Results 241 to 250 of about 187,448 (328)

Synergistic Activation of Immunogenic Cell Death and the cGAS–STING Pathway by Engineered Zinc/Manganese‐Based Metal–Organic Framework Nanoplatforms for Colon Cancer Immunotherapy

Advanced Science, Volume 13, Issue 19, 2 April 2026.
A zinc/manganese (Zn/Mn)‐based metal‐organic framework (MOF) loaded with the STING agonist c‐di‐AMP diammonium (denoted AMP@Zn/Mn‐MOF) was developed to synergistically activate the cGAS‐STING pathway and induce immunogenic cell death. This nanoplatform reprograms the immunosuppressive tumor microenvironment, significantly enhancing anti‐PD‐L1 ...
Bingzi Zhu, Xiaodong Chen, Chang Xu, Xuehua Qian, Binglong Bai, Ji Lin, Wenhai Deng, Xiang Wang, Yuekai Cui, Shengsheng Zhao, Zuoliang Xie, Tao You, Yingpeng Huang, Xian Shen, Xufeng Lu, Weijian Sun   +15 more
wiley   +1 more source

Retrocochlear Auditory Dysfunctions (RADs) and Their Treatment: A Narrative Review. [PDF]

Audiol Res
Cuda D, Mancini P, Chiarella G, Santarelli R.   +3 more
europepmc   +1 more source

Documentation Optimization in Clinical Emergency Medicine (DOC‐EM)

AEM Education and Training, Volume 10, Issue 2, April 2026.
ABSTRACT Background High‐quality documentation is essential to patient care, billing accuracy, medicolegal protection, and effective communication in emergency medicine. Despite its importance, documentation training in graduate medical education remains inconsistent and infrequently assessed.
Jessica Baez, Heidi Sucharew, Meaghan Frederick   +2 more
wiley   +1 more source

Functional impact of long COVID among healthcare workers with comorbidities in Quebec, Canada: a cross-sectional study. [PDF]

BMJ Public Health
Isangwe S, Talbot D, Coutu MF, Canitrot E, Décary S, Falcone EL, Ouakki M, Latouche P, Piché A, Simard M, Balem M, De Serres G, Carazo S.   +12 more
europepmc   +1 more source

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

Advanced NanoBiomed Research, Volume 6, Issue 4, April 2026.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

A model for the human fetal ventricular myocyte electrophysiology. [PDF]

PLoS Comput Biol
Avezzú A, Longobardi S, Alvarez-Laviada A, Schultz F, Gorelik J, Williamson C, Niederer SA.   +6 more
europepmc   +1 more source

In Support of APD

The ASHA Leader, 2017
openaire   +1 more source

Species Distribution Modeling Reveals Future Climate Refugia and Important Areas for Rocky Plants in Brazil's Iron Quadrangle

Ecology and Evolution, Volume 16, Issue 4, April 2026.
Climate change is projected to sharply reduce suitable habitats for eight endemic rupestrian plant species in Brazil's Iron Quadrangle. Ensemble niche models reveal species‐specific vulnerabilities and highlight climatic refugia and corridors that may support persistence.
Ana Flávia Francisconi, João Victor da Silva Rabelo‐Araujo, Ana Cristina Silva Amoroso Anastacio, Ana Paula da Silva Marques, Maria Imaculada Zucchi   +4 more
wiley   +1 more source

Scleredema Associated With IgG/κ Monoclonal Gammopathy of Clinical Significance Successfully Treated With Daratumumab Monotherapy: A Case Report

eJHaem, Volume 7, Issue 2, April 2026.
ABSTRACT Background Cutaneous monoclonal gammopathy of clinical significance (MGCS) is rare and may present with scleredema‐like fibrosing skin disease. Case A 59‐year‐old man developed progressive induration of the upper body. Laboratory studies revealed an IgG/κ monoclonal protein, and skin biopsy showed dermal thickening with mucin deposition.
Davide Marcolongo, Alessandra Bressan, Elisabetta Zanatta, Mauro S. A. Alaibac, Ilaria Gianesello, Gianni Binotto, Laura Pavan, Angelo Paolo Dei Tos, Livio Trentin, Fabrizio Vianello   +9 more
wiley   +1 more source

Tissue preserving non-invasive physical plasma treatment for cervical squamous intraepithelial neoplasia grade 3-a prospective randomized, controlled clinical trial. [PDF]

Front Med (Lausanne)
Henes M, Matovina S, Rottscholl R, Feng YS, Fleischhacker A, Wang G, Enderle M, Awakowicz P, Brucker SY, Weiss M.   +9 more
europepmc   +1 more source