Results 141 to 150 of about 158,301 (286)

Voice and Speech in Atypical Parkinsonian Disorders

Movement Disorders Clinical Practice, EarlyView.
Background Motor speech disorders are early, common, and functionally limiting features of atypical parkinsonian disorders (APDs) such as progressive supranuclear palsy (PSP), corticobasal syndrome (CBS), and multiple system atrophy (MSA). These impairments are underrecognized and undertreated in neurology clinics.
Federico Rodriguez‐Porcel, Farwa Ali, Michiko Bruno, Heather Davis Cuevas, Rohit Dhall, Kylie Dunne‐Platero, Lawrence I. Golbe, Ihtsham Haq, Nicole Herndon, Lawrence S. Honig, Kyurim Kang, Sarah Kremen, Guillaume Lamotte, Nikolaus R. McFarland, Michela Mir, Leila Montaser‐Kouhsari, Alexander Pantelyat, Joel Page, Hylan Pickett, Laura Purcell Verdun, Kelly Richardson, Jessica Shurer, Michelle Troche, Rene L. Utianski, Katya Villarreal‐Cavazos, Tuhin Virmani, Anne‐Marie Wills, as the Diagnosis and Treatment Working Group, CurePSP Center of Care (CoC) Network, Farwa Ali, Michiko Bruno, Timothy Chang, Rohit Dhall, Kimiko Domoto‐Reilly, Lawrence I. Golbe, Ihtsham Haq, Lawrence S. Honig, Sarah Kremen, Guillaume Lamotte, Zoltan Mari, Nikolaus R. McFarland, Leila Montaser‐Kouhsari, Alexander Pantelyat, Federico Rodriguez‐Porcel, Junaid Siddiqui, Jessica Shurer, Christopher Spears, Tuhin Virmani, Anne‐Marie Wills   +48 more
wiley   +1 more source

Digitizing collections to unlock the full potential of palynology: A case study with the Smithsonian palynology collection

PLANTS, PEOPLE, PLANET, EarlyView.
Large palynological collections have been built over decades and contain vital information. However, they are often difficult to access and use effectively. What is the point of having such collections if they are not fully utilizable? To solve this problem, we digitized the Smithsonian palynological collection using both light and confocal microscopy.
Carlos Jaramillo, Surangi W. Punyasena, Daurys de Alba, Roxana Alveo, Angelica Arcila, Jorge Bermudez, Jonatan Bustos, Dayenari Caballero‐Rodriguez, Karen Cardenas, David Caro, Francy Carvajal, Ivonne Marcela Castañeda, Shara Chaves, Carlos D'Apolito, Andres Diaz‐Jaramillo, Laura Diaz, Luisa Gomez, Mauricio León‐Carreño, Paula Lopera, Maria Alejandra Lopez, Priscila Lopez, Luke Mander, Jhonatan Martínez Murcia, Carlos Moreno, Enrique Moreno, Enrique Neyra, Brenda Orosco, Jhon Ortiz, Natalia Ossa, Natalia Ovalle, Carolina Ovalle, Angelo Plata, Ingrid Romero, Bruno Scudeiro, Silane A. F. da Silva Caminha, Axel Tejada‐Fajardo, Vinicius Do Valle, Thiago Wood   +37 more
wiley   +1 more source

Accelerating virtual patient generation with a Bayesian optimization and machine learning surrogate model

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 486-494, March 2025.
Abstract The pharmaceutical industry has increasingly adopted model‐informed drug discovery and development (MID3) to enhance productivity in drug discovery and development. Quantitative systems pharmacology (QSP), which integrates drug action mechanisms and disease complexities to predict clinical endpoints and biomarkers is central to MID3.
Hiroaki Iwata, Ryuta Saito
wiley   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Nanomedicine Meets Immunotherapy: Transforming Chimeric Antigen Receptor T Cell Treatment for Solid Tumors

Small Science, EarlyView.
This review highlights recent advances in nanomedicine that enhance chimeric antigen receptor (CAR) T cell therapy against solid tumors. It discusses key barriers to CAR T cell efficacy and outlines nanotechnology‐based strategies to improve tumor targeting, remodel the immunosuppressive microenvironment, and integrate nanomaterials into CAR T cell ...
Stephen O’Rourke, Nuo Xu, Hongjun Wang, Hexin Chen   +3 more
wiley   +1 more source

Longitudinal changes in peritoneal solute transport rate and the impact of lower glucose degradation product glucose dialysates

Therapeutic Apheresis and Dialysis, Volume 29, Issue 3, Page 471-478, June 2025.
Abstract Introduction Peritoneal solute transfer rates (PSTR) are reported to increase with time. Changes in PSTR were reviewed in long‐term peritoneal dialysis (PD) patients to determine whether lower glucose degradation products (low GDP) dialysates prevented an increase in PSTR. Methods PSTR was determined with a 4‐h peritoneal equilibrium test with
Andrew Davenport
wiley   +1 more source

Text mining for case report articles on “peritoneal dialysis” from PubMed database

Therapeutic Apheresis and Dialysis, Volume 29, Issue 3, Page 459-470, June 2025.
Abstract Introduction The number of published medical articles on peritoneal dialysis (PD) has been increasing, and efficiently selecting information from numerous articles can be difficult. In this study, we examined whether artificial intelligence (AI) text mining can be a good support for efficiently collecting PD information.
Kazuhiko Fukushima, Kenji Tsuji, Hiroyuki Nakanoh, Naruhiko Uchida, Soichiro Haraguchi, Shinji Kitamura, Jun Wada   +6 more
wiley   +1 more source

Improving police behavior through artificial intelligence: Pre‐registered experimental results in two large US agencies

Criminology, EarlyView.
Abstract Police body‐worn cameras (BWCs) generate extensive video data on officer behavior, yet resource constraints mean that only a fraction of this footage is ever reviewed. Recent advancements in artificial intelligence (AI) present an opportunity to automate these reviews, potentially influencing police conduct.
Ian T. Adams, Kyle McLean, Geoffrey P. Alpert   +2 more
wiley   +1 more source

Development and baseline findings of a national dataset describing Australian private practice dietetics

Nutrition &Dietetics, EarlyView.
Abstract Aims This study aimed to establish the processes for a national dataset describing Australian private practice dietetics and to report baseline workforce data. Methods A cross‐sectional survey captured workforce and business data for dietitians working in private practice dietetics in Australia.
Amy Kirkegaard, Olivia Wright, Peter Clark, Lauren Ball   +3 more
wiley   +1 more source

Peripheral blood biomarkers for predicting response to PD-1/PD-L1 inhibitors. [PDF]

Biomark Res
Chen S, Hu Y, Cheng H, Guo S, Han Y, Li K.   +5 more
europepmc   +1 more source