Results 41 to 50 of about 1,026 (88)

Universal and Lineage‐Specific Patterns in the Distribution of ECOD Domain Homology Groups Across Superkingdoms

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 10, Page 1644-1657, October 2026.
ABSTRACT Proteins are built from modular domains that serve as fundamental units of structure and evolution. While individual domains have been extensively cataloged, their collective distribution across the lineages of life has remained poorly resolved.
Rui Guo, Jimin Pei, Jing Zhang, Qian Cong, Nick V. Grishin, R. Dustin Schaeffer   +5 more
wiley   +1 more source

Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 10, Page 1686-1701, October 2026.
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva, Monique Mantovani, Maria E. S. D. Lino, Aline O. Albuquerque, João H. M. da Silva, Ronaldo A. P. Nagem, Adriana L. Rojas, Geraldo R. Sartori, Eduardo Horjales, David Campbell, Otavio H. Thiemann   +10 more
wiley   +1 more source

Comparative Immunopathology of Toxoplasma gondii Natural Infections in Marmosets (Callithrix spp.) and Howler Monkeys (Alouatta spp.), Brazil

Journal of Medical Primatology, Volume 55, Issue 5, October 2026.
ABSTRACT Introduction Neotropical primates (NTPs) present varying susceptibility to toxoplasmosis caused by Toxoplasma gondii, but their immunopathogenic responses remain poorly understood. Materials and Methods Local immune responses were characterized in the liver, spleen, and central nervous system (CNS) of 50 naturally infected NTPs (31 Callithrix ...
Marina Pellegrino, Alessandra L. M. Santos, Cinthya dos Santos Cirqueira, Gabrielle F. P. da Silva Gagliotti, Ana Carolina Ewbank, Carlos Sacristán, Rodrigo Albergaria Ressio, Natália C. C. A. Fernandes, Juliana Mariotti Guerra, José Luiz Catão‐Dias   +9 more
wiley   +1 more source

Survey of Gastrointestinal Parasites of Farmed Pigs in Ghana

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Survey of Gastrointestinal Parasites of Farmed Pigs in Ghana Gastrointestinal parasites were common in pigs sampled from Kpone Katamanso Municipality, Ghana, with an overall prevalence of 67.6%. Complementary formol–ether concentration, modified McMaster, and modified Ziehl–Neelsen techniques improved parasite detection, while polymerase chain reaction
Antoinette V. Keleve, Sylvia Afriyie Squire, Doreen Dela Owusu‐Ntumy, Dennis Adusei, Linda Ama Owusuaa Amoah   +4 more
wiley   +1 more source

Effectiveness of Ginsenoside Rh2 Treatment in Mice Experimentally Infected With Cryptosporidium parvum

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
• This study evaluated the therapeutic effects of Ginsenoside Rh2 in mice experimentally infected with Cryptosporidium parvum and compared two dosing regimens. • Ginsenoside Rh2 reduced faecal oocyst shedding and improved body‐weight recovery in C. parvum‐infected mice.
Esengul Yildirim, Engin Balikci
wiley   +1 more source

Therapeutic Effects of Matricaria chamomilla Extract in an Immunosuppressed Mouse Model of Cryptosporidiosis

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Chamomile (Matricaria chamomilla) extract significantly reduced oocyst shedding and intestinal lesions in immunosuppressed mice infected with Cryptosporidium parvum, while enhancing antioxidant defences (GPx, TAC). These findings suggest chamomile as a promising phytotherapeutic agent for cryptosporidiosis. ABSTRACT Background Cryptosporidiosis, caused
Kousha Kiani, Mohammad Hashemnia, Farid Rezaei, Hadi Cheraghi   +3 more
wiley   +1 more source

An Overview of Peripheral Blood Mononuclear Cells as a Model for Immunological Research of Toxoplasma gondii and Other Apicomplexan Parasites

Frontiers in Cellular and Infection Microbiology, 2019
In biology, models are experimental systems meant to recreate aspects of diseases or human tissue with the goal of generating inferences and approximations that can contribute to the resolution of specific biological problems.
John Alejandro Acosta Davila, Alejandro Hernandez De Los Rios   +1 more
doaj   +1 more source

Prevalence, Genetic Diversity, and Zoonotic Transmission Potential of Cryptosporidium spp. in Snakes: A Systematic Review and Meta‐Analysis

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
This study provides the first global systematic synthesis of Cryptosporidium spp. infection in snakes. A pooled prevalence of 12.6% was identified, with higher occurrence in captive‐associated populations than in wild snakes. Eight Cryptosporidium species, including multiple zoonotic taxa, were reported, underscoring the potential role of snakes within
Ali Asghari, Ali Pouryousef, Kambiz Karimi, Amin Kheiri, Mohammad Reza Soltani, Farajolah Maleki   +5 more
wiley   +1 more source

Molecular Detection, Epidemiology and Genetic Diversity of Babesia microti Infecting Wild Rodents

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Blood samples from 284 rodents captured across seven districts of Pakistan were screened for Babesia microti using 18S rRNA PCR. Overall prevalence was 12%, with infection detected in Rattus rattus, Mus musculus and Rattus norvegicus. Phylogenetic analysis showed close similarity with global isolates.
Hafiza Misbah Munir, Muhammad Naeem, Maryam Ijaz, Shakir Ullah, Muhammad Usman, Zaki Ur Rehman Nasir, Adil Khan, Khalid S. Almaary, Amir Bouallegue, Atrsaw Asrat Mengistie, Furhan Iqbal   +10 more
wiley   +1 more source

Diversity of the Microbiomes in the Larval and Adult Stages of the European Cherry Fruit Fly (Rhagoletis cerasi) and Identification of Potential Biocontrol Candidate Taxa

Entomologia Experimentalis et Applicata, Volume 174, Issue 9, Page 999-1010, September 2026.
First comprehensive characterization of the R. cerasi microbiome is reported. Stage‐specific variations in microbial composition are documented. Multiple bacterial entomopathogen taxa are identified as potential biocontrol candidates for R. cerasi.
Mahdi N. Al‐Shammaa, Saber Delpasand Khabbazi, Remziye Nalcacioglu, Ismail Demir, Durdane Yanar, Zihni Demirbag   +5 more
wiley   +1 more source