Results 151 to 160 of about 340,068 (318)

Life‐Threatening Cytopenias in a Jehovah's Witness Following CD19‐Directed Chimeric Antigen Receptor T Cell Therapy

eJHaem, Volume 6, Issue 4, August 2025.
ABSTRACT Here we report on a Jehovah's Witness (JW) patient who experienced profound and prolonged life‐threatening cytopenias following CD19‐targeted CAR T cell therapy, successfully managed with bloodless medicine strategies. This case highlights the potential risks of CAR T therapy, even in patients without known hematotoxicity risk factors.
Corinne J. Shamehdi, Christian A. Gordillo, Ahmed Sawas, Rodney Macedo, Markus Y. Mapara, Ran Reshef   +5 more
wiley   +1 more source

Incidence and outcome of acquired aplastic anemia: real-world data from patients diagnosed in Sweden from 2000–2011

Haematologica, 2017
A plastic anemia is a rare life-threatening disease. However, since the introduction of immunosuppressive therapy and allogeneic stem cell transplantation, the outcome has improved considerably, and the 5-year survival is reported to be 70–80% in ...
K. Vaht, Magnus Göransson, K. Carlson, Cecilia Isaksson, S. Lenhoff, A. Sandstedt, B. Uggla, J. Winiarski, P. Ljungman, M. Brune, P. Andersson   +10 more
semanticscholar   +1 more source

hTERT Increases TRF2 to Induce Telomere Compaction and Extend Cell Replicative Lifespan

Aging Cell, Volume 24, Issue 8, August 2025.
In contrast to the dogma that a subset of short telomeres initiates senescence, hTERT variants unable to maintain telomere length block senescence by stabilizing TRF2 via inhibiting upstream E3 ubiquitin ligases. This noncanonical hTERT function also compacts telomeres and blocks senescence‐associated DNA damage signaling. Cancer cells expressing hTERT
Nancy Adam, Yang Yang, Mahbod Djamshidi, Sara Seifan, Nicholas S. Y. Ting, Joel Glover, Nicolas Touret, Paul M. K. Gordon, K. V. Vineetha Warriyar, Hokan Krowicki, Christine Kim Garcia, Sharon A. Savage, Aaron A. Goodarzi, Duncan M. Baird, Tara L. Beattie, Karl Riabowol   +15 more
wiley   +1 more source

Quality control improvement at Jana DCS Sdn. Bhd. [PDF]

, 2020
Jana DCS Sdn. Bhd. is one of the companies that run the service of air conditioning system supply in Nusajaya, Johor, Malaysia. Quality improvement is one of the most important part when talking about a company, mostly companies that operate in service ...
Abd Wahab, Muhammad Badrul Amin, Mahmood, Salwa, Mohamad Rus, Mohamad Arif, Mustar, Muhamad Radzi, Raja Mamat, Tengku Nur Azila   +4 more
core  

Anchored Indirect Treatment Comparison Finds Comparable Effects of Pegcetacoplan and Iptacopan in Paroxysmal Nocturnal Haemoglobinuria

European Journal of Haematology, Volume 115, Issue 2, Page 125-133, August 2025.
ABSTRACT Background Paroxysmal nocturnal haemoglobinuria (PNH) is an ultra‐rare, acquired non‐malignant haematological disorder characterised by thrombosis risk, serious complications and debilitating symptoms in untreated patients. Objective This anchored indirect treatment comparison (ITC) evaluated efficacy data between proximal complement 3 ...
Regis Peffault de Latour, Austin Kulasekararaj, David Dingli, Koo Wilson, Piotr Wojciechowski, Zalmai Hakimi, Jameel Nazir, Barbara Czech, Peter Hillmen, Jeff Szer   +9 more
wiley   +1 more source

تعيين ميزان بقا و عوامل موثر بر آن در کودکان مبتلا به آنمی آپلاستيک اکتسابی [PDF]

, 2004
آنمی آپلاستيک يک سندرم بالينی به صورت پان سيتوپنی در خون محيطی است که در اثر کاهش يا عدم توليد سلولهای خونی، بدون وجود شواهدی از بيماری ديگر در مغز استخوان ايجاد می‌شود. اين بيماری به 2 شکل اکتسابی و ارثی(مانند آنمی فانکونی) وجود دارد.
آهنچی, نوید, انصاری, شهلا, ساده‌دل, روزبه   +2 more
core  

Systemic lupus erythematosis with severe aplastic anemia successfully treated with rituximab and antithymocyte globulin [PDF]

, 1969
Wenbin Liu, Zhiping Hu, Shengyun Lin, Jianghua He, Yuhong Zhou   +4 more
openalex   +1 more source

The Two Faces of Pediatric SCA2

European Journal of Neurology, Volume 32, Issue 8, August 2025.
We report 22 children with SCA2 and a review of the literature (20 patients). Two pediatric forms appear to be distinct (infantile and juvenile). Figure created with https://BioRender.com. ABSTRACT Introduction Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant neurological disease usually described in adults.
Nicolas Rive Le Gouard, Maissa G. Bah, Giulia Coarelli, Anna Heinzmann, Anne‐Laure Fauret, Jean‐Madeleine de Sainte‐Agathe, Cécile Cazeneuve, Anna Gerasimenko, Domitille Gras, Yline Capri, Mathilde Renaud, Bernard Brais, Cecile Grenenko, Alice Masurel, Patrick Berquin, Florence Jobic, Julia Métreau, Kumaran Deiva, Alexandra Afenjar, Victor Gravrand, Annie Lannuzel, Mathieu Anheim, Tobias Geis, Ute Hehr, Jennifer Madan Cohen, Béatrice Desnous, Anneke J. A. Kievit, Nadia Bahi‐buisson, Diana Rodriguez, Florence Renaldo, Claude Cances, David Devos, Chloé Angelini, Cyril Goizet, Claire Ewenczyk, Alexandra Durr, Cyril Mignot   +36 more
wiley   +1 more source

55 Oxymetholone Therapy of Aplastic Anemia [PDF]

, 1967
Donald M. Allen, Morris H. Fine, Thomas F. Necheles, William Dameshek, Sydney S. Gellis   +4 more
openalex   +1 more source

Design, implementation and evaluation of a model of care for patients with germline predisposition to haematological malignancy and bone marrow failure syndromes

Internal Medicine Journal, Volume 55, Issue 8, Page 1350-1359, August 2025.
Abstract Background The bone marrow failure syndromes (BMFS) are clinically heterogeneous conditions with both inherited and acquired etiologies. Optimal care is often challenged by the complexity of these disorders and gaps in healthcare delivery.
Lucy C. Fox, Erin Goode, Nicole Den Elzen, Lin Cheng, Laura Barth, Kelsey Man, Anna Jarmolowicz, Mary Panjari, Stephanie Best, Karin Thursky, Paul James, Ashish Bajel, David Ritchie, Piers Blombery   +13 more
wiley   +1 more source