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Acquired severe aplastic anaemia: how medical therapy evolved in the 20th and 21st centuries
The progress in aplastic anaemia (AA) management is one of success. Once an obscure entity resulting in death in most affected can now be successfully treated with either haematopoietic stem cell transplantation (HSCT) or immunosuppressive therapy (IST).
P. Scheinberg
semanticscholar +1 more source
A case of severe aplastic anaemia after SARS‐CoV‐2 vaccination
There is increasing awareness about the possible relationship between severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) vaccines and the development of haematological diseases, including autoimmune cytopenias (AICs) and complement-mediated ...
N. Cecchi +3 more
semanticscholar +1 more source
COVID-19 infection in patients with severe aplastic anaemia
The coronavirus disease 2019 (COVID-19) pandemic has caused concern among physicians caring for immunosuppressed patients. Aplastic anaemia (AA) is a rare life-threatening bone marrow failure disorder that presents with severe pancytopenia and a ...
C. Paton +6 more
semanticscholar +1 more source
REVESZ SYNDROME AND DIFFERENTIAL DIAGNOSIS OF PANCYTOPENIA AND APLASTIC ANEMIA – CASE REPORT
We are presenting a case of a boy with Revesz syndrome, and through an example of his diagnostic pathway, we are presenting a differential diagnosis of pancytopenia and aplastic anaemia. Revesz syndrome is a rare and severe form of dyskeratosis congenita,
Matjaž Homšak +4 more
doaj +1 more source
Objectives: Severe aplastic anemia is characterized by a hypocellular bone marrow and peripheral cytopenia. Mesenchymal stem cells (MSCs) play a crucial role in haematopoietic stem cells (HSCs) development and the development of microenvironment suitable
Sarmistha Adhikari +3 more
doaj +1 more source
Parvovirus Infection Causing Aplastic Anaemia in an Immunocompetent Patient Diagnosed by Bone Marrow Aspiration Cytology [PDF]
Human Parvovirus infection is associated with transient aplastic crisis as a most common complication in chronic haemolytic anaemia patients. Very few case reports are available regarding aplastic crisis in immunocompetent patients. Here the authors are
Ranjana Giri, Urmila Senapati
doaj +1 more source
Aplastic anaemia treated using eltrombopag in a dog
2023 Acuerdos transformativos CRUEA 2-year-old, neutered, female beagle was presented to a referral hospital for investigation of pancytopenia. The patient had a history of recurrent infections and, on previous blood tests, anaemia, leukopenia and ...
Atencia Fernández, Sabela María +3 more
core +1 more source
A previous dose‐finding study has suggested that romiplostim is effective in patients with refractory aplastic anaemia (AA) and 10 µg/kg once weekly was recommended as a starting dose.
J. Jang +21 more
semanticscholar +1 more source
Distinctive and common features of moderate aplastic anaemia
The therapy algorithm for severe aplastic anaemia (sAA) is established but moderate AA (mAA), which likely reflects a more diverse pathogenic mechanism, often represents a treatment/management conundrum.
B. Patel +14 more
semanticscholar +1 more source
APLASTIC ANAEMIA – THERAPEUTIC AND DEONTOLOGICAL ASPECTS [PDF]
Aplastic Anaemia is a severe potentially fatal haematological syndrome, characterised by peripheral pancytopenia and bone marrow hypoplasia, with an occurrence rate of 2-6 cases per million per year.
Andreea Ligia Dinca +4 more
doaj +1 more source

