Results 101 to 110 of about 187,448 (328)

Dual‐Targeting Cuproptosis and Mitophagy via a Flavopiridol‐Copper Nanoplatform Potentiates Immunotherapy Against Uveal Melanoma

Advanced Science, EarlyView.
This study develops a GSH‐responsive nanoplatform, NP@Fla‐Cu, to co‐activate cuproptosis and excessive mitophagy in uveal melanoma. The nanoplatform enhances tumor‐specific copper delivery, depletes antioxidant defenses, and remodels the tumor immune microenvironment.
Hong Ren, Zhihong Deng, Sheng Lu, Jing Zhang, Wenbin Liu, Jia Tan   +5 more
wiley   +1 more source

Automatic Selection of Machine Learning Models for Armed People Identification

IEEE Access
This research aims to improve the automatic identification of armed people in surveillance videos. We focus on people armed with pistols and revolvers. Furthermore, we use the YOLOv4 to detect people and weapons in each video frame. We developed a series
Alonso Javier Amado-Garfias, Santiago Enrique Conant-Pablos, Jose Carlos Ortiz-Bayliss, Hugo Terashima-Marin   +3 more
doaj   +1 more source

Optical communication with semiconductor laser diodes [PDF]

A 25 megabit/sec direct detection optical communication system that used Q=4 PPM signalling was constructed and its performance measured under laboratory conditions.
Davidson, F.
core   +2 more sources

FACT -- Operation of the First G-APD Cherenkov Telescope

, 2014
Since more than two years, the First G-APD Cherenkov Telescope (FACT) is operating successfully at the Canary Island of La Palma. Apart from its purpose to serve as a monitoring facility for the brightest TeV blazars, it was built as a major step to ...
Biland, A., Bretz, Thomas, Buss, J., Commichau, V., Djambazov, L., Dorner, D., Einecke, S., Eisenacher, D., FACT Collaboration, Freiwald, J., Grimm, O., Haller, C., Hempfling, C., Hildebrand, D., Horisberger, U., Hughes, G., Knoetig, M.-L., Krähenbühl, T., Lustermann, W., Lyard, E., Mannheim, K., Meier, K., Mueller, S., Neise, D., Overkemping, A.-K., Paravac, A., Pauss, F., Rhode, W., Röser, U., Steinbring, T., Stucki, J.-P., Temme, F., Thaele, J., Vogler, P., von Gunten, H., Walter, R., Weitzel, Q.   +36 more
core   +1 more source

Chemically Engineered L. reuteri Delivering αPD‐L1 and Gallium Ions via Metal‐Phenolic Networks Potentiate Anti‐Tumor Immunity and Ferroptosis

Advanced Science, EarlyView.
A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang, Mengyi Xu, Yan Zhang, Zhiwen Li, Danqing Song, Jing Pang, Ke Li, Yanxiang Wang   +7 more
wiley   +1 more source

Avalanche Photo-Detection for High Data Rate Applications

, 2007
Avalanche photo detection is commonly used in applications which require single photon sensitivity. We examine the limits of using avalanche photo diodes (APD) for characterising photon statistics at high data rates.
, C Silberhorn, Castelletto S Degiovanni I P Schettini V, H B Coldenstrodt-Ronge, Klyshko D N, Klyshko D N, Lorenz S Rigas J Heid M Andersen U L Lütkenhaus N Leuchs G, Mandel L, Penin A N, Rarity J G, Raymer M G, Rosenberg D, Silberhorn C Achilles D U'Ren A B Banaszek K Walmsley I A, Thew R T, Zavatta A   +14 more
core   +1 more source

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

Advanced Science, EarlyView.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang, Tianyu Shao, Fengjiang Qu, Caiyun Bai, Sijie Li, Pin Gao, Wenna Li, Keman Cheng, Xiao Zhao, Zhimin Fan   +9 more
wiley   +1 more source

Developmental and School-Related Risk Factors in Auditory Processing Disorder: A Pilot Study in Polish Children

Applied Sciences
The paper presents the issue of acquired and secondary auditory processing disorder (APD) in children and adolescents in the Polish population. The authors analyzed a group of individuals with APD and younger children who were at risk based on a detailed
Natalia Moćko, Arkadiusz Badziński, Michał Kręcichwost   +2 more
doaj   +1 more source

Repolarization Alternans and Ventricular Arrhythmia in a Repaired Tetralogy of Fallot Animal Model

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2015
Background Ventricular arrhythmia is an important cause of late death in patients with repaired tetralogy of Fallot (rTOF). By using an rTOF canine model, we investigated the role of repolarization alternans and its electrophysiological mechanisms ...
Shuenn‐Nan Chiu, Chia‐Ti Tsai, Lian‐Yu Lin, Shu‐Chien Huang, Yih‐Sharng Chen, Jou‐Kou Wang, Mei‐Hwan Wu, Ling‐Ping Lai, Jiunn‐Lee Lin   +8 more
doaj   +1 more source

An Approach to Automatic Indexing of Scientific Publications in High Energy Physics for Database SPIRES HEP

, 2002
We introduce an approach to automatic indexing of e-prints based on a pattern-matching technique making extensive use of an Associative Patterns Dictionary (APD), developed by us.
Averin, A. V., Vassilevskaya, L. A.
core   +2 more sources