Results 131 to 140 of about 2,749 (160)

Aortopathy: Effects of Lipid-Lowering Therapy

Cardiology in Review, 2023
Aortopathies can be congenital or acquired. Aortic atherosclerosis, abdominal aortic aneurysm, and degenerative aortic stenosis are some of the major manifestations of acquired aortopathy. Dyslipidemia, an imbalance of plasma lipid levels, is strongly associated with common aortopathies.
Matthew, Vollaro, Tanya, Sharma, Mala, Sharma, William H, Frishman, Wilbert S, Aronow   +4 more
openaire   +2 more sources

Stenting in Aortopathies

2017
Transcatheter stent deployment within the aorta is generally used for two purposes: (1) relief of aortic obstruction as seen in aortic coarctation and (2) the use of covered stents to exclude an aneurysm or pseudoaneurysm of the aorta. For the purpose of relieving obstruction, balloon angioplasty alone is associated with reasonable short-term ...
Joanna Ghobrial, Jamil Aboulhosn
openaire   +1 more source

Update on bicuspid aortic valve aortopathy

Current Opinion in Cardiology, 2017
The appropriate treatment of bicuspid aortic valve (BAV)-associated aortopathy is still controversial. We aimed to summarize recent evidence from the literature that focused on the prediction of aortopathy progression and adverse aortic events.Following the detailed description of valvulo-aortic phenotypes in BAV disease in the previous imaging studies,
Girdauskas, Evaldas, Petersen, Johannes
openaire   +3 more sources

Genetic testing for aortopathies

Current Opinion in Cardiology, 2019
Although the majority of thoracic aortic aneurysms and dissections (TAD) in the overall population are mainly related to arterial hypertension and atherosclerosis, Heritable Thoracic Aortic Disease (HTAD) are increasingly recognized, especially in younger individuals.
De Backer, Julie, Jondeau, Guillaume, Boileau, Cathérine   +2 more
openaire   +3 more sources

Aortopathy in Marfan syndrome: an update

Cardiovascular Pathology, 2014
Marfan syndrome (MFS) is an inherited autosomal dominant multisystem disease caused by mutations in the FBN1 gene encoding fibrillin-1, an extracellular matrix glycoprotein widely distributed in mesenchymal-derived tissues that provide a scaffold for elastin deposition.
Romaniello, F, Mazzaglia, D, PELLEGRINO, ANTONIO, GREGO, SUSANNA, FIORITO, ROBERTO, FERLOSIO, AMEDEO, CHIARIELLO, LUIGI, ORLANDI, AUGUSTO   +7 more
openaire   +3 more sources

Genetics of syndromic and nonsyndromic aortopathies

Current Opinion in Pediatrics, 2019
Purpose of reviewTo review the literature and provide a summary of management of syndromic and nonsyndromic aortopathies.Recent findingsThe number of newly identified genetic causes for aortopathies have continued to increase over the past 10 years. The number of reported individuals with most hereditary aneurysm genes is small but increasing with more
Christina M, Rigelsky, Rocio T, Moran
openaire   +2 more sources

Aortopathies: Clinical Manifestation

2017
Many native, surgically or interventionally treated patients with congenital heart anomalies and genetic aortic syndromes (GAS) (e.g., Marfan, Loeys-Dietz, Ehlers-Danlos, Turner syndrome) are at risk for the development of aortic aneurysm, dissection, or rupture, resulting from inborn anomalies of the structure and metabolism of the aortic wall.
Harald Kaemmerer, Yskert von Kodolitsch
openaire   +1 more source

Non-coding RNAs in aneurysmal aortopathy

Vascular Pharmacology, 2019
Aortic aneurysms represent a major public health burden, and currently have no medical treatment options. The pathophysiology behind these aneurysms is complex and variable, depending on location and underlying cause, and generally involves progressive dysfunction of all elements of the aortic wall.
Joshua M, Spin, Daniel Y, Li, Lars, Maegdefessel, Philip S, Tsao   +3 more
openaire   +2 more sources

Echogenomics: Echocardiography in Heritable Aortopathies

Current Cardiology Reports
The aim of this article is to review the current echocardiographic considerations in the diagnosis and monitoring of patients with inherited aortopathies.Aortic dilation is a key feature in heritable aortopathies, and dissection is a leading cause of morbidity and mortality.
Lyndsey, Hunter-Adamson, Seda, Tierney
openaire   +2 more sources

Genetics of bicuspid aortic valve aortopathy

Current Opinion in Cardiology, 2016
The incidence of aortic dilation and acute complications (rupture and dissection) is higher in patients with a bicuspid aortic valve (BAV), the most frequent congenital heart defect.The present review focuses on the current knowledge in the genetics of BAV, emphasizing the clinical implications for early detection and personalized care.BAV is a highly ...
Andreassi, Maria G, DELLA CORTE, Alessandro   +1 more
openaire   +3 more sources