Safety of anticoagulation with apixaban following acute traumatic brain injury: A case series
Background: The rise in traumatic brain injuries (TBI) among geriatric patients, often using direct oral anticoagulants (DOACs), underscores the urgency to explore safe resumption of these medications post-injury.
Abhishek R. Mogili +8 more
doaj +1 more source
Use of andexanet alfa: A British Society for Haematology position statement
British Journal of Haematology, EarlyView.
Richard J. Buka +10 more
wiley +1 more source
Managing patients taking novel oral anticoagulants (NOAs) in dentistry: A discussion paper on clinical implications [PDF]
Background The aim of this paper is to contribute to the discussion on how to approach patients taking new orally administered anticoagulants (NOAs) dabigatran etexilate (a direct thrombin inhibitor), rivaroxaban and apixaban (factor Xa inhibitors ...
Costantinides, Fulvia +3 more
core +1 more source
Epidemiology of Cancer‐Associated Venous Thromboembolism Across the United States
ABSTRACT Prior epidemiological studies on cancer‐associated venous thromboembolism (VTE) were limited by homogenous patient populations. We leverage Cosmos, a collaborative dataset of Epic electronic health record systems, to conduct an updated evaluation of cancer‐associated VTE in the United States (US).
Barbara D. Lam +7 more
wiley +1 more source
Cost-effectiveness analysis of left atrial appendage occlusion compared with pharmacological strategies for stroke prevention in atrial fibrillation [PDF]
Background Transcatheter left atrial appendage occlusion (LAAO) is a promising therapy for stroke prophylaxis in non-valvular atrial fibrillation (NVAF) but its cost-effectiveness remains understudied. This study evaluated the cost- effectiveness of LAAO
Chow, Ines Hang-Iao +6 more
core +1 more source
Acute Systemic Complications Following High‐Dose Semaglutide Reinitiation in an Elderly Patient
ABSTRACT Severe gastrointestinal intolerance with systemic complications can occur within hours of reinitiating high‐dose semaglutide after a prolonged treatment interruption, even in patients who previously tolerated the medication. Elderly patients with comorbidities may be particularly vulnerable.
Jay Mehta, Brent Tai, Johnathan Frunzi
wiley +1 more source
Apixaban and clopidogrel in a fixed-dose combination: Formulation and in vitro evaluation
Fixed-dose combination (FDC) products represent a novel, safe, and cost-effective formulation. Combined use of anticoagulant and antiplatelet medications is common among comorbid cardiovascular patients.
Ni'meh Al-Shami +2 more
doaj +1 more source
Flecainide‐Induced Interstitial Lung Disease: A Case Report and Review of the Literature
ABSTRACT This case describes a rare adverse effect in which the subject developed interstitial lung disease after initiating a class IC antiarrhythmic, flecainide. There is no current treatment recommendation for flecainide‐induced interstitial lung disease.
Elizabeth Jenkins +2 more
wiley +1 more source
The effect of apixaban on the pharmacokinetics of digoxin and atenolol in healthy subjects
Charles Frost,1 Yan Song,1 Zhigang Yu,2 Jessie Wang,3 Lois S Lee,4 Alan Schuster,5 Allyson Pollack,1 Frank LaCreta1 1Exploratory Clinical and Translational Research, Bristol-Myers Squibb, Princeton, NJ, USA; 2Medical Sciences, Amgen Asia R&D Center ...
Frost C +7 more
doaj
Thromboprophylaxis With Apixaban in Patients Undergoing Major Orthopedic Surgery: Meta-Analysis and Trial-Sequential Analysis [PDF]
Background: Venous thromboembolism (VTE) is a potentially fatal complication of orthopedic surgery, and until recently, few antithrombotic compounds were available for postoperative thromboprophylaxis.
Caldeira, D +4 more
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