Results 91 to 100 of about 1,204,736 (293)

High-Titer Recombinant Adenovirus 26 Vector GMP Manufacturing in HEK 293 Cells with a Stirred Single-Use Bioreactor for COVID-19 Vaccination Purposes

ACS Omega, 2023
Hossein Sedighikamal, Alireza Sattarzadeh, Reza Karimi Mostofi, Behnoush Dinarvand, Madineh Nazarpour   +4 more
doaj   +1 more source

When is it Biased? Assessing the Representativeness of Twitter's Streaming API [PDF]

, 2014
Twitter has captured the interest of the scientific community not only for its massive user base and content, but also for its openness in sharing its data. Twitter shares a free 1% sample of its tweets through the "Streaming API", a service that returns
Liu, Huan, Morstatter, Fred, Pfeffer, Jürgen   +2 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

The elephants for King Leopold: a curious experiment in Colonial Africa

Гуманитарные и юридические исследования
Introduction. The article is devoted to the subject of the colonial history of Africa, little-discussed in Russian historiography, – the attempt of the Belgians in the Congo to use elephants in the development of hard-to-reach areas, following the ...
A. A. Abakumov
doaj   +1 more source

Incrementally Computing Minimal Unsatisfiable Cores of QBFs via a Clause Group Solver API

, 2015
We consider the incremental computation of minimal unsatisfiable cores (MUCs) of QBFs. To this end, we equipped our incremental QBF solver DepQBF with a novel API to allow for incremental solving based on clause groups. A clause group is a set of clauses
A Belov, A Biere, A Cimatti, A Ignatiev, A Nadel, A Nadel, C Miller, E Giunchiglia, F Lonsing, F Lonsing, G Audemard, H Kleine Büning, J Marques-Silva, J-M Lagniez, L Zhang, M Benedetti, M Cadoli, MH Liffiton, N Dershowitz, N Eén, N Eén, R Asín, R Letz, T Jussila, U Egly   +24 more
core   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Discovery of a Novel Diterpene in Brown Propolis from the State of Parana, Brazil

Natural Product Communications, 2016
Propolis is a resinous substance collected by honeybees from certain plant sources. The components of propolis depend on the vegetation of the area in which apiculture is practiced.
Shigemi Tazawa, Yasuko Arai, Sho Hotta, Taichi Mitsui, Hiroshi Nozaki, Kenji Ichihara   +5 more
doaj   +1 more source

APIs

, 2023
Una API, o Interfaz de Programación de Aplicaciones (por sus siglas en inglés, Application Programming Interface), es un conjunto de reglas y protocolos que permiten que diferentes aplicaciones o sistemas informáticos se comuniquen entre sí. En otras palabras, una API define los métodos y datos que las aplicaciones pueden utilizar para interactuar unas
openaire   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Development of a Manufacturing Process toward the Convergent Synthesis of the COVID-19 Antiviral Ensitrelvir

ACS Central Science, 2023
Takahiro Kawajiri, Akihito Kijima, Atsuhiro Iimuro, Eisaku Ohashi, Katsuya Yamakawa, Kazushi Agura, Kengo Masuda, Kensuke Kouki, Koji Kasamatsu, Shuichi Yanagisawa, Sho Nakashima, Setsuya Shibahara, Takashi Toyota, Takafumi Higuchi, Takahiro Suto, Tadashi Oohara, Toshikatsu Maki, Naoto Sahara, Nobuaki Fukui, Hisayuki Wakamori, Hidaka Ikemoto, Hiroaki Murakami, Hiroyasu Ando, Masahiro Hosoya, Mizuki Sato, Yusuke Suzuki, Yuta Nakagawa, Yuto Unoh, Yoichi Hirano, Yoshitomo Nagasawa, Satoshi Goda, Takafumi Ohara, Takayuki Tsuritani   +32 more
doaj   +1 more source