Results 101 to 110 of about 6,575 (292)

Nutritional aphrodisiacs: Biochemistry and Pharmacology

open access: yesCurrent Research in Food Science
In 2022, the global prevalence of erectile dysfunction (ED) was estimated to be at least 150 million cases. This number is greatly suspected to be underestimate as most men withhold information about ED. Also, about 15% of world population have infertility troubles, and male factors are responsible for almost half of these cases.
Haitham Al-Madhagi   +1 more
openaire   +3 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Ethnomedicine for aphrodisiac by the tribes of North Coastal Andhra Pradesh [PDF]

open access: yes, 2019
The aim of the present study was to document aphrodisiac plants used by the tribes of North Coastal Andhra Pradesh.It resulted in discovering 45 species of plants covering 45 genera and 35 families used as aphrodisiac.
Reddi, T. V. V. Seetharami; Department of Botany, Andhra University, Visakhapatnam, Andhra Pradesh   +1 more
core   +3 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Aphrodisiac Activity of the Aqueous Crude Extract of Purple Corn () in Male Rats

open access: yesJournal of Evidence-Based Complementary & Alternative Medicine, 2017
In the present study, the aphrodisiac properties of the purple corn ( Zea mays ) in male rats were analyzed. The aqueous crude extract of purple corn (at 25, 50, and 75 mg/kg) was administered to ( a ) copulating male rats and ( b ) anesthetized and ...
Miguel Carro-Juárez PhD   +3 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Scientific Validation of South African Aphrodisiac Plants for Erectile Dysfunction: An Exploratory Review

open access: yesNatural Product Communications
Erectile dysfunction (ED) is a global public health issue affecting approximately 150 million men of all ages. The ED prevalence in South Africa is 65% of adult males attending a primary care facility.
Thiambi R. Netshiluvhi
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Accidental poisoning after ingestion of "aphrodisiac" berries: Diagnosis by analytical toxicology

open access: yes, 2012
Background: A large number of plants, seeds, and berries have been used for medicinal, psychotropic, or aphrodisiac purposes for a thousand years. Mandragora officinarum belongs to the family of Solanaceae and is traditionally known as an aphrodisiac and
Maravelias, C.   +6 more
core   +1 more source

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