Results 81 to 90 of about 201,051 (250)

Transmissible gastroenteritis virus induces inflammatory responses via RIG-I/NF-κB/HIF-1α/glycolysis axis in intestinal organoids and in vivo. [PDF]

peer reviewed[en] UNLABELLED: Transmissible gastroenteritis virus (TGEV)-induced enteritis is characterized by watery diarrhea, vomiting, and dehydration, and has high mortality in newborn piglets, resulting in significant economic losses in the pig ...
Cai, Yifei, Fu, Yuguang, Li, Yang, Liu, Guangliang, Liu, Yuanyuan, Rui, Xue, Tan, Chen, Yang, Ning, Zhang, Yunhang   +8 more
core   +1 more source

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

Development of robust antiviral assays using relevant apical-out human airway organoids

AbstractWhile breakthroughs with organoids have emerged as next-generationin vitrotools, standardization for drug discovery remains a challenge. This work introduces human airway organoids with reversed biopolarity (AORBs), cultured and analyzed in a high-throughput, single-organoid-per-well format, enabling milestones towards standardization.
Ji-Hoon Lee, Julia C. LeCher, Eric Parigoris, Noriyuki Shinagawa, Jason Sentosa, Candela Manfredi, Shu Ling Goh, Ramyani De, Sijia Tao, Keivan Zandi, Franck Amblard, Eric J. Sorscher, Jason R. Spence, Rabindra Tirouvanziam, Raymond F. Schinazi, Shuichi Takayama   +15 more
openaire   +2 more sources

A 3D Biofabricated Disease Model Mimicking the Brain Extracellular Matrix Suitable to Characterize Intrinsic Neuronal Network Alterations in the Presence of a Breast Tumor Disseminated to the Brain

Advanced Functional Materials, EarlyView.
A 3D disease model is developed using customized hyaluronic‐acid‐based hydrogels supplemented with extracellular matrix (ECM) proteins resembling brain ECM properties. Neurons, astrocytes, and tumor cells are used to mimic the native brain surrounding.
Esra Türker, Mateo S. Andrade Mier, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Christian Stigloher, Nicoletta Murenu, Natascha Schaefer, Jörg Tessmar, Gregor Lang, Silvia Budday, Katrin G. Heinze, Antje Appelt‐Menzel, Pamela L. Strissel, Reiner Strick, Carmen Villmann   +16 more
wiley   +1 more source

Peptide Sequencing With Single Acid Resolution Using a Sub‐Nanometer Diameter Pore

Advanced Functional Materials, EarlyView.
To sequence a single molecule of Aβ1−42–sodium dodecyl sulfate (SDS), the aggregate is forced through a sub‐nanopore 0.4 nm in diameter spanning a 4.0 nm thick membrane. The figure is a visual molecular dynamics (VMD) snapshot depicting the translocation of Aβ1−42–SDS through the pore; only the peptide, the SDS, the Na+ (yellow/green) and Cl− (cyan ...
Apurba Paul, Archith Rayabharam, Lisa Almonte, Eveline Rigo, Joshy Joseph, Ashutosh Kumar, Zhuxin Dong, Narayana Aluru, Gregory Timp   +8 more
wiley   +1 more source

Morphology, Evolution, and Host Associations of Bee-Associated Mites of the Family Chaetodactylidae (Acari: Astigmata) with a monographic revision of North American taxa [PDF]

, 2008
http://deepblue.lib.umich.edu/bitstream/2027.42/110995/1/Bee Mites.pdfDescription of Bee Mites.pdf : Main ...
Klimov, Pavel B, OConnor, Barry M.
core  

Synergistic Fluorine and Cyanide Co‐Modification to Reinforce Photoinduced Excitons Formation and Transfer for Efficient CO2 Photoreduction

Advanced Functional Materials, EarlyView.
An advanced F‐doped and ─CN group co‐modified FCCN is developed. Due to the synergistic effects of co‐modification in promoting photogenerated exciton generation, enhancing charge kinetics, expanding active interfacial areas, and optimizing CO2 interfacial reactions, the FCCN photocatalyst demonstrates excellent catalytic performance and high ...
Sheng‐Qi Guo, Qingqing Dong, Xiaodong Sun, Ziqi Zhang, Linda Wang, Lei Bao, Bozhan Li, Hui Li, Yanrui Li, Tianyi Ma   +9 more
wiley   +1 more source

Apical Root Resorption after Orthodontic Treatment

Česká Stomatologie a Praktické Zubní Lékařství, 2012
Aim: The aim of the present study was to assess the incidence of apical root resorption in patients treated with fixed orthodontic appliances and find out whether the frequency of their occurrence depends on sex, patient's age, Angle class malocclusion ...
P. Černochová, L. Izakovičová Hollá
doaj   +1 more source

Electrochemical Formation of BiVO4/BiPO4 Photoanodes for Enhanced Selectivity toward H2O2 Generation

Advanced Functional Materials, EarlyView.
In acidic KPi, V dissolves from the BiVO4 lattice, while adsorbed phosphate reacts with the electrode under an external bias, forming a BiPO4 surface layer. This BiPO4 layer exhibits stronger bicarbonate adsorption, redirecting the water oxidation pathway toward two‐electron H2O2 production.
Kaijian Zhu, Xinyi Zhang, Lan Wen, Hongjiang Chen, Yudhistira Tirtayasri Amrillah, Vivi Fauzia, Hongzhen Dong, Shaoqiang Su, Wenjun Luo, Ferry Anggoro Ardy Nugroho, Patrick H.‐L. Sit, Yun Hau Ng, Fatwa F. Abdi   +12 more
wiley   +1 more source

Outcome assessment of apical surgery: A study of 234 teeth

Journal of the Formosan Medical Association, 2019
Background/Purpose: Apical surgery is an option for management of endodontically-treated tooth with persistent periapical lesions or symptom and sign.
Wan-Chuen Liao, Yuan-Ling Lee, Yi-Ling Tsai, Hseuh-Jen Lin, Mei-Chi Chang, Shu-Fang Chang, Shu-Hui Chang, Jiiang-Huei Jeng   +7 more
doaj   +1 more source