Results 121 to 130 of about 340,068 (318)

Child with aplastic anemia: Anesthetic management

Saudi Journal of Anaesthesia, 2012
Aplastic anemia is a rare heterogeneous disorder of hematopoietic stem cells causing pancytopenia and marrow hypoplasia with the depletion of all types of blood cells.
Manpreet Kaur, Babita Gupta, Aanchal Sharma, Sanjeev Sharma   +3 more
doaj   +1 more source

Case Report: Hematopoietic Stem Cell Transplantation to Treat Severe Acquired Aplastic Anemia in a Pediatric Kidney Transplant Recipient [PDF]

Pediatr Transplant
ABSTRACT Background Hematopoietic stem cell transplantation (HSCT) in solid organ transplant recipients has been reported in adults. However, data on children are scarce. We report a case of an allogeneic HSCT in a 14‐year‐old girl to treat idiopathic very severe aplastic anemia (SAA). Case Presentation The girl developed end‐stage renal disease at the
Mierkienė G, Vaitkevičienė G, Ažukaitis K, Jankauskienė A, Rascon J.   +4 more
europepmc   +2 more sources

Quality-adjusted survival analysis shows differences in outcome after immunosuppression or bone marrow transplantation in aplastic anemia [PDF]

, 2018
Bone marrow transplantation (BMT) and immunosuppression (IS) have improved the prognosis of aplastic anemia; both treatments have specific advantages and drawbacks but similar survival rates.
Favre, Geneviève, Gratwohl, Alois, Gregor, Michael, Kühne, Thomas, Nissen, Catherine, Passweg, Jakob, Tichelli, André, Viollier, Romaine   +7 more
core  

Eltrombopag Added to Immunosuppression in Severe Aplastic Anemia

New England Journal of Medicine, 2022
R. Peffault de Latour, A. Kulasekararaj, S. Iacobelli, Sofie R Terwel, Riley Cook, M. Griffin, C. Halkes, C. Récher, F. Barraco, E. Forcade, J. Vallejo, B. Drexler, J. Mear, Alexander Smith, E. Angelucci, R. Raymakers, M. D. de Groot, É. Daguindau, E. Nur, W. Barcellini, N. Russell, L. Terriou, A. Iori, Ursula La Rocca, A. Sureda, I. Sánchez-Ortega, B. Xicoy, I. Jarque, J. Cavenagh, F. Sicre de Fontbrune, S. Marotta, T. Munir, J. Tjon, S. Tavitian, A. Praire, L. Clément, F. Rabian, L. Marano, A. Hill, E. Palmisani, P. Muus, F. Cacace, Camilla Frieri, M. V. van Lint, J. Passweg, J. Marsh, G. Socié, G. Mufti, C. Dufour, A. Risitano   +49 more
semanticscholar   +1 more source

Molecular pathogenesis of acquired aplastic anemia

European Journal of Haematology, 2018
The application of next‐generation sequencing (NGS) has enhanced our understanding of the genetic landscape in acquired aplastic anemia (AA). Parallel progress has been in addressing aspects underlying immune dysregulation in disease pathogenesis.
P. Boddu, T. Kadia
semanticscholar   +1 more source

Has early mortality following single‐unit unrelated cord blood transplantation improved in recent years? A nationwide registry data analysis from 2003 to 2022 in Japan

British Journal of Haematology, EarlyView.
The 100‐day non‐relapse mortality after single‐unit cord blood transplantation significantly declined from 19.6% (2003–2007) to 9.5% (2018–2022), while the 3‐year overall survival improved from 38.8% to 54.4%. Haematopoietic recovery rates improved steadily, with neutrophil engraftment reaching 89.6% and platelet engraftment 78.0% in the most recent ...
Takaaki Konuma, Junya Kanda, Naoyuki Uchida, Masatsugu Tanaka, Fumihiko Kimura, Hideki Nakasone, Yasufumi Uehara, Masahito Tokunaga, Masako Toyosaki, Shigesaburo Miyakoshi, Noriko Doki, Kazuya Ishiwata, Hikaru Kobayashi, Yasushi Onishi, Yasuji Kozai, Koji Kato, Fumihiko Ishimaru, Takahiro Fukuda, Yoshiko Atsuta, Satoshi Takahashi   +19 more
wiley   +1 more source

Perspective and Experience of Patients with Aplastic Anemia on Medication Adherence

Patient Preference and Adherence, 2023
Hangting Li,1,* Xiaolian Wu,1,* Jiaoni Shen,2 Shuhui Lou2 1Department of Hematology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, People’s Republic of China ...
Li H, Wu X, Shen J, Lou S
doaj  

Acute lymphoblastic leukemia of childhood presenting as aplastic anemia: report of two cases

Revista Brasileira de Hematologia e Hemoterapia, 2012
Acute lymphoblastic leukemia is the most common malignancy in pediatric patients; its diagnosis is usually easy to establish as malignant lymphoblasts invade the bone marrow and peripheral blood.
Laura Villarreal-Martínez, José Carlos Jaime-Pérez, Marisol Rodríguez-Martínez, Oscar González-Llano, David Gómez-Almaguer   +4 more
doaj   +1 more source

Eltrombopag mobilizes iron in patients with aplastic anemia.

Blood, 2018
TO THE EDITOR: The thrombopoietin receptor agonist eltrombopag (EPAG) has been shown to restore hematopoiesis in patients with severe aplastic anemia (SAA) refractory to immunosuppressive therapy and to significantly improve response rates when used in ...
Zhen Zhao, Qian Sun, L. Sokoll, M. Streiff, Zhe Cheng, Sophie Grasmeder, D. Townsley, N. Young, C. Dunbar, T. Winkler   +9 more
semanticscholar   +1 more source

Transcription‐coupled repair: tangled up in convoluted repair

The FEBS Journal, EarlyView.
In this review, we discuss recent findings derived from diverse genomic, biochemical and structural, imaging, and functional studies (B–E) that culminated in deep mechanistic insight (A) into the vital cellular process of transcription‐coupled nucleotide excision repair (TC‐NER).
Diana A. Llerena Schiffmacher, Yun Jin Pai, Alex Pines, Wim Vermeulen   +3 more
wiley   +1 more source