Results 111 to 120 of about 1,848,273 (305)
Advanced Science, EarlyView.A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung +15 more
wiley +1 more source
Subcutaneous Infection Caused by Corynespora Cassiicola, a Plant Pathogen
, 2011 We describe a 69-year-old female farmer with diabetes mellitus who developed subcutaneous infection due to a plant pathogen, Corynespora cassiicola. The organism was identified based on characteristic morphotypes and confirmed by sequence analysis of the
LIU, CHUN-ENG;LIOU, JIA-HUNG;HSIUE, HAN-CHUNG;HSIAO, CHENG-HSIANG;HSUEH, PO-REN +1 more
core +1 more source
Advanced Science, EarlyView.Pathological tissue rigidity mechanoprimes microglia by enhancing actin cytoskeleton–nucleus coupling and chromatin opening at rigidity‐responsive cis‐regulatory elements (mechanoCREs). Subsequent NF‐κB/p65 signaling converges on this permissive regulatory state to amplify inflammatory gene expression and microglial activation.
Yu Xuan Meng +15 more
wiley +1 more source
Polar release of pathogenic Old World hantaviruses from renal tubular epithelial cells
Virology Journal, 2012 Background Epithelio- and endotheliotropic viruses often exert polarized entry and release that may be responsible for viral spread and dissemination. Hantaviruses, mostly rodent-borne members of the Bunyaviridae family infect epithelial and endothelial ...
Krautkrämer Ellen +3 more
doaj +1 more source
35 LLLT IN THE TREATMENT OF PERI-APICAL INFECTION
Photodiagnosis and Photodynamic Therapy, 2008 short laser pulses for clinical indications as well as industrial implementation of medical devices including a discussion of scanning algorithms and necessary pulse durations. Material and Methods: Different scanning algorithms were simulated in a mathematical simulation (MatLab) and verified in in-vitro experiments on human dentine slices regarding ...
D.R. Vieru, A.S. Dumitriu
openaire +1 more source
, 2011 Clin Microbiol Infect ABSTRACT: Patients with pulmonary tuberculosis (TB) can be simultaneously infected with different strains of Mycobacterium tuberculosis (mixed infection). We investigated the prevalence and risk factors of mixed infection by Beijing
王振源;許翰琳;余明治;江振源;余忠仁;李麗娜;楊泮池 +1 more
core +1 more source
Advanced Science, EarlyView.High‐throughput Differential Dynamic Microscopy measures frequency‐resolved mechanical fingerprints from 3 to 10 μL$\umu{\rm L}$ mucus samples using only a few minutes of operator attention per sample. This automated analysis enables scalable mucus phenotyping for translational research by distinguishing mechanical heterogeneity among donors, disease ...
Feng Ling +18 more
wiley +1 more source
Integrated Management Of Implant Apical Infection And Adjacent Lesions
International Dental JournalIntroduction: Implant apical infections may spread to adjacent teeth, requiring multidisciplinary intervention. This case demonstrates the retention of an infected implant (31) with concurrent periapical lesions in tooth 32 through combined surgical and ...
Feng Chen, Yang Lin
doaj +1 more source
Avaliação da infiltração cervico-apical, par meio de microorganismos, atraves de canais radiculares obturados por tecnicas da guta-percha termoplastificada e condensação lateral : estudo in vitro [PDF]
, 1998 Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro de Ciencias da SaudeEste estudo avaliou in vitro o selamento, no sentido cérvico-apical, de canais radiculares obturados pela técnica de condensação lateral de cones de guta-percha ...
Lucena, Marcia Gonçalves
core
Nuclear IDH3A Drives Transcriptional Programs in Melanoma via the YBX1–JUN/FOS Axis
Advanced Science, EarlyView.Genomic amplification drives aberrant nuclear localization of IDH3A in melanoma. Independent of its canonical metabolic activity, nuclear IDH3A cooperates with YBX1 to activate the c‐JUN/c‐FOS transcriptional program, while NONO facilitates its nuclear localization.
Juan Ran +10 more
wiley +1 more source