Results 41 to 50 of about 168,851 (224)

Case report of aplastic anaemia detected in third trimester of pregnancy: dilemmas faced [PDF]

, 2020
Aplastic anaemia with pregnancy is rarely encountered. Management of aplastic anaemia in pregnancy primarily involves a multidisciplinary approach offering supportive care.
Udgire, Sunil Prabhakar, Kamath, Gayathri Dinesh, Katewa, Divya, Sunil Prabhakar Udgire, Divya Katewa, Gayathri Dinesh Kamath   +5 more
core   +1 more source

APLASTIC ANAEMIA IN CAPRINE FLUOROSIS [PDF]

Assiut Veterinary Medical Journal, 1984
The present work aimed to study the picture of anemia fllowing caprine fluorosis. The relation of such anemia to iron and copper levels was also discussed.
M.H. KARRAM, A.A. AMER, H.A. IBRAHIM
doaj   +1 more source

Advances in understanding the pathogenesis of acquired aplastic anaemia

British Journal of Haematology, 2018
This review examines the evidence that bone marrow failure (BMF) in aplastic anaemia (AA) is due to loss of haematopoietic stem cells (HSCs), which, in turn, is caused by deranged immunity and inflammation.
L. Luzzatto, A. Risitano
semanticscholar   +1 more source

Autoimmune cytopenias (AIC) following allogeneic haematopoietic stem cell transplant for acquired aplastic anaemia: a joint study of the Autoimmune Diseases and Severe Aplastic Anaemia Working Parties (ADWP/SAAWP) of the European Society for Blood and Marrow Transplantation (EBMT)

Bone Marrow Transplantation, 2019
This retrospective study explored the incidence of autoimmune cytopenia (AIC) in 530 paediatric and adult patients with acquired aplastic anaemia (aAA) who underwent first allogeneic HSCT between 2002 and 2012.
Paul D. E. Miller, J. Snowden, R. de Latour, S. Iacobelli, D. Eikema, C. Knol, Judith C. W. Marsh, C. Rice, M. Koh, F. Fagioli, S. Chaganti, J. Finke, Rafael F. Duarte, P. Bader, D. Farge, J. Passweg, J. Madrigal, C. Dufour   +17 more
semanticscholar   +1 more source

Revisiting acquired aplastic anaemia: current concepts in diagnosis and management

Internal medicine journal (Print), 2019
Acquired aplastic anaemia is a rare, serious, immunologically mediated bone marrow failure syndrome, characterised by marrow hypoplasia of varying severity and significant pancytopenia. Careful attention and investigation, including molecular testing, is
D. Clucas, L. Fox, E. Wood, F. S. Hong, J. Gibson, A. Bajel, J. Szer, P. Blombery, Z. McQuilten, D. Hiwase, F. Firkin, M. Cole-Sinclair   +11 more
semanticscholar   +1 more source

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga, Anne B. Verbeek, Caroline A. Lindemans, Emilie P. Buddingh   +3 more
wiley   +1 more source

HLA-lacking clones in aplastic anaemia: Adaptive or maladaptive? [PDF]

HLA loss represents the result of immune forces shaping bone marrow clonal dynamics in immune aplastic anaemia. Human leukocyte antigen (HLA)-deficient clones may rescue haematopoiesis by evading immune attacks, potentially guiding treatment strategies ...
Lima A. C. M., Pagliuca S., Gurnari C., Gurnari, Carmelo, Pagliuca, Simona, Lima, Alberto Cardoso Martins   +5 more
core   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Treatment of aplastic anaemia with granulocyte-colony stimulating factor and risk of malignancy. Italian Aplastic Anaemia Study Group

, 2001
Granulocyte-colony stimulating factor (G-CSF) is being increasingly used in healthy volunteers to harvest haemopoietic stem cells. A possible role of G-CSF in the development of clonal disorders or leukaemia has been suggested.
Bacigalupo, A, BACIGALUPO A., ARCESE, WILLIAM, LOCATELLI, FRANCO, Eros Di Bona, DI BONA E, Di Bona, E, ARCESE W, LOCASCIULLI A, Franco Locatelli, Anna Locasciulli, Arcese, W, Locatelli F., Di Bona E., Locasciulli, A, Locasciulli A., Arcese W., Andrea Bacigalupo, Locatelli, F, Bacigalupo, A., William Arcese   +20 more
core   +2 more sources

A mutation in a functional Sp1 binding site of the telomerase RNA gene (hTERC) promoter in a patient with Paroxysmal Nocturnal Haemoglobinuria [PDF]

, 2004
Background<br/><br/> Mutations in the gene coding for the RNA component of telomerase, hTERC, have been found in autosomal dominant dyskeratosis congenita (DC) and aplastic anemia.
Ulku, B., Bessler, M., Bilsland, A., Mason, Philip J, Vulliamy, T., Serakinci, Nedime, Dokal, I., Ar, C., Ar, C, Marrone, Anna, Dokal, Inderjeet, Ulku, B, Bessler, Monica, Erzik, C, Serakinci, N, Serakinci, N., Marrone, A, Zhao, Jiangqin, Zhao, J, Dokal, I, Bilsland, A, Mason, PJ, Bilsland, Alan, Ulku, Birsen, Keith, W.N., Bessler, M, Vulliamy, T, Vulliamy, Tom, Keith, W Nicol, Erzik, Can, Marrone, A., Erzik, C., Zhao, J., Mason, P.J., Ar, Cem, Keith, WN, Tom Vulliamy, Alan Bilsland, W Nicol Keith, Jiangqin Zhao, Monica Bessler, Anna Marrone, Inderjeet Dokal, Nedime Serakinci, Philip J Mason, Cem Ar, Can Erzik, Birsen Ulku, Mason, Philip J., Keith, W. Nicol, AR, Muhlis Cem   +50 more
core   +2 more sources