Results 161 to 170 of about 7,987 (192)
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Apatinib-induced hyperammonemic encephalopathy
Journal of Oncology Pharmacy Practice, 2019Apatinib is an orally administered small-molecule vascular endothelial growth factor receptor-2 inhibitor that has demonstrated encouraging anticancer activity across a broad range of malignancies, including gastric cancer, non-small-cell lung cancer, breast cancer, and hepatocellular carcinoma.
Yan Liu +4 more
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Renal Ewing sarcoma treated with apatinib
Anti-Cancer Drugs, 2018Renal Ewing sarcoma (RES) is an extremely rare disease. The standard treatment for this disease is lacking, and clinical experience needs to be accumulated. Here, we report a case of RES that rapidly developed to metastatic disease and was refractory to radiotherapy and chemotherapy; however, the case obtained a partial response based on Choi criteria ...
Yang, Zhao +5 more
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Pharmacokinetic Drug Interactions of Apatinib With Rifampin and Itraconazole
The Journal of Clinical Pharmacology, 2017AbstractApatinib is a small‐molecule tyrosine kinase inhibitor that has been approved for the treatment of patients with advanced‐stage gastric cancer or gastroesophageal junction cancer who have progressed or recurred after at least 2 kinds of systemic chemotherapy.
Xiaoyun, Liu +9 more
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Apatinib beim therapierefraktären mGC
Im Focus Onkologie, 2013Patienten mit fortgeschrittenem chemotherapierefraktarem Magenkarzinom konnen bisher nur noch mit supportiver Behandlung unterstutzt werden. Jetzt wurde der neue VEGF-Rezeptor-Inhibitor Apatinib in einer Phase-II-Studie gepruft.
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Effect of apatinib on albendazole metabolism in vitro and in vivo
Bioorganic ChemistryAlbendazole is a broad-spectrum antiparasitic benzimidazole and has potential for the treatment of tumors. The aim of this study was to investigate the potential inhibitory effects of 77 drugs on the metabolism of albendazole, and further to elaborate the inhibitory mechanism of apatinib on albendazole metabolism in vitro and in vivo, where the ...
Hailun, Xia +7 more
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