Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Adenylyl cyclase alpha and cAMP signaling mediate Plasmodium sporozoite apical regulated exocytosis and hepatocyte infection. [PDF]
Malaria starts with the infection of the liver of the host by Plasmodium sporozoites, the parasite form transmitted by infected mosquitoes. Sporozoites migrate through several hepatocytes by breaching their plasma membranes before finally infecting one ...
Takeshi Ono +10 more
doaj +1 more source
Comparação da capacidade de dois localizadores apicais eletrônicos de determinar o limite apical da instrumentação endodôntica: estudo ex vivo [PDF]
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.O objetivo deste trabalho foi avaliar a capacidade de dois aparelhos eletrônicos localizarem o forame e a constrição apical, limites considerados ...
Klasener, Martha
core
Moderate effect of artemisinin-based combination therapy on transmission of plasmodium falciparum [PDF]
Background. Artemisinin-based combination therapy (ACT) reduces microscopically confirmed gametocytemia and mosquito infection. However, molecular techniques have recently revealed high prevalences of submicroscopic gametocytemia.
Sauerwein, Robert W +30 more
core +1 more source
This review examines passive, active, and hybrid liquid manipulation strategies, highlighting hybrid approaches as an emerging route to reconcile energy efficiency with adaptive control. By actively reconstructing passive surfaces to store programmable interfacial energy, hybrid systems enable flexible yet low‐power liquid transport, with perspectives ...
Jiaqi Miao +3 more
wiley +1 more source
Endomyocardial fibrosis presenting as apical calcification and infective endocarditis [PDF]
A 46-year-old woman was admitted for suspected infective endocarditis. Echocardiography showed a mobile mass attached to the thickened endocardium of the left ventricular apex. Histological examination showed extensive endomyocardial fibrosis.
Aikawa, Tadao +3 more
openaire +4 more sources
A collagen‐based gut‐on‐chip model replicates the intestinal extracellular matrix, supporting villi‐like structures, tight junctions, and mucin production. This biomimetic platform enables rapid epithelial differentiation and functional barrier formation.
Fernanda López García +4 more
wiley +1 more source
Evidence suggests that diabetic patients are more significantly affected by problems of endodontic origin. This study sought to radiographically and histologically examine the development of periradicular inflammation in control and in diabetic rats ...
Luci Armada-Dias +6 more
doaj +1 more source
“Hormonal crosstalking in the control of apical dominance in pea (Pisum sativum L.)” [PDF]
The aim of my research is the study of the involvement of three plant growth regulators (Auxin, Gibberellins and Strigolactones) in the regulation of apical dominance in pea and how they interact to control lateral bud growth.
LUISI, ALESSANDRO
core
Immunoglobulin G antibodies to merozoite surface antigens are associated with recovery from chloroquine-resistant Plasmodium falciparum in Gambian children. [PDF]
We examined the hypothesis that recovery from uncomplicated malaria in patients carrying drug-resistant Plasmodium falciparum is a measure of acquired functional immunity and may therefore be associated with humoral responses to candidate vaccine ...
Jamila Ismaili +26 more
core +2 more sources

