Results 111 to 120 of about 38,480 (291)

Reversal of apixaban induced alterations in hemostasis by different coagulation factor concentrates: significance of studies in vitro with circulating human blood.

PLoS ONE, 2013
Apixaban is a new oral anticoagulant with a specific inhibitory action on FXa. No information is available on the reversal of the antihemostatic action of apixaban in experimental or clinical settings.
Gines Escolar, Victor Fernandez-Gallego, Eduardo Arellano-Rodrigo, Jaume Roquer, Joan Carles Reverter, Victoria Veronica Sanz, Patricia Molina, Irene Lopez-Vilchez, Maribel Diaz-Ricart, Ana Maria Galan   +9 more
doaj   +1 more source

Use of direct oral anticoagulants in patients with atrial fibrillation in Scotland : applying a coherent framework to drug utilisation studies [PDF]

, 2017
Purpose: To report the use of direct oral anticoagulants (DOAC) for stroke prevention in patients with atrial fibrillation (AF) in Scotland and advocate the standardisation of drug utilisation research methods.
Alvarez-Madrazo, Samantha, Bennie, Marion, Mueller, Tanja, Robertson, Charles   +3 more
core   +1 more source

Advances in cardiac devices and bioelectronics augmented with artificial intelligence

The Journal of Physiology, EarlyView.
Abstract figure legend Interfaces between the human heart, diagnostic bioelectronics, artificial intelligence, and clinical care. From left to right: Human heart and biosensor interface; representative waveforms of common diagnostic bioelectronic sensing modalities.
Charles Stark, Eric Rytkin, Andrei Alexandru Mircea, Igor R. Efimov   +3 more
wiley   +1 more source

Apixaban [PDF]

Reactions Weekly, 2021
  +6 more sources

The Risk of Colonoscopy‐related Bleeding in Patients With or Without Continued Treatment With an Antithrombotic Agent

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives We prospectively investigated the risk of colonoscopy‐related bleeding in relation to antithrombotic treatment. Methods This prospective, observational, single‐center cohort study (NCT02594813) enrolled consecutive patients who underwent colonoscopy, including the removal of colorectal polyps, regardless of the continuation of ...
Emi Nonaka, Ichitaro Horiuchi, Akira Horiuchi, Satoshi Ukai, Noriko Takahata, Kimihiko Oishi   +5 more
wiley   +1 more source

State of play and future direction with NOACs: An expert consensus. [PDF]

, 2018
Atrial fibrillation (AF) and venous thromboembolism (VTE) are cardiovascular conditions significant in contemporary practice. In both, the use of anticoagulation with vitamin K antagonists (VKAs) has been traditionally used to prevent adverse events ...
A.J. Camm, A.T. Cohen, Ageno, Agnelli, Alings, Ansell, Ansell, Apostolakis, Avgil-Tsadok, Beyer-Westendorf, Beyer-Westendorf, Beyer-Westendorf, Bohula, Bouillon, Brunner-Ziegler, Caldeira, Caldeira, Camm, Cannon, Cohen, Cohen, Coleman, Connolly, Connolly, Connolly, Cronin-Fenton, De Caterina, De Caterina, De Caterina, De Caterina, Diener, Diener, Diener, Douketis, Easton, Eikelboom, Ensor, F. Verheugt, Fang, Fauchier, Forslund, Fox, Friberg, Friberg, Furugohri, G. Agnelli, G.Y. Lip, Gage, Gibson, Giugliano, Glund, Granger, Gross, Guo, H. Heidbuchel, Hankey, Heidbuchel, Heidbuchel, Heit, Heit, Hijazi, Hohnloser, Husted, Investigators, J.L. Zamorano, Kearon, Keeling, Khorana, Kirchhof, Kooiman, Kooistra, Larsen, Levy, Lip, Lip, Lip, Lip, Lip, Lublóy, Martinez, Masjuan, Mendell, Mendell, Miyasaka, Moore, Morgan, Mungall, Murphy, Márquez-Contreras, Nielsen, Oldgren, Paciaroni, Paciaroni, Patel, Perzborn, Peterson, Pinto, Pollack, Pollack, Price, Prins, Proietti, Proietti, R. De Caterina, Raskob, Renda, Roffi, Roldán, Ruff, Ruff, Sandén, Sardar, Sardar, Sarich, Schulman, Schulman, Senoo, Senoo, Shekelle, Sjögren, Song, Stacy, Stampfuss, Stangier, Steinberg, Tafur, The EINSTEIN investigators, The EINSTEIN–PE Investigators, van der Hulle, van Walraven, Verhamme, Vrijens, Watanabe, Weitz, Wolf, Zamorano   +135 more
core   +4 more sources

Impact of Direct Oral Anticoagulant Uptake on Hospitalizations for Stroke/Transient Ischemic Attack, Intracranial Hemorrhage, and Gastrointestinal Bleeding in Individuals With Atrial Fibrillation: A Population‐Based Study

Fundamental &Clinical Pharmacology, Volume 39, Issue 6, December 2025.
ABSTRACT Background Direct‐acting oral anticoagulants (DOACs) have largely replaced warfarin for stroke prevention in patients with atrial fibrillation, yet their population‐level impact on health outcomes and costs remains unclear. We examined whether the widespread uptake of DOACs was associated with changes in hospitalization rates and costs for ...
Tony Antoniou, Daniel McCormack, Tianru Wang, Mina Tadrous, Tara Gomes   +4 more
wiley   +1 more source

Trends in drug–drug interaction prevalence and longitudinal associations with health outcomes in the older community‐dwelling population: Findings from The Irish LongituDinal study on Ageing

British Journal of Clinical Pharmacology, Volume 91, Issue 11, Page 3244-3256, November 2025.
Aims We estimate trends in severe drug–drug interaction (DDI) prevalence and examine longitudinal associations between DDI exposure and health outcomes (emergency department [ED] visits, quality‐of‐life [QoL] and functional decline) over approximately 10‐years in the older community‐dwelling population in Ireland.
John E. Hughes, Caitriona Cahir, Kathleen E. Bennett   +2 more
wiley   +1 more source

The effect of apixaban on the pharmacokinetics of digoxin and atenolol in healthy subjects

Clinical Pharmacology: Advances and Applications, 2017
Charles Frost,1 Yan Song,1 Zhigang Yu,2 Jessie Wang,3 Lois S Lee,4 Alan Schuster,5 Allyson Pollack,1 Frank LaCreta1 1Exploratory Clinical and Translational Research, Bristol-Myers Squibb, Princeton, NJ, USA; 2Medical Sciences, Amgen Asia R&D Center ...
Frost C, Song Y, Yu Z, Wang J, Lee LS, Schuster A, Pollack A, LaCreta F   +7 more
doaj  

Association Between Statins Use and Major Bleeding in Patients Using Direct Oral Anticoagulants for Atrial Fibrillation

Pharmacoepidemiology and Drug Safety, Volume 34, Issue 11, November 2025.
ABSTRACT Background Direct oral anticoagulants (DOAC) were developed as an alternative to vitamin K antagonists in the treatment of NVAF. Statins are frequently prescribed drugs for the prevention of atherosclerotic cardiovascular disease. A potential interaction between DOACs and statins has been described, suggesting that their concomitant use may ...
A. de Burgos‐González, L. Cea‐Soriano, C. Huerta‐Álvarez   +2 more
wiley   +1 more source