Results 101 to 110 of about 168,851 (224)

Human parvovirus infection and aplastic crisis in hereditary spherocytosis

Current Medicine Research and Practice, 2011
Parvovirus B19 is usually associated with an acute, self-limiting disease. In patients with congenital haemolytic anaemia, infection with this virus can cause an aplastic crisis.
A Gogia, A Kakar, S P Byotra, U Parakh, M Bhargava   +4 more
doaj  

Functional validation of a modified platelet desialylation test for immune and hereditary thrombocytopenias

Transfusion Medicine, EarlyView.
Abstract Background Thrombocytopenia arises from heterogeneous inherited and acquired disorders, and identifying the underlying platelet clearance mechanisms remains challenging. Platelet desialylation, characterised by loss of sialic acid and consequent exposure of terminal β‐galactose residues recognised by the Ashwell–Morell receptor, represents an ...
Karen Nogueira Chinoca Ziza, Thamy Caroline Silva, Mateus Domentino, Marina Cavalcanti Albuquerque Veiga Conrado, João Vitor Bernardo Oliveira, Felipe Augusto Rós, Caroline Gabe, Elyse Moritz, Akemi Chiba, Paula Villaça, Vanderson Rocha, Alfredo Mendrone‐Junior, José Bordin, Dante Langhi, Carla Luana Dinardo   +14 more
wiley   +1 more source

Successful pregnancy following aplastic anaemia.

, 1995
Pregnancy following idiopathic aplastic anaemia is rare and is difficult to manage because of life-threatening episodes of bleeding and infections. Only a handful of cases has been reported in the literature.
Bosco, J.J., Lim, J., Leong, K.W., Teh, A.   +3 more
core  

Dissecting the genomic traits and clinical course of secondary myelodysplastic syndrome following aplastic anaemia: A milestone

Dissecting the genomic traits and clinical course of secondary myelodysplastic syndrome following aplastic anaemia is a milestone. The report by Li and colleagues investigates determinants of evolution to myelodysplastic syndrome and acute myeloid ...
Gurnari C., Visconte V.
core   +1 more source

Cyclophosphamide conditioning in patients with severe aplastic anaemia given unrelated marrow transplantation: a phase 1–2 dose de-escalation study

The Lancet Haematology, 2015
Summary Background The optimum preparative regimen for unrelated donor marrow transplantation in patients with severe aplastic anaemia remains to be established.
P. Anderlini, Juan Wu, I. Gersten, M. Ewell, J. Tolar, J. Antin, R. Adams, S. Arai, G. Eames, M. Horwitz, J. McCarty, R. Nakamura, M. Pulsipher, S. Rowley, E. Leifer, S. Carter, N. Difronzo, M. Horowitz, D. Confer, H. Deeg, M. Eapen   +20 more
semanticscholar   +1 more source

Performance evaluation of a CD34 expression assay by digital PCR in bone marrow harvest from healthy donors

Transfusion, EarlyView.
Abstract Background The aim of this study was to investigate a CD34 expression assay as an additional tool for the total nucleated cell (TNC) count assessment in bone marrow harvest (BMH) obtained from healthy donors. Study Design and Methods Samples obtained from bone marrow donors (n = 71) were analyzed for CD34 expression using a digital PCR assay ...
Miguel Waterhouse, Anja Kaufmann, Martina David, Sabine Enger, Melanie Sieder, Darina Siegmund, Milena Pantic, Justyna Rawluk, Robert Zeiser, Claudia Wehr, Ralph Wäsch, Justus Duyster, Jürgen Finke, Chrissoula Kiote‐Schmidt   +13 more
wiley   +1 more source

Outcome of allogenic bone marrow transplantation in aplastic Anaemia

Journal of the Pakistan Medical Association
Objective: To evaluate early outcomes of allogeneic bone marrow transplantation in patients with aplastic anaemia. Method: The retrospective, observational study was conducted at the Department of Clinical Haematology and Bone Marrow Transplantation ...
Shehzad Sarwar, Uzair Ahmed, Hafiz Muhammad Nadeem, Asghar Ali, Muhammad Farhan, Muhammad Afzal   +5 more
doaj   +1 more source

Clinicopathological Analysis of Pancytopenia - A Tertiary Care Centre Study

JK Science, 2022
Background: Pancytopenia is itself not a disease; it however is the combination of presence of anaemia, leucopenia and thrombocytopenia due to a variety of underlying disorders.
Bharti Devi Thaker, Anu Gupta, Rashmi Aithmia   +2 more
doaj  

Aplastic crisis due to human parvovirus B19 infection in hereditary hemolytic anaemia Crise aplástica devido à infecção por parvovirus humano B19 em anemia hemolítica hereditária

Revista do Instituto de Medicina Tropical de São Paulo, 1992
Specific anti-B19 IgM was demonstrated in sera from three children showing transient aplastic crisis. A two years-old boy living in Rio de Janeiro suffering from sickle-cell anaemia showed the crisis during August, 1990.
R. C. N. Cubel, M. C. Valadão, W. V. Pereira, M. C. Magalhães, J. P. Nascimento   +4 more
doaj   +1 more source

The lymphocyte function of allogeneic peripheral blood stem cell grafts is associated with relapse and cytomegalovirus reactivation

Transfusion, EarlyView.
Abstract Background Allogeneic hematopoietic stem cell transplantation (HSCT) is a treatment primarily for hematological malignancies. Infections, relapse, and graft versus host disease (GvHD) are some of the most common adverse events following HSCT. We aimed to evaluate whether the lymphocyte function of the stem cell graft was associated with these ...
Anna Söderström, Tengyu Wang, Johan Törlén, Hannes Lindahl, Davide Valentini, Stephan Mielke, Klara Asplund Högelin, Rebecca Axelsson Robertson, Michael Uhlin   +8 more
wiley   +1 more source