Results 221 to 230 of about 873,650 (292)

Akkermansia muciniphila drives viscero-visceral crosstalk via 5-HT_3aR-mediated sensitization of dichotomizing gut-bladder neurons. [PDF]

Exp Mol Med
Sun Q, Gao Y, Zheng J, Liao R, Jiang H, Zhu Z, Xie M, Yu Y, Zhu Y, Li W, Shangguan W, Li L, Shi X, Yang Q, Zeng J, Wang Z, Zhao J, Cheng B, Wu P.   +18 more
europepmc   +1 more source

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency

Advanced Science, EarlyView.
Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Qing Yang, Huimin Jiang, Chenyang Xiong, Xindi Zhou, Qinqin Tan, Han Xiao, Lan Qiu, Chun Gan, Yaxi Chen, Haiping Yang, Wei Jiang, Qiu Li   +11 more
wiley   +1 more source

Public Perception of Health Care Before, During, and After COVID-19: Longitudinal Analysis of Online Reviews. [PDF]

J Med Internet Res
Gazquez-Garcia J, Sánchez-Bocanegra CL, Fernandez-Llatas C.   +2 more
europepmc   +1 more source

Universal Battery Capacity Degradation Forecasting Driven by Foundation Models Across Diverse Chemistries and Conditions

Advanced Science, EarlyView.
A unified time‐series forecasting framework learns transferable battery capacity‐degradation patterns from 20 heterogeneous datasets spanning chemistries, formats, temperatures, and cycling conditions. A single model delivers competitive predictions on both known and previously unseen datasets, while physics‐guided representation learning improves ...
Joey Chan, Huan Wang, Zhen Chen, Haoyu Pan, Wei Wu, Zirong Wang, Ershun Pan, Min Xie, Lifeng Xi   +8 more
wiley   +1 more source

Estrogen Receptor Beta Isoforms Interplay Integrates Nuclear and Extra-Nuclear Signaling to Modulate Human Granulosa Cell Growth. [PDF]

FASEB J
Marie C, Baskaran IN, Corre R, Mayeur A, Grynberg M, Chevreux G, L'Hôte D, Cohen-Tannoudji J, Chauvin S.   +8 more
europepmc   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Nucleation of α-pinene oxidation products with sulfuric acid.

Environ Sci Atmos
Sommer E, Almeida J, Yu W, Simon M, Möller F, Xenofontos C, Pozzer A, Zheng Z, Bhattacharyya N, Alfaouri D, Atabakhsh S, Baalbaki R, Beckmann H, Berntheusel M, Bogert P, Busato M, Canagaratna M, Caudillo-Plath L, Chassaing A, Cruz-Simbron R, Dada L, DeVivo J, Duplissy J, Gordon H, Granzin M, Schute LG, Hartl HG, Hirvensalo E, Jacobshagen A, Judmaier B, Sebastian MK, Klebach H, Koemets P, Kohl M, Konrat R, Krüger T, Kunkler F, Kürten A, Leiminger M, Lietzke CJ, Liu L, Mauldin R, Mentler B, Morawiec A, Müller M, Petäjä T, Pignatelli A, Rato P, Reinecke T, Richter S, Rörup B, Ruhl S, Russell DM, Scholz W, Shen J, Stinchfield A, Thakur RC, Tong Y, Top J, Umo NS, Weissbacher J, Yang B, Zauner-Wieczorek M, Zhang J, Amorim A, Baltensberger U, Christoudias T, Curtius J, Donahue NM, El Haddad I, Flagan RC, Hansel A, Harder H, He XC, Junninen H, Kulmala M, Lehtipalo K, Lelieveld J, Möhler O, Schobesberger S, Tomé A, Volkamer R, Worsnop DR, Onnela A, Winkler PM, Kirkby J.   +85 more
europepmc   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

A Rare Case of Uncorrected Tetralogy of Fallot With Right Hemitruncus in an Adult Survivor Highlighting the Role of Cardiac Computed Tomography. [PDF]

Cureus
Choudhary J, Patel AV, Ratnaparkhi C, Dhok A, Anand KR.   +4 more
europepmc   +1 more source

Variations of the Ap Stars in NGC2169

, 1994
Manfroid, Jean, Renson, Pierre
openaire   +1 more source