Results 111 to 120 of about 168,851 (224)

Diagnostic and management dilemma of a pancreas-kidney transplant recipient with aplastic anaemia

open access: yes, 2014
We report a case of a 57-year-old woman with type I diabetes who had received a simultaneous pancreas-kidney (SPK) transplant maintained on tacrolimus, mycophenolic acid (MPA) and prednisolone.
Lim, Wai Hon   +3 more
core   +1 more source

Chromosome anomalies in bone marrow as primary cause of aplastic or hypoplastic conditions and peripheral cytopenia: disorders due to secondary impairment of RUNX1 and MPL genes

open access: yesMolecular Cytogenetics, 2012
Background Chromosome changes in the bone marrow (BM) of patients with persistent cytopenia are often considered diagnostic for a myelodysplastic syndrome (MDS).
Marletta Cristina   +15 more
doaj   +1 more source

Breakthrough Hemolysis in Paroxysmal Nocturnal Hemoglobinuria: Mechanistic Insights and Management Strategies

open access: yesTransfusion, EarlyView.
Abstract Background Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal hematopoietic stem cell disorder caused by somatic mutations in the PIGA gene, resulting in loss of glycosylphosphatidylinositol (GPI)‐anchored proteins, including the complement regulatory proteins, CD55 and CD59.
Ganesh Raman   +4 more
wiley   +1 more source

Genotyping of human parvovirus B19 in clinical samples from Brazil and Paraguay using heteroduplex mobility assay, single-stranded conformation polymorphism and nucleotide sequencing

open access: yesMemorias do Instituto Oswaldo Cruz, 2011
Heteroduplex mobility assay, single-stranded conformation polymorphism and nucleotide sequencing were utilised to genotype human parvovirus B19 samples from Brazil and Paraguay.
Marcos César Lima de Mendonça   +8 more
doaj   +1 more source

Passive acquisition of hepatitis B virus antibodies after allogeneic hematopoietic cell transplantation

open access: yesTransfusion, EarlyView.
Abstract Background Newly positive hepatitis B virus (HBV) serologic results after allogeneic hematopoietic cell transplantation (HCT) may reflect passive antibody transfer from blood‐derived products rather than HBV infection. We investigated the incidence and temporal patterns of hepatitis B surface antibody (anti‐HBs) and antibody to hepatitis B ...
Takaaki Konuma   +7 more
wiley   +1 more source

Impact of nationwide parvovirus B19 DNA screening and identification of transfusion‐transmitted infections

open access: yesVox Sanguinis, EarlyView.
Abstract Background and Objectives Parvovirus B19 (B19V) testing is often not required to release blood components. However, the European Pharmacopoeia requires that plasma pools for fractionation contain no more than 104 IU/mL of B19V DNA. In France, pool B19 nucleic acid testing (NAT) screening was performed by Établissement Français du Sang since ...
Virginie de la Taille   +12 more
wiley   +1 more source

Clinical Laboratory Innovations: Nanoscale Detection of Chloramphenicol Using Nanomaterial Biosensors

open access: yesAnalytical Science Advances, Volume 7, Issue 2, December 2026.
Nanosensor schematic functionalized with specific bioreceptors that produce electrochemical signals upon Chloramphenicol binding. Resulting voltammetric readouts (differential pulse, square‐wave, and cyclic voltammetry) are analyzed to identify and quantify Chloramphenicol.
Nava Moghadasian Niaki   +5 more
wiley   +1 more source

Low dose cyclosporine-a therapy in severe aplastic anaemia

open access: yes, 2001
Objective : The present study was conducted to evaluate the efficacy of low dose cyclosporine-A in the patients of severe aplastic anaemia, who cannot afford allogenic bone marrow transplantation and immunosuppressive therapy with antithymocyte globulin ...
Jha, V. C.   +4 more
core  

SLE Complicated With AIHA and Parvovirus B19 Infection Secondary to PRCA: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 11, November 2026.
We report the diagnosis and treatment process of a female with SLE and AIHA infected with parvovirus B19 and secondary PRCA. Interestingly, there was no significant increase in hemoglobin after IVIG treatment for more than 50 days; however, the addition of foscarnet showed good efficacy.
Mingquan Xing   +4 more
wiley   +1 more source

Pattern of Non-malignant Haematological Disease Events among OPD Attendees in a Tertiary Care Hospital

open access: yesHaematology Journal of Bangladesh
Background: Non-malignant haematological disorders, including anaemias, haemophilias, different bleeding, and coagulation disorders are prevalent in outpatient settings and often present significant clinical challenges.
Maruf Al Hasan   +7 more
doaj   +1 more source

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