Results 21 to 30 of about 614 (157)

Bee venom exhibits anti-cancer effects on tongue carcinoma cells by arresting cell cycle, inducing apoptosis, and suppressing cell migration [PDF]

Journal of Applied Oral Science
Objective Tongue squamous cell carcinoma (TSCC) is an aggressive oral cancer with notable treatment resistance. This in vitro study investigated anti-cancer effects of honey bee venom (BV)—a mixture of bioactive compounds—on the human TSCC cell line ...
Enas SABRY, Hagar M ZAYED, Ola M EZZATT, Iman FATHY, Hebatt-Allah S ELSAYEH, Nashwa EL-KHAZRAGY, Suzan SeifAllah IBRAHIM   +6 more
doaj   +2 more sources

Suppression of skin lesions and SLE nephritis by increasing Treg in MRL/FAS lpr mice by administration of bee venom Apitoxin®

Advances in Rheumatology
Background Apitoxin®, a drug based on bee venom was approved and released in Korea in 2003 as the ethical drug (ETC). It is well-known for its pain-relieving properties due to its potent anti-inflammatory effects.
Duk-Yeon Cho, Young-Mo Kang, SangHo Seol
doaj   +3 more sources

Sustainable Pest Management Using Biodegradable Apitoxin-Loaded Calcium-Alginate Microspheres [PDF]

Sustainability, 2021
Alternatives and replacements for synthetic chemical-based plant protectants are required. In this study biopolymeric microspheres containing arthropod-derived apitoxin are explored as a possible novel environmentally friendly formulation for plant protection.
Darija Lemic, Matej Orešković, Katarina M. Mikac, Marijan Marijan, Slaven Jurić, Kristina Vlahoviček-Kahlina, Marko Vinceković   +6 more
openaire   +3 more sources

Ultrasound wave transports apitoxin in arthritic joint. - Experimental study

Research, Society and Development, 2022
Man, in his common lore started using the toxin produced by bees, apitoxin, as a topical medication for rheumatoid arthritis in time immemorial. Systematically subjecting themselves to bee stings. In this study, we sought to use this substance, apitoxin, in an experimental model of induced arthritis.
Felipe Misael da Silva Morsoleto, Pedro Rondon Werneck, Fernando Russo Costa do Bomfim, Maria Jose Misael da Silva Morsoleto   +3 more
openaire   +1 more source

Anaphylactic shock with pulmonary eosinophilic infiltration due to honeybee attack in a donkey: case report

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2021
A case of a donkey attacked by Africanized honeybee is reported here with clinical signs of agitation, dehydration, congestion of the ocular mucous membranes, tongue edema, tachycardia and inspiratory dyspnea, and progression to death.
E. Zache, J.F. Cajueiro, A.Q. Andrade Neto, L. Almeida, R.R. Colares, J.A.B. Afonso, M.I. Souza, A. Arenales   +7 more
doaj   +1 more source

Cancer therapeutics inspired by defense mechanisms in the animal kingdom

Evolutionary Applications, Volume 13, Issue 7, Page 1681-1700, August 2020., 2020
Abstract Many animals have evolved toxins to defend themselves from predators and hunt prey. These toxins have been honed over millions of years by the unique selective pressures on each organism leading to a vast array of potent bioactive compounds, many of which have therapeutic potential.
Kathleen Noble, Aarushi Rohaj, Lisa M. Abegglen, Joshua D. Schiffman   +3 more
wiley   +1 more source

Comparative Determination of Melittin by Capillary Electrophoretic Methods

Journal of the Turkish Chemical Society, Section A: Chemistry, 2021
Bee venom from honey bees (Apis Mellifera L.) is known to have many pharmacological and biological properties. Melittin, a peptide consisting of 26 amino acids, is known as the main component of bee venom.
Melda AKAY , Zeynep KALAYCIOĞLU, Sevgi KOLAYLI, Bedia BERKER   +3 more
doaj   +1 more source

An overview of the bioactive compounds, therapeutic properties and toxic effects of apitoxin [PDF]

Food and Chemical Toxicology, 2019
Apitoxin, also known as bee venom (BV), is produced in two specialized abdominal glands of worker bees and is used as a defence weapon of bees’ colony (Choi et al., 2015; Zhang et al., 2016). In addition, this natural product has been used since the ancient times to relieve pain and to treat chronic inflammatory diseases such as rheumatoid arthritis ...
Pascoal, Ananias, Estevinho, Maria Manuela, Choupina, Altino, Sousa-Pimenta, Mário, Estevinho, Leticia M.   +4 more
openaire   +3 more sources

Bee stings: Report of a Fatal Case in an Adolescent

Iatreia, 2023
We report the case of a 16-year-old male adolescent weighing 60 kg who experienced massive bee sting intoxication, resulting in shock and generalized edema. Bee stings were distributed across his entire body. Documented rhabdomyolysis manifested with the
José Santiago Cortés-Guzmán, Adriana Zamora, Juan D. Domínguez   +2 more
doaj   +1 more source

Determination of protein binding affinities within hydrogel-based molecularly imprinted polymers (HydroMIPs) [PDF]

, 2014
Hydrogel-based molecularly imprinted polymers (HydroMIPs) were prepared for several proteins (haemoglobin, myoglobin and catalase) using a family of acrylamide-based monomers.
Alexander, Byrne, Byrne, Daniel M. Hawkins, Derek Stevenson, El-Sharif, Fernández-Barbero, Freitag, Gai, Hansen, Hawkins, Hazim F. EL-Sharif, Hilt, Hoshino, Hoshino, Kienberger, Kryscio, Lavignac, Lieberzeit, Mosbach, Piletsky, Poma, Reddy, Reddy, Stevenson, Subrayal M. Reddy, Vaidya   +26 more
core   +2 more sources