Results 71 to 80 of about 381,033 (292)

VariantEffect/mavedb-api: v2024.1.0

<h2>What's Changed</h2> <ul> <li>Bugfix: Possible to Create Score Sets with No Targets by @bencap in https://github.com/VariantEffect/mavedb-api/pull/185</li> <li>Ensure Response for Experiment Deletion is NoneType by @
jstone-uw, ashsny, Alan Rubin, EstelleDa, harmatt, Benjamin Capodanno, Nick Moore   +6 more
core   +1 more source

VariantEffect/mavedb-api: v2023.4.2

, 2023
<h2>What's Changed</h2> <ul> <li>Update README.md to add reference to MaveDB paper by @ashsny in https://github.com/VariantEffect/mavedb-api/pull/103</li> <li>Release 2023.4.2.
jstone-uw, ashsny, Alan Rubin, EstelleDa, harmatt, Benjamin Capodanno   +5 more
core   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Governify for APIs: SLA-driven ecosystem for API governance

Proceedings of the 2019 27th ACM Joint Meeting on European Software Engineering Conference and Symposium on the Foundations of Software Engineering, 2019
As software architecture design is evolving to a microservice paradigm, RESTful APIs are being established as the preferred choice to build applications. In such a scenario, there is a shift towards a growing market of APIs where providers offer different service levels with tailored limitations typically based on the cost.
Antonio Gamez-Diaz, Pablo Fernandez 0001, Antonio Ruiz-Cortés   +2 more
openaire   +4 more sources

EOSC-synergy/sqaaas-api-server: 2.8.1

, 2022
Full Changelog: https://github.com/EOSC-synergy/sqaaas-api-server/compare/2.7.1...2.8.
orviz, Alvaro Lopez Garcia
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

NASA-PDS/registry-api: registry-api v1.5.0-SNAPSHOT

Web API service for the PDS Registry, providing the implementation of the PDS Search API (https://github.com/nasa-pds/pds-api) for the PDS ...
TESTPERSONAL, thomas loubrieu, Sean Kelly, PDSEN CI Bot, Jimmie Young, Lyle Barner, Eugene, al-niessner, Alex Dunn, Jordan Padams, Catherine Suh   +10 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

K-CAI NEURAL API v0.1.6

, 2021
K-CAI NEURAL API is a Keras based neural network API that will allow you to prototype faster! From version v0.1.6, the new function cai.datasets.save_tfds_in_format saves a TensorFlow dataset as image files.
Joao Paulo Schwarz Schuler
core   +1 more source