Results 41 to 50 of about 53,574 (237)

Case report of aplastic anaemia detected in third trimester of pregnancy: dilemmas faced [PDF]

, 2020
Aplastic anaemia with pregnancy is rarely encountered. Management of aplastic anaemia in pregnancy primarily involves a multidisciplinary approach offering supportive care.
Udgire, Sunil Prabhakar, Kamath, Gayathri Dinesh, Katewa, Divya   +2 more
core   +1 more source

HLA-lacking clones in aplastic anaemia: Adaptive or maladaptive? [PDF]

HLA loss represents the result of immune forces shaping bone marrow clonal dynamics in immune aplastic anaemia. Human leukocyte antigen (HLA)-deficient clones may rescue haematopoiesis by evading immune attacks, potentially guiding treatment strategies ...
Lima A. C. M., Pagliuca S., Gurnari C.
core   +1 more source

Treatment of aplastic anaemia with granulocyte-colony stimulating factor and risk of malignancy. Italian Aplastic Anaemia Study Group

, 2001
Granulocyte-colony stimulating factor (G-CSF) is being increasingly used in healthy volunteers to harvest haemopoietic stem cells. A possible role of G-CSF in the development of clonal disorders or leukaemia has been suggested.
Bacigalupo, A, BACIGALUPO A., ARCESE, WILLIAM, LOCATELLI, FRANCO, Eros Di Bona, DI BONA E, Di Bona, E, ARCESE W, LOCASCIULLI A, Franco Locatelli, Anna Locasciulli, Arcese, W, Locatelli F., Di Bona E., Locasciulli, A, Locasciulli A., Arcese W., Andrea Bacigalupo, Locatelli, F, Bacigalupo, A., William Arcese   +20 more
core   +2 more sources

Active Emergency Management of Adult Acute Epiglottitis: An Analysis of 570 Cases

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Acute epiglottitis, which is primarily caused by bacterial infection, can quickly progress to life‐threatening airway obstruction. The first 24 h after symptom onset is a critical window for management. However, few studies have evaluated the effect of emergency management during this period or have identified the factors that ...
Bo‐Jun Shen, Xu‐Lan Tang, Chun‐Yan Li, Yang‐Jun Liu, Hong‐Liang Yi, Shan‐Kai Yin, Kai‐Ming Su, Su‐Ru Liu   +7 more
wiley   +1 more source

Indigenous antithymocyte globulin-equine to treat aplastic anaemia in adults: a case series from two centres in northeast India

Hematology, Transfusion and Cell Therapy
Background: Immunosuppressive therapy is the standard management of adults with aplastic anaemia. Antithymocyte globulin is used as first-line treatment of patients not eligible for bone marrow transplantation.
Asif Iqbal, Abhijit Phukan, Chandana Sharma   +2 more
doaj   +1 more source

Allopurinol: Sorrow to the marrow

Journal of Family Medicine and Primary Care, 2020
Allopurinol is a xanthine oxidase inhibitor used in management of chronic gout. It acts by reducing the amount of uric acid by inhibiting purine metabolism.
U R Raaju, Siddharth Gosavi, K Sriharsha
doaj   +1 more source

Nomenclature on Immune‐Mediated Drug Reactions: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Over the past several decades, there have been significant advances in our understanding of both immunological and pharmacological mechanisms of adverse drug reactions (ADRs). Immune‐mediated drug reactions (IMDRs) represent a small proportion of ADRs and are caused by a pathological activation of the immune system or inflammatory pathways ...
Maria J. Torres, Cristobalina Mayorga, Elizabeth J. Phillips, Adriana Ariza, Annick Barbaud, Patrizia Bonadonna, Mariana Castells, Gülfem Çelik, Knut Brockow, Lene H. Garvey, Inmaculada Doña, Jean‐Christoph Caubet, Francesca Mori, Jason Trubiano, Giorgia Marta, Antonino Romano, Ingrid Terreehorst, Asli Gelincik, Philip H. Li, Vito Sabato   +19 more
wiley   +1 more source

Epidemiological features of aplastic anaemia in Pakistan [PDF]

, 2001
Objective: To complete the data on the demographic features of patients diagnosed to have aplastic anemia at a single institution over a 7.5 years period. Methods: Demographic information was retrieved from the patients medical records retrospectively as
Adil, Salman, Burney, I. A., Khurshid, Mohammad, Kakepoto, G. N.   +3 more
core  

Regulatory T-cells in Acquired Aplastic Anaemia

, 2020
: Introduction: Acquired aplastic anaemia is characterized by destruction of haematopoietic stem cells by cytotoxic T lymphocytes. Regulatory T-cells have been reported to be suppressed in aplastic anaemia like many other autoimmune disorders ...
Maqsood, Sidra, Farzana, Tasneem, Shareef, Sumaira, Munzir, Saima, Shamsi, Tahir, Taj, Mehwesh   +5 more
core  

Low dose cyclosporine-a therapy in severe aplastic anaemia

, 2001
Objective : The present study was conducted to evaluate the efficacy of low dose cyclosporine-A in the patients of severe aplastic anaemia, who cannot afford allogenic bone marrow transplantation and immunosuppressive therapy with antithymocyte globulin ...
Jha, V. C., Rai, M., Singh, V. P., Shukla, J., Sundar, S.   +4 more
core   +2 more sources