Results 51 to 60 of about 201,051 (250)
Human Intestinal Organoids As Models to Study Enteric Bacteria and Viruses [PDF]
, 2023 Laboratory studies of host-microbe interactions have historically been carried out using transformed cell lines and animal models. Although much has been learned from these models, recent advances in the development of multicellular, physiologically ...
Adeniyi-Ipadeola, Grace +2 more
core +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Applied SciencesBackground/Objectives: The primary purpose of the study is to investigate the bond strength of apical fillings following retreatment in teeth with failed apical resection.
Sevda Tok, Leyla Benan Ayranci
doaj +1 more source
Studies on factors influencing the vegetative propagation in walnut (Juglans regia L. )
Journal of Horticultural Sciences, 2018 The experiment was carried out to examine the effect ofdifferent status of physiologically resting scion wood,environment and grafting time for maximum graft success in walnut.
S R Singh +3 more
doaj +1 more source
Topographic Evaluation of Apex and Root Canal of Maxillary Premolars in an Iranian Population
Journal of Dental School, 2020 Objective: Knowledge about the internal anatomy of the root canal and apical foramen is a critical prerequisite for root canal therapy and is necessary for the success of endodontic treatment. This study aimed to determine the distance of apical foramen
Mandana Naseri +2 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular biosignatures and gut-barrier alterations in inflammatory bowel diseases [PDF]
, 2022 Inflammatory bowel diseases (IBD) are chronic immune-mediated disorders affecting the gastrointestinal tract. The multifactorial pathophysiology of IBD is commonly explained as an abnormal interplay between genetic, immune, environmental and microbial ...
Moraes Holst, Luiza
core +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Sorbin and SH3 domain-containing protein 2 (SORBS2) is a component of the acto-myosin ring at the apical junctional complex in epithelial cells. [PDF]
PLoS ONE, 2017 SORBS2 is a scaffolding protein associated with Abl/Arg non-receptor tyrosine kinase pathways and is known to interact with actin and several other cytoskeletal proteins in various cell types.
Karin Fredriksson-Lidman +3 more
doaj +1 more source
Establishment of intestinal organoids from small intestine of growing cattle (12 months old)
Journal of Animal Science and Technology, 2022 Recently, we reported the robust in vitro three-dimensional (3D) expansion of intestinal organoids derived from adult bovine (> 24 months) samples. The present study aimed to establish an in vitro 3D system for the cultivation of intestinal organoids ...
Kang Won Park +9 more
doaj +1 more source