Results 51 to 60 of about 27,596 (227)

Post‐LECA Origin and Diversification of an Axonemal Outer Arm Dynein Motor

Cytoskeleton, EarlyView.
ABSTRACT Dyneins were present in the last eukaryotic common ancestor (LECA) and play key roles in eukaryotic biology. Axonemal dyneins form the inner and outer arms that power ciliary beating, and it has long been recognized that outer arms in some organisms contain two different heavy chain motors, whereas those from other species contain a third unit
Stephen M. King
wiley   +1 more source

Studies on coccidian oocysts (Apicomplexa: Eucoccidiorida) [PDF]

Revista Brasileira de Parasitologia Veterinária, 2014
The oocysts of the coccidia are robust structures, frequently isolated from the feces or urine of their hosts, which provide resistance to mechanical damage and allow the parasites to survive and remain infective for prolonged periods. The diagnosis of coccidiosis, species description and systematics, are all dependent upon characterization of the ...
Berto, Bruno Pereira, McIntosh, Douglas, Lopes, Carlos Wilson Gomes   +2 more
openaire   +5 more sources

BCKDH: the missing link in apicomplexan mitochondrial metabolism is required for full virulence of Toxoplasma gondii and Plasmodium berghei [PDF]

, 2014
While the apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii are thought to primarily depend on glycolysis for ATP synthesis, recent studies have shown that they can fully catabolize glucose in a canonical TCA cycle.
Barrett, Michael P., Billker, Oliver, Creek, Darren J., Limenitakis, Julien, Macrae, James I., McConville, Malcolm J., Modrzynska, Katarzyna K., Oppenheim, Rebecca D., Pino, Paco, Polonais, Valerie, Seeber, Frank, Soldati-Favre, Dominique   +11 more
core   +1 more source

Discovery of an Atypical Arp2/3 Complex in Malaria Parasites Sheds New Light on Nuclear Actin

Cytoskeleton, EarlyView.
ABSTRACT The Arp2/3 complex is a key actin nucleator essential for cytoskeletal dynamics in eukaryotes. Previously believed absent in apicomplexan parasites, we recently identified an atypical Arp2/3 complex in malaria parasites consisting of five divergent subunits and a putative kinetochore‐associated factor.
Franziska Hentzschel, Friedrich Frischknecht, Matthias Marti   +2 more
wiley   +1 more source

Repurposing of conserved autophagy-related protein ATG8 in a divergent eukaryote

Communicative & Integrative Biology, 2016
Toxoplasma gondii and other apicomplexan parasites contain a peculiar non-photosynthetic plastid called the apicoplast, which is essential for their survival.
Maude F. Lévêque, Hoa Mai Nguyen, Sébastien Besteiro   +2 more
doaj   +1 more source

Sexual Development in Non-Human Parasitic Apicomplexa: Just Biology or Targets for Control?

Animals, 2021
The phylum Apicomplexa is a major group of protozoan parasites including gregarines, coccidia, haemogregarines, haemosporidia and piroplasms, with more than 6000 named species. Three of these subgroups, the coccidia, hemosporidia, and piroplasms, contain
Teresa Cruz-Bustos, Anna Sophia Feix, Bärbel Ruttkowski, Anja Joachim   +3 more
doaj   +1 more source

The genome of the protozoan parasite Cystoisospora suis and a reverse vaccinology approach to identify vaccine candidates [PDF]

, 2017
Vaccine development targeting protozoan parasites remains challenging, partly due to the complex interactions between these eukaryotes and the host immune system.
Aliaga-Leyton, Altenhoff, Anja Joachim, Aruna Shrestha, Bhopale, Blake, Blake, Blum, Bradford, Burset, Bärbel Ruttkowski, Cantarel, Claus Vogl, Conesa, Cui, Damer P. Blake, de Oliveira Lopes, Dlugonska, Elsheikha, Emanuelsson, Fiona Tomley, Flower, Gabner, Gajria, Gharahdaghi, Goodswen, Goodswen, Goodswen, Goodswen, Hassan, Hehl, Hiszczynska-Sawicka, Horton, Jackson, Jenkins, Jimenez, Joachim, Jones, Jongert, Kall, Kim, Kissinger, Korf, Kurtz, Larsen, Lillehoj, Lim, Lindsay, Loytynoja, Martens, Matrajt, McAllister, Meyer, Min, Monney, Monney, Mortazavi, Mundt, Myhre, Nam, Nicola Palmieri, Nishikawa, Ogedengbe, Parra, Petersen, Pizza, Ramaprasad, Reichel, Samarasinghe, Sato, Schulz, Schwarz, Schwarz, Shevchenko, Shrestha, Sonnhammer, Stanisic, Stanke, Stephen, Templeton, Thorvaldsdottir, Tomas Beck, Trapnell, Williams, Worliczek, Worliczek, Worliczek, Xiang, Zhu   +88 more
core   +2 more sources

Universal and Lineage‐Specific Patterns in the Distribution of ECOD Domain Homology Groups Across Superkingdoms

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Proteins are built from modular domains that serve as fundamental units of structure and evolution. While individual domains have been extensively cataloged, their collective distribution across the lineages of life has remained poorly resolved.
Rui Guo, Jimin Pei, Jing Zhang, Qian Cong, Nick V. Grishin, R. Dustin Schaeffer   +5 more
wiley   +1 more source

The Genus Hepatozoon (Apicomplexa: Adeleina) [PDF]

The Journal of Parasitology, 1996
Hemogregarines of the genus Hepatozoon are intraerythrocytic apicomplexan parasites that have been described from all groups of tetrapod vertebrates. Gametogenesis, fertilization, and sporogonic development, which culminates in the formation of polysporocystic oocysts, occur in the gut or hemocoel of a hematophagous arthropod definitive host. Merogonic
openaire   +2 more sources

Clinical, laboratory and epidemiological aspects of Cryptosporidium parvum and Cryptosporidium hominis infection: a integrative review [PDF]

Brazilian Journal of Biology
Cryptosporidium parvum and Cryptosporidium hominis infection causes cryptosporidiosis, which in humans can result in watery diarrhea that is usually self-limited in immunocompetent individuals, but can be chronic and fatal in immunocompromised ...
R. L. M. Mendonça, M. S. Miranda, A. C. Guimarães, A. P. Queiroga, H. F. M. Câmara, P. H. L. T. S. Anjos, J. V. Ferro, H. B. G. Messias, T. L. G. Q. Maranhão, A. C. S. Omena, A. C. Silva, C. J. Santos Júnior, B. C. Omena, M. G. S. Cavalcanti, T. J. M. Rocha, G. C. Ferreira Júnior   +15 more
doaj   +1 more source