Apical-Out Human Airway Organoids Modeling SARS-CoV-2 Infection [PDF]
The respiratory epithelium, particularly the airway epithelium, is the primary infection site for respiratory pathogens. The apical surface of epithelial cells is constantly exposed to external stimuli including invading pathogens. Efforts have been made
Man Chun Chiu +8 more
doaj +3 more sources
Preferential apical infection of Caco-2 intestinal cell monolayers by SARS-CoV-2 is associated with damage to cellular barrier integrity: Implications for the pathophysiology of COVID-19. [PDF]
SARS-CoV-2 can infect different organs, including the intestine. In an in vitro model of Caco-2 intestinal cell line, we previously found that SARS-CoV-2 modulates the ACE2 receptor expression and affects the expression of molecules involved in ...
Clémence Garrec +6 more
doaj +2 more sources
Intestinal epithelial cell interactions with enteric pathogens have been incompletely elucidated owing to the lack of model systems that recapitulate the cellular diversity, architecture and functionality of the intestine.
Miaomiao Yan +8 more
doaj +2 more sources
A Comparative Study of Radiography and Computed Tomography in Detecting Periapical Infections in Alpacas (Vicugna pacos) [PDF]
Alpacas are frequently affected by dental pathologies, with periapical infection of the cheek teeth being a significant concern. While radiography is commonly used as the primary diagnostic imaging modality, it has known limitations, particularly due to ...
Linda Rutigliano +4 more
doaj +2 more sources
Endodontic Surgery Management of a Large Periradicular Actinomycosis Lesion [PDF]
A 22-year-old female patient consulted the Odontology Department of the Mohammed V Military Hospital in Rabat, Morocco, for a recurrent abscess in relation to the left maxillary central incisor (#21).
Rahhali Mohamed +2 more
doaj +2 more sources
Apical-out bovine intestinal organoids as an infection model for Cryptosporidium parvum
Cryptosporidium parvum is a major pathogen responsible for neonatal calf diarrhoea, but research has been hampered due to the lack of in vitro models that can complete the life cycle.
Mathilde Svensen Varegg +4 more
doaj +2 more sources
Apical Hypertrophic Cardiomyopathy and Hepatitis C Virus Infection
The familial form of hypertrophic cardiomyopathy (HCM) is attributed to mutations in the genes for contractile proteins, but the etiology of non-familial form remains unknown. This study was designed to examine the clinical features, histopathologic changes, and hepatitis C virus (HCV) genomes in patients with HCM associated with HCV infection.
A, Matsumori +9 more
openaire +4 more sources
Apical hypertrophic cardiomyopathy associated with HCV infection
A case is reported of a female patient with apical hypertrophic cardiomyopathy with negative chest T waves associated with HCV infection.
Viktor Viktorovich Fomin +11 more
doaj +3 more sources
APIC 2017 to feature hot topics in infection prevention [PDF]
openaire +3 more sources
BackgroundOral health in alpacas is often neglected until severe dental disease becomes evident under the form of a pronounced mandibular swelling with or without fistulation.
Kirsten Proost +2 more
doaj +1 more source

