Results 61 to 70 of about 201,051 (250)
Chemically Defined Organoid Culture System for Cholangiocyte Differentiation [PDF]
Cholangiocyte organoids provide a powerful platform for applications ranging from in vitro modeling to tissue engineering for regenerative medicine. However, their expansion and differentiation are typically conducted in animal-derived hydrogels, which ...
Masereeuw, Rosalinde +5 more
core +2 more sources
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Clinical Case Reports, 2019 Key Clinical Message Contrast‐enhanced echocardiography or cardiac magnetic resonance imaging is of value in the diagnosis of apical hypertrophic cardiomyopathy.
Jonathan Al‐Saadi +3 more
doaj +1 more source
Assessing the Physical and Immune Response of Intestinal Organoids for Necrotizing Enterocolitis using NEC-in-a-Dish [PDF]
, 2023 Necrotizing enterocolitis (NEC) is a devastating disease that impacts the intestinal tract, which most commonly occurs in preterm infants. Its pathogenesis is unknown, but previous studies have found that an alteration in the intestinal microbiome, in ...
Melbouci, Eve
core +2 more sources
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Journal of Indian Society of Pedodontics and Preventive Dentistry, 2016 Context: Reduction of the bacterial populations to levels compatible with periradicular tissue healing is the primary microbiological goal of the endodontic treatment of teeth with apical periodontitis.
Sneha Bharatkumar Bharuka +1 more
doaj +1 more source
Development of a New 3D Hybrid Model for Epithelia Morphogenesis
Frontiers in Bioengineering and Biotechnology, 2020 Many epithelial developmental processes like cell migration and spreading, cell sorting, or T1 transitions can be described as planar deformations. As such, they can be studied using two-dimensional tools and vertex models that can properly predict ...
Filippos Ioannou +8 more
doaj +1 more source
Engineering a microwell duct-on-chip technology to translate exocrine pancreatic organoids to a cancer model [PDF]
, 2022 Das duktale Adenokarzinom der Bauchspeicheldrüse (PDAC) ist eine der tödlichsten Erkrankungen der exokrinen Bauchspeicheldrüse, für die uns relevante Frühdiagnosemarker fehlen.
Wiedenmann, Sandra
core
Bistable Mechanisms 3D Printing for Mechanically Programmable Vibration Control
Advanced Engineering Materials, EarlyView.This work introduces a 3D‐printed bistable mechanism integrated into tuned mass dampers (TMDs) for mechanically adaptive passive vibration suppression. Through optimized geometry, the bistable design provides adaptable vibration reduction across a broad range of scenarios, achieving effective vibration mitigation without complex controls or external ...
Ali Zolfagharian +4 more
wiley +1 more source
Rebalancing of mitochondrial homeostasis through an NAD+-SIRT1 pathway preserves intestinal barrier function in severe malnutrition. [PDF]
, 2023 BACKGROUND: The intestine of children with severe malnutrition (SM) shows structural and functional changes that are linked to increased infection and mortality. SM dysregulates the tryptophan-kynurenine pathway, which may impact processes such as SIRT1-
Arvidsson Kvissberg, Matilda E +27 more
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