortic intervalvular fibrosa (P-MAIVF) is a rare complication of infective endocarditis and aortic valve replacement. Ruptured P-MAIVF and angina due to compression of the coronary arteries are severe complications
Kentaro Kiryu, Gembu Yamaura, Itaru Igarashi, Takayuki Kadohama, Fuminobu Tanaka, Daichi Takagi, Yoshinori Itagaki, Takeshi Arai, Takuya Wada, Hiroshi Yamamoto   +9 more
doaj   +1 more source

Vine‐Inspired Soft Robotics: Materials, Actuations, and Emerging Applications

Advanced Science, EarlyView.
Vine‐inspired robots grow from the tip, enabling navigation through confined spaces with minimal disturbance. This Review summarizes material and actuation strategies for vine‐inspired growth, key functions including steering, retraction, attachment, branching, and variable stiffness, and emerging applications spanning medical intervention, confined ...
Jiahao Wu, Xingyun Liu, Fangzhou Wang, Huili Ren, Chaojun Zhang, Ziyu Ren, Zunqi Liu, Jing Li   +7 more
wiley   +1 more source

Heterozygous Variants in LRP1 Cause a Neurodevelopmental Disorder With Congenital Heart Defects

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT LRP1 encodes the low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1), a transmembrane protein involved in endocytosis and activation of multiple signaling pathways. LRP1 variants have been implicated in the pathogenesis of congenital heart defects (CHD), Alzheimer's disease, and neurodevelopmental disorders (NDD).
Alyssa L. Rippert, Gudny Anna Arnadottir, Laura Bedinger, Nicola Brunetti‐Pierri, Jennifer Cech, Xin Chen, Yanmin Chen, Erika Chick, Sarah Dyack, Madeleine Franchi, Tanja Frey, David Genevieve, Ian Glass, Jorge Granadillo, Kelly A. Keener, Sara B. MacKay, Paige McDunnah, Vinod K. Misra, Kristin G. Monaghan, Sureni V. Mullegama, Cristina Peduto, Leia Peterman‐Prather, Anita Rauch, Cherith Somerville, Kari Stefansson, Katharina Steindl, Patrick Sulem, Telma Sulem, Pamela Trapane, Roberta Zeuli, Samuel Zinner, Kosuke Izumi   +31 more
wiley   +1 more source

Systematic Cardiac Phenotyping of Patients With Copy Number Variants in the 15q11.2 Breakpoint 1 to Breakpoint 2 Region: A Retrospective Cohort Study From Nine Pediatric Cardiac Centers

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Microdeletions impacting 15q11.2 breakpoint (BP) 1 to BP2, adjacent to the Prader–Willi critical region, have previously described neuropsychiatric associations, with potential low penetrance presentations of congenital heart disease (CHD) also identified.
Morgan B. Wright, Maria B. Padua, Lindsey R. Helvaty, Kim L. McBride, Gabrielle Geddes, Vidu Garg, Seema R. Lalani, Stephanie Burns Wechsler, Jennelle C. Hodge, Benjamin J. Landis, Stephanie M. Ware   +10 more
wiley   +1 more source

Longitudinal Echocardiographic Surveillance of Aortic Dilation in a Phenotype‐Enriched Turner Syndrome Cohort

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Turner syndrome (TS) is associated with thoracic aortopathy and increased risk for aortic dissection, yet the natural history of aortic dilation is not well understood. We performed a retrospective longitudinal study of individuals with TS who participated in the TS Society of the United States Healthy Heart Project between 2003 and 2023 ...
Dylan Doerner, Matthew R. Johnson, Sara Mansoorshahi, Rakesh Kathiresan, Katelyn Abel, Jonathan G. You, Emilio Quezada, Siddharth K. Prakash   +7 more
wiley   +1 more source