Results 101 to 110 of about 21,523 (174)

Liver disease in management and outcomes of European and Asian patients with atrial fibrillation: A report from two observational prospective registries

European Journal of Clinical Investigation, Volume 56, Issue 4, April 2026.
In this large European–Asian cohort of patients with atrial fibrillation, liver disease was linked to lower oral anticoagulant use—particularly in Europe—and to higher risks of mortality and cardiovascular events. These findings highlight the adverse impact of liver disease, especially when oral anticoagulation is withheld.
Davide Antonio Mei, Tommaso Bucci, Giulio Francesco Romiti, Bernadette Corica, Alena Shantsila, Hung‐Fat Tse, Giuseppe Boriani, Tze‐Fan Chao, Marco Proietti, Gregory Y. H. Lip   +9 more
wiley   +1 more source

Safety of anticoagulation with apixaban following acute traumatic brain injury: A case series

World Neurosurgery: X
Background: The rise in traumatic brain injuries (TBI) among geriatric patients, often using direct oral anticoagulants (DOACs), underscores the urgency to explore safe resumption of these medications post-injury.
Abhishek R. Mogili, Rodnell Busigó-Torres, Pemla Jagtiani, Bashar Zaidat, Jueria Rahman, Thomas Fetherston, Salazar A. Jones, Laura Salgado-Lopez, Zachary L. Hickman   +8 more
doaj   +1 more source

Estrategias de marketing para el lanzamiento y posicionamiento de Apixabán como el mejor anticoagulante oral en pacientes con fibrilación auricular [PDF]

, 2013
La industria farmacéutica enfrenta grandes retos al momento de investigar y desarrollar medicinas que cubran las necesidades ya sea de curar o aliviar a los pacientes, pero logrando que estos fármacos ocasionen los mínimos efectos secundario o efectos ...
Avilés Salguero, Lourdes de las Mercedes
core  

Measuring Direct Oral Anticoagulant (DOAC) Levels: Applications, Limitations, and Future Directions

International Journal of Laboratory Hematology, Volume 48, Issue 2, Page 250-258, April 2026.
ABSTRACT Introduction There are important challenges with the measurement and interpretation of direct oral anticoagulant (DOAC) anticoagulant effect including a lack of therapeutic ranges, inaccuracy of routinely available coagulation assays, lack of established thresholds for clinically significant effect, and uncertainty about how to apply the ...
Siraj Mithoowani, Chee Wee Tan, Deborah M. Siegal   +2 more
wiley   +1 more source

Seguimiento clínico de los pacientes anticoagulados con ACODs en el sector III de Zaragoza. Datos de vida real [PDF]

, 2016
La aparición en los últimos años de los anticoagulantes orales de acción directa ha supuesto una revolución en el tratamiento de los pacientes con fibrilación auricular.
Forga Gracia, Mario, Gabín Sebastián, Olga   +1 more
core  

Transforming Treatment: The Impact of Bariatric Surgery on Oral Drug Absorption

Obesity Reviews, Volume 27, Issue 4, April 2026.
ABSTRACT Obesity represents a significant threat to global public health, with an estimated 16% of adults worldwide (2022) being classified as people with obesity, with a body mass index of 30 or more. Bariatric surgery is regarded as the most effective treatment option for people with obesity, with the three main types of bariatric surgery being ...
Danielle Wigg, Andrea Edginton, Matthew D. Jones, Nikoletta Fotaki   +3 more
wiley   +1 more source

Apixaban and clopidogrel in a fixed-dose combination: Formulation and in vitro evaluation

Saudi Pharmaceutical Journal
Fixed-dose combination (FDC) products represent a novel, safe, and cost-effective formulation. Combined use of anticoagulant and antiplatelet medications is common among comorbid cardiovascular patients.
Ni'meh Al-Shami, Hani Naseef, Feras Kanaze   +2 more
doaj   +1 more source

Risks of thrombosis and hemorrhage in concurrent use of anticoagulants and potential interacting prostate cancer agents

Cancer, Volume 132, Issue 6, 15 March 2026.
Abstract Background Pharmacokinetic studies suggest that specific prostate cancer therapies may alter the metabolism of direct oral anticoagulants (DOACs), leading to elevated risks of thrombosis or bleeding. Methods To assess the risk of thrombosis or bleeding, population‐based, retrospective, parallel analyses were conducted in Ontario and Alberta ...
Tzu‐Fei Wang, Anna Clarke, Mitchell Rath, Samantha Yoo, Deena Fremont, Cynthia Wu, Pietro Ravani, Dominick Bossé, Robert Talarico, Marc Carrier, Manish M. Sood   +10 more
wiley   +1 more source

Anticoagulación en la fibrilación auricular: ACOD frente a cumarínicos [PDF]

, 2019
La fibrilación auricular es la arritmia cardiaca más frecuente en la actualidad y la que ocasiona un mayor número de complicaciones como consecuencia del proceso de embolización.
Alarcón Sisamón, Sergio, Lanuza Giménez, Fco. Javier   +1 more
core  

The effect of apixaban on the pharmacokinetics of digoxin and atenolol in healthy subjects

Clinical Pharmacology: Advances and Applications, 2017
Charles Frost,1 Yan Song,1 Zhigang Yu,2 Jessie Wang,3 Lois S Lee,4 Alan Schuster,5 Allyson Pollack,1 Frank LaCreta1 1Exploratory Clinical and Translational Research, Bristol-Myers Squibb, Princeton, NJ, USA; 2Medical Sciences, Amgen Asia R&D Center ...
Frost C, Song Y, Yu Z, Wang J, Lee LS, Schuster A, Pollack A, LaCreta F   +7 more
doaj