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Heart, 2022
Aortic dissection is one of the most common causes of death in pregnancy. Most cases are caused by hereditary thoracic aortopathy (HTA), and women are often unaware they are at risk. Awareness, early recognition and involvement of senior clinicians from the expert cardio-obstetric team are essential to facilitate early diagnosis and carefully planned ...
Stephanie Louise Curtis, Lorna Swan
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Aortic dissection is one of the most common causes of death in pregnancy. Most cases are caused by hereditary thoracic aortopathy (HTA), and women are often unaware they are at risk. Awareness, early recognition and involvement of senior clinicians from the expert cardio-obstetric team are essential to facilitate early diagnosis and carefully planned ...
Stephanie Louise Curtis, Lorna Swan
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Imaging of Genetic Thoracic Aortopathy
RadioGraphics, 2022Aortopathy is a term most commonly used to describe a group of genetic diseases that predispose patients to an elevated risk of aortic events including aneurysm and acute aortic syndrome. Types of genetic aortopathy are classified as either heritable or congenital, with heritable thoracic aortic disease (HTAD) further subclassified into syndromic HTAD ...
Kacie L. Steinbrecher +7 more
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Progress in Cardiovascular Diseases, 2020
The aortopathy associated with bicuspid aortic valve (BAV) is an epidemiologically relevant source of chronic and acute aortic disease (aneurysm and dissection). However, its pathogenesis is still the object of scientific uncertainties and debates. Indeed, the mechanisms determining the diseases of the ascending aorta in BAV patients are most likely ...
Lo Presti, Federica +4 more
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The aortopathy associated with bicuspid aortic valve (BAV) is an epidemiologically relevant source of chronic and acute aortic disease (aneurysm and dissection). However, its pathogenesis is still the object of scientific uncertainties and debates. Indeed, the mechanisms determining the diseases of the ascending aorta in BAV patients are most likely ...
Lo Presti, Federica +4 more
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Genetic Biomarkers in Aortopathy
Biomarkers in Medicine, 2013The field of aortopathy, in common with other genomic disorders, is undergoing a revolution. This is largely driven by the implementation of newer forms of genetic sequencing (massively parallel or next-generation sequencing). Advantages conferred by this technology include reduced costs, reduced sequencing time and the ability to simultaneously test ...
Gillian, Rea, Fiona J, Stewart
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Inherited aortopathy: an overview
British Journal of Cardiac Nursing, 2023This article is the fourth instalment of a wider series looking at cardiac genetic concepts. Inherited aortopathies are a group of syndromic and non-syndromic genetic conditions that affect the aorta. Aortopathies can lead to sudden cardiac death through aortic aneurysm rupture, especially in individuals whose aortopathy is undiagnosed.
Fortunate Mamombe +7 more
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Aortopathy in Congenital Heart Disease
Cardiology Clinics, 2020Aortic dilatation is common in patients with congenital heart disease and is seen in patients with bicuspid aortic valve and those with conotruncal congenital heart defects. It is important to identify patients with bicuspid aortic valve at high risk for aortic dissection.
Timothy B, Cotts +3 more
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Seminars in Perinatology, 2014
Up to half of all aortic dissections and ruptures in women younger than 40 years are associated with pregnancy. In pregnancy, women with aortic disease such as arteritis and aortitis are at significant risk of aneurysmal formation and dissection with potential for catastrophic outcomes.
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Up to half of all aortic dissections and ruptures in women younger than 40 years are associated with pregnancy. In pregnancy, women with aortic disease such as arteritis and aortitis are at significant risk of aneurysmal formation and dissection with potential for catastrophic outcomes.
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Idiopathic medial aortopathy and arteriopathy
The American Journal of Medicine, 1968Abstract Five patients showing similar lesions in the aorta and its great branches are described. All showed patchy destruction of the elastic and muscle fibers of the media, with secondary fibrosis of the intima and sometimes of the adventitia. None had clinical or serologic evidence of syphilis.
Y, Marquis +3 more
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Bicuspid aortic valve related aortopathy
General Thoracic and Cardiovascular Surgery, 2017Bicuspid aortic valve related aortopathy is known to significantly increase the risk for catastrophic aortic events and, therefore, represents a considerable health burden. Albeit of ongoing research in this field including genetic, molecular, hemodynamic and morphologic aspects, bicuspid aortic valve related aortopathy still represents an imperfectly ...
Sina, Stock +2 more
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