Results 101 to 110 of about 7,987 (192)

Apatinib Promotes Ferroptosis in Colorectal Cancer Cells by Targeting ELOVL6/ACSL4 Signaling

Cancer Management and Research, 2021
Xiangyang Tian,1 Shuyuan Li,2 Guoyan Ge2 1Department of Oncology, Peace Hospital, Changzhi Medical College, Changzhi, Shanxi Province, 046000, People’s Republic of China; 2Department of Tumor Spleen and Stomach, Hospital of Traditional Chinese ...
Tian X, Li S, Ge G
doaj  

Comparison of drug-eluting bead transarterial chemoembolization combined with apatinib versus drug-eluting bead transarterial chemoembolization for the treatment of unresectable hepatocellular carcinoma: a randomized, prospective, multicenter phase III trial

Signal Transduction and Targeted Therapy
This randomized, prospective, multicenter (12 centers in China) phase III trial (Chinese Clinical Trial Registry #ChiCTR2000041170) compared drug-eluting bead transarterial chemoembolization (DEB-TACE) combined with apatinib and DEB-TACE monotherapy for ...
Xuhua Duan, Hao Li, Donglin Kuang, Pengfei Chen, Mengfan Zhang, Tengfei Li, Dechao Jiao, Yanliang Li, Xiang He, Cheng Xing, Haibo Wang, Yaoxian Liu, Limin Xie, Shixi Zhang, Qiang Zhang, Peixin Zhu, Yongchuang Chang, Jichen Xie, Jianzhuang Ren, Xinwei Han   +19 more
doaj   +1 more source

Safety and efficacy of apatinib in combination treatment versus apatinib as second-line treatment for advanced gastric cancer

Frontiers in Oncology
BackgroundApatinib is a systemic therapeutic agent for advanced gastric adenocarcinoma (GAC) and gastroesophageal junction adenocarcinoma (GEJA). Its efficacy can be enhanced by applying it as a combination therapy, but the evidence supporting its combination application as a second-line treatment is not well documented.
Zhang Han, Zhu Yuanzeng, Wu Gang, Sun Peichun   +3 more
openaire   +3 more sources

U251-Apatinib -Proteomics

Proteomics profiling reveals the potential targets of Apatinib inhibiting the proliferation of glioma U251 cellTHIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE.
Kong, D (via Mendeley Data)
core   +1 more source

Apatinib treatment for KIT- and KDR-amplified angiosarcoma: a case report

, 2018
Background Metastatic or relapsed angiosarcoma has a poor prognosis and the efficacy of conventional chemotherapy is often limited. Apatinib, a novel tyrosine kinase inhibitor (TKI) targeting vascular endothelial growth factor receptor-2 (VEGFR2), has ...
Meng Zhao, Bo Han, Lishu Yang, Wei Han, Lizhu Liu   +4 more
core   +1 more source

Apatinib in HSA-PEG inhibits VEGF-induced retinal vascular permeability and angiogenesis

, 2015
학위논문(석사)--아주대학교 일반대학원 :약학,2015. 8TABLE OF CONTENTS ABSTRACT i LIST OF FIGURES vii ABBREVIATION viii 1. INTRODUCTION 1 2. MATERIALS AND METHODS 4 2.1. Reagents 4 2.2. Cell culture 4 2.3. Cell viability assay 4 2.4.
KHANH, NGUYEN HON
core  

Apatinib enhances antitumour activity of EGFR-TKIs in non-small cell lung cancer with EGFR-TKI resistance

, 2017
Background: Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs)-rechallenged therapy for EGFR-mutant non-small cell lung cancer (NSCLC) patients who acquired resistance showed moderate efficacy.
Liang, Li, Li, Fang, Cao, Baoshan, Tengjiao Zhu, Jiadong Wang, Li Liang, Zhu, Tengjiao, Baoshan Cao, Fang Li, Wang, Jiadong   +9 more
core   +1 more source

Establishment and validation of a population pharmacokinetic model for apatinib in patients with tumors

Objective This study aimed to develop a population pharmacokinetic (PPK) model for oral apatinib in Chinese oncology patients and investigate the factors influencing the pharmacokinetics of apatinib. Methods We gathered 199 blood concentration monitoring
Nan Hu, Jing Ling, Li’an Zuo, Rong Chen   +3 more
core   +1 more source

Melatonin and Apatinib: Potential Therapeutic Agents in Cancer Treatment through Vascular Mimicry Formation: A Review [PDF]

Cancer is one of the most challenging diseases, affecting millions of individuals worldwide. This disease is caused by the abnormal and uncontrolled growth of cells, which leads to damage to various tissues and organs of the body.
Nazila Fathi Maroufi, Mohsen Rashidi
core  

TACE combined with apatinib versus TACE alone for unresectable hepatocellular carcinoma in China: a cost-effectiveness and budget impact analysis. [PDF]

BMJ Open
Zhang Y, Wang X, Huang Z, Huang L, Sun G.   +4 more
europepmc   +1 more source