Results 81 to 90 of about 6,575 (292)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Cumulative Effects of Constituents from the Mushroom Calvatia nipponica on the Contractility of Penile Corpus Cavernosum Smooth Muscle

Mycobiology, 2020
Calvatia nipponica, a puffball mushroom (Agaricaceae), is thought to be an aphrodisiac, as this mushroom is traditionally known to improve sexual function in males.
Seulah Lee, Min-Ji Kim, Bum Soo Lee, Rhim Ryoo, Hye Kyung Kim, Ki Hyun Kim   +5 more
doaj   +1 more source

Aphrodisiac foods: bibliographic survey of national scientific production

, 2020
Objective: Objective: To outline general profiles of national scientific production about aphrodisiac foods. Methods: We proceeded through a bibliographic survey with a qualitative approach in periodicals with access considering the period from 2004 to ...
Oliveira, Luziane Bastos de
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Screening of aphrodisiac property in sea slug, Aplysia dactylomela [PDF]

, 2014
ObjectiveTo evaluate the aphrodisiac property of Aplysia dactylomela (A. dactylomelan), locally known as ‘dugu-dugu’, which is one of the sea slug species.MethodsTwo types of extractions were used; aqueous and lipid. Three doses of each A.
Mohd Roslan, Noor Atika Elliyana, Mohd Daud, Jamaluddin, Roslan, Noor Atika Elliyana Mohd, Hashim, Ridzwan, Daud, Jamaluddin Mohd, Zulkipli, Farah Hanis   +5 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

The Pharmaceutical Properties, Microbial Quality, In-vivo Aphrodisiac Effect and Safety of Some Herbal Bitters Sold in Southwest Nigeria [PDF]

, 2020
Aphrodisiac drugs are used to enhance sexual activity and rectify erectile dysfunction especially among older men. In Nigeria, herbal medicinal products formulated as herbal drinks/bitters are prevalent and sold in various locations including motor parks,
Afolabi, J.M, Oyagbemi, A.A, Ajala, T.O, Oyeyemi, M.O, Dike, D.N, Odeku, O.A   +5 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source