Results 71 to 80 of about 172,958 (331)

Prevalence of amyloid‐β pathology in distinct variants of primary progressive aphasia

Annals of Neurology, 2018
To estimate the prevalence of amyloid positivity, defined by positron emission tomography (PET)/cerebrospinal fluid (CSF) biomarkers and/or neuropathological examination, in primary progressive aphasia (PPA) variants.
David Bergeron, M. Gorno-Tempini, G. Rabinovici, M. Santos-Santos, W. Seeley, B. Miller, Y. Pijnenburg, M. A. Keulen, C. Groot, B. V. van Berckel, W. M. van der Flier, P. Scheltens, J. Rohrer, J. Warren, J. Schott, Nick C Fox, R. Sánchez-Valle, O. Grau‐Rivera, E. Gelpí, H. Seelaar, J. Papma, J. V. van Swieten, J. Hodges, C. Leyton, O. Piguet, E. Rogalski, M. Mesulam, L. Koric, Kristensen Nora, J. Pariente, B. Dickerson, I. Mackenzie, G. Hsiung, S. Belliard, D. Irwin, D. Wolk, M. Grossman, Matthew S. Jones, Jennifer Harris, D. Mann, J. Snowden, Patricio Chrem-Méndez, I. Calandri, A. Amengual, C. Miguet-Alfonsi, E. Magnin, G. Magnani, R. Santangelo, V. Deramecourt, F. Pasquier, N. Mattsson, C. Nilsson, O. Hansson, J. Keith, M. Masellis, S. Black, J. Matías-Guiu, M. Cabrera-Martín, C. Paquet, J. Dumurgier, M. Teichmann, M. Sarazin, M. Bottlaender, B. Dubois, C. Rowe, V. Villemagne, R. Vandenberghe, Elias D Granadillo, E. Teng, M. Mendez, P. Meyer, L. Frings, A. Lleó, R. Blesa, J. Fortea, S. Seo, J. Diehl-Schmid, T. Grimmer, K. Frederiksen, P. Sánchez-Juan, G. Chételat, Willemijn J Jansen, R. Bouchard, R. Laforce, P. Visser, R. Ossenkoppele   +85 more
semanticscholar   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

Overcoming barriers and embedding processes to sustainably deliver high-dose post-stroke aphasia rehabilitation: a mixed methods longitudinal process evaluation

BMC Health Services Research
Background Delivering evidence-based stroke rehabilitation in clinical practice is challenging due to intervention complexity and healthcare system factors.
Kirstine Shrubsole, Charlotte McCullough, Amy Chandler, Marie-Pier McSween, Rachel Levine, Kate O’Brien, David A. Copland, Jade Dignam   +7 more
doaj   +1 more source

Bridging the digital divide for people with aphasia: a study protocol for codesigning web accessibility tools and guidelines

BMJ Open
Introduction Aphasia is a language impairment that affects one-third of people who experience a stroke. Aphasia can impact all facets of language: speaking, understanding, reading and writing.
Leanne Togher, Jennifer Lee, S Alexander Haslam, Jessica Campbell, David A Copland, Sarah J Wallace, Ciara Shiggins, Kirstine Shrubsole, Bridget Burton, Peter Worthy, Ryan Deslandes, Phill Jamieson, Kim Barron, Annie Hill, Janet Wiles   +14 more
doaj   +1 more source

Noun and verb processing in aphasia: Behavioural profiles and neural correlates

NeuroImage: Clinical, 2018
The behavioural and neural processes underpinning different word classes, particularly nouns and verbs, have been a long-standing area of interest in psycholinguistic, neuropsychology and aphasiology research.
Reem S.W. Alyahya, Ajay D. Halai, Paul Conroy, Matthew A. Lambon Ralph   +3 more
doaj   +1 more source

Hippocampal diaschisis contributes to anosognosia for hemiplegia: Evidence from lesion network-symptom-mapping

NeuroImage, 2020
Anosognosia for hemiplegia (AHP) is known to be associated with lesions to the motor system combined with varying lesions to the right insula, premotor cortex, parietal lobe or hippocampus.
Julian Klingbeil, Max Wawrzyniak, Anika Stockert, Hans-Otto Karnath, Dorothee Saur   +4 more
doaj   +1 more source

Treatment fidelity monitoring, reporting and findings in a complex aphasia intervention trial: a substudy of the Very Early Rehabilitation in SpEech (VERSE) trial

Trials, 2022
Background Treatment fidelity is inconsistently reported in aphasia research, contributing to uncertainty about the effectiveness of types of aphasia therapy following stroke.
Erin Godecke, Emily Brogan, Natalie Ciccone, Miranda L. Rose, Elizabeth Armstrong, Anne Whitworth, Fiona Ellery, Audrey Holland, Sandy Middleton, Tapan Rai, Graeme J. Hankey, Dominique Cadilhac, Julie Bernhardt   +12 more
doaj   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

The behavioural patterns and neural correlates of concrete and abstract verb processing in aphasia: A novel verb semantic battery

NeuroImage: Clinical, 2018
Typically, processing is more accurate and efficient for concrete than abstract concepts in both healthy adults and individuals with aphasia. While, concreteness effects have been thoroughly documented with respect to noun processing, other words classes
Reem S.W. Alyahya, Ajay D. Halai, Paul Conroy, Matthew A. Lambon Ralph   +3 more
doaj   +1 more source

The Tale of the Residual Tail: Insights From Continuous Intracranial Monitoring From Post‐Hippocampectomy Dynamics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Subtotal hippocampal resection can leave residual hippocampal tissue, yet the immediate postoperative electrophysiologic evolution of such remnants is unknown. We describe a patient with drug‐resistant temporal lobe epilepsy in whom a hippocampal remnant was continuously monitored using a responsive neurostimulator (RNS) following subtotal ...
Patrick Hartnett, Syeda Amrah Hashmi, Amaan Qureshi, Heather Spader, Shayan Moosa, Ifrah Zawar   +5 more
wiley   +1 more source