Results 51 to 60 of about 29,392 (188)

Efficacy and safety of apixaban and warfarin in prevention of ischemic stroke: a systematic review and meta-analysis

open access: yes, 2022
Introduction Due to various limitations of warfarin use, non-vitamin K oral anticoagulants have gradually become the first choice for the prevention of ischemic stroke. This article will comprehensively and systematically evaluate the efficacy and safety
Wei Xie   +6 more
core   +1 more source

Pulmonary Embolism—A Century of Progress

open access: yesANZ Journal of Surgery, EarlyView.
Reviews a century of progress in the diagnosis, prevention, and management of pulmonary embolism; from the first successful surgical embolectomy in 1924 to advanced imaging, pharmacological thromboprophylaxis, and treatment. In the 21st century, advances include catheter‐directed thrombolysis or mechanical thrombectomy under decision‐making guidance of
D. A. Watters
wiley   +1 more source

Beyond Anticoagulant Exposure: Determinants of Mortality After Gastrointestinal Bleeding Across DOAC, Warfarin and Non‐Anticoagulated Patients

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Among 11,387 patients with acute gastrointestinal bleeding, overlap‐weighted analyses (n = 10,044) found no statistically significant association between direct oral anticoagulant or warfarin use and 30‐day or 1‐year mortality. Haemodynamic shock was associated with 30‐day mortality, whereas age and Internal Medicine ward admission were associated with
Esther Forkosh   +5 more
wiley   +1 more source

Single- and multiple-dose pharmacokinetics, pharmacodynamics, and safety of apixaban in healthy Chinese subjects

open access: yesClinical Pharmacology: Advances and Applications, 2013
Yimin Cui,1 Yan Song,2 Jessie Wang,2 Zhigang Yu,2 Alan Schuster,2 Yu Chen Barrett,2 Charles Frost2 1Peking University First Hospital, Beijing, People's Republic of China; 2Bristol-Myers Squibb, Princeton, NJ, USA Background: The pharmacokinetics (PK),
Cui Y   +6 more
doaj  

Apixaban linearity profile for hydrotropic solubilization

open access: yesBLDE University Journal of Health Sciences, 2020
A study on the hydrotropic solubility and linearity profile of Apixaban was carried out by using Sodium Salicylate as the solubilizing agent as Apixaban is poorly soluble in water.
Santosh Karajgi, Shripad Potadar
doaj   +1 more source

Bruton tyrosine kinase inhibitors and cardiovascular adverse events

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Bruton tyrosine kinase inhibitors (BTKi) have transformed the management of chronic lymphocytic leukaemia and other B‐cell malignancies, yet their therapeutic benefit is tempered by clinically relevant cardiovascular toxicities (predominantly atrial fibrillation, hypertension, bleeding and ventricular arrhythmias).
Massimiliano Camilli   +4 more
wiley   +1 more source

Sustained resolution of anticoagulation related iron deficiency anemia with the use of apixaban

open access: yes, 2019
Successful resolution of iron deficiency anemia in the context of anticoagulation with rivaroxaban was seen when apixaban is used alternatively.
Alghamry, Alaa   +8 more
core   +1 more source

Do We Really Know How to Manage Anticoagulated Patients for Periodontal Nonsurgical Therapy? An Observational Cohort Study

open access: yesInternational Journal of Dental Hygiene, EarlyView.
ABSTRACT Objectives The aim of this work is to assess and compare the impact of direct oral anticoagulants (DOACs) versus vitamin K antagonists (VKA) during and immediately after periodontal nonsurgical therapy. Materials and Methods A prospective observational cohort study was conducted with patients who presented a history of cardiovascular disease ...
F. Berton   +5 more
wiley   +1 more source

Apixaban in bridge to transplant and destination LVAD - rationale and study design: the ApixiVAD trial. [PDF]

open access: yes
AIMS Use of novel anticoagulation in mechanical circulatory support is controversial. We report the rationale and design of the ApixiVad pilot trial, a pilot study testing the safety of apixaban as an anticoagulant in patients bridged to transplant ...
Ricardo Deveza   +5 more
core   +2 more sources

Refining Residual Ischemic Stroke Risk in Anticoagulated Atrial Fibrillation Using Index Outpatient LA Diameter: The CHA2DS2‐VALa Score

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
In anticoagulated atrial fibrillation, residual ischemic stroke risk persists despite guideline‐directed therapy. In this single‐center cohort, an enlarged index outpatient left atrial diameter independently predicted stroke and improved risk stratification when added to CHA2DS2‐VA (CHA2DS2‐VALa), supporting a simple, clinically implementable ...
Sefa Erdi Ömür   +7 more
wiley   +1 more source

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