Results 161 to 170 of about 187,448 (328)

Higher sensitivity to ouabain‐induced toxicity in human induced pluripotent stem cell‐derived cardiomyocytes than human adult heart tissue despite similar Na+/K+‐ATPase pump current amplitudes

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Human induced pluripotent stem cell‐derived cardiomyocytes (hiPSC‐CM) have gained interest as a pharmacological model but their immaturity leads to uncertainty regarding translation. We studied the key player in maintaining ionic homeostasis, the Na+/K+‐ATPase (NKA), in hiPSC‐CM.
Djemail Ismaili, Paavo Virtanen, Junsoo Im, Paul Brunnbauer, Umber Saleem, Muhammed Ikbal Sönmez, Carl Schulz, Margaret Nandudu, Joris Winters, Cristina E. Molina, Johannes Petersen, Monika Stoll, Ulrich Schotten, Arne Hansen, Thomas Eschenhagen, Jussi T. Koivumäki, Torsten Christ   +16 more
wiley   +1 more source

Anterior to posterior preoperative risk assessment of abdominal thickness compared to BMI in ventral hernias. [PDF]

Hernia
Brosnihan PJ, Pihl ET, Reifel AE, Choi PK, Chen KT, Moazzez A, Ozao-Choy JJ.   +6 more
europepmc   +1 more source

Dark Current in the SAPHIRA Series of APD Arrays

, 2017
D. Atkinson, D. Hall, S. Jacobson, I. Baker   +3 more
semanticscholar   +1 more source

Variable electrophysiology before and after block of the two delayed rectifier potassium channels in groups of isolated rabbit ventricular cells

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Between‐cell differences in ventricular cardiomyocyte action potential duration (APD) and responses to ion channel block may contribute to pro‐arrhythmic dispersion of myocardial repolarisation. This study quantifies between‐cell physiological and pharmacological variability in the rabbit left ventricle (LV) and uses ...
Rebecca J. Gilchrist, Muhamad Hifzhudin Noor Aziz, Francis L. Burton, Radostin D. Simitev, Rachel C. Myles, Godfrey L. Smith   +5 more
wiley   +1 more source

Bacterial colonization of tumors drives immune activation and checkpoint blockade efficacy. [PDF]

Sci Rep
Rolig AS, Ziglari T, McGee GH, Kasiewicz MJ, Kolbaba K, Simons ND, Pucilowska J, Sfanos K, Redmond WL.   +8 more
europepmc   +1 more source

Transmural APD gradient synchronizes repolarization in the human left ventricular wall.

Cardiovascular Research, 2015
B. Boukens, M. Sulkin, C. Gloschat, F. Ng, E. Vigmond, I. Efimov   +5 more
semanticscholar   +1 more source

Buffering roles of financial resilience in navigating family stress and adolescent distress: A conditional process analysis

Family Relations, EarlyView.
Abstract Objective This study examined the buffering roles of financial resilience in serial mechanisms between family economic adversity and adolescent psychological distress. Background Resilience factors are assumed to buffer family stress processes, although previous studies have primarily discussed the psychological rather than financial aspects ...
Zewei Liu, Ji‐Kang Chen
wiley   +1 more source

Evaluation of Trilysine-Cross-Linked Gellan Gum for Intratumoral Delivery of Anti-PD-1 in a Colorectal Cancer Mouse Tumor Model. [PDF]

ACS Biomater Sci Eng
Villarreal-Otalvaro C, Luna F, Ramos Espinoza RA, Lombardini ED, Paxton Z, Vidali L, Coburn JM.   +6 more
europepmc   +1 more source

Removal of Different Classes of Uremic Toxins in APD vs CAPD: A Randomized Cross-Over Study

Peritoneal Dialysis International, 2015
S. Eloot, R. Vanholder, C. Dequidt, W. van Biesen   +3 more
semanticscholar   +1 more source

Social Representations of Bedside Milk Expression Among Mothers of Preterm Newborns in Neonatal Intensive Care Units

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To understand the social representations of bedside milk expression (BME) among mothers of preterm newborns in neonatal intensive care units (NICUs). Design Qualitative descriptive study. Methods The study was conducted from July to August 2024 in two NICUs of a referral maternity hospital in Fortaleza, Brazil.
Ana Karen de Sousa Alves, Ana Paula Melo Façanha, Elaine Meireles Castro, Keline Soraya Santana Nobre, Flávia Vasconcelos Teixeira, Maria Milena Farias de Souza Castro, José Mateus Pires, Victórya Suéllen Maciel Abreu, Priscila de Souza Aquino   +8 more
wiley   +1 more source