Results 21 to 30 of about 339,316 (310)

Thrombopoietin Promotes Cell Proliferation and Attenuates Apoptosis of Aplastic Anemia Serum-Treated 32D Cells via Activating STAT3/STAT5 Signaling Pathway and Modulating Apoptosis-Related Mediators

open access: yesCell Transplantation, 2021
The present study aimed to investigate the effect and possible mechanism of recombinant human thrombopoietin (rhTPO) on mouse 32D cells (a mouse myeloid progenitor cell line) treated with serum from patients with aplastic anemia and to elucidate the ...
Juan Qian   +7 more
doaj   +1 more source

The prognosis in aplastic anemia [PDF]

open access: yesBlood, 1975
Abstract The biphasic shape of the survival curve of 99 patients with aplastic anemia suggested that there may be at least two subgroups of patients with this disease, one with a very short survival and another with a longer survival. Patients who survived for 4 mo or less after the first clinic visit (group A) were different from the ...
Darryl M. Williams   +3 more
openaire   +4 more sources

Epidemiology of aplastic anemia: a study of 1324 cases

open access: yesHematology, 2020
Objective: Prevalence of aplastic anemia (AA) is high in the Asian population. This study was done to explore the etiology and association of AA with various socio-economic and environmental factors.
P. Ahmed   +9 more
semanticscholar   +1 more source

Peri-Operative Anesthetic Management of a Patient with Aplastic Anemia for Total Hip Replacement: Case Report

open access: yesArchives of Anesthesia and Critical Care, 2022
Aplastic anemia is rare hematological disorder with approximate incidence 1.5-7 cases per million individuals per year. Osteonecrosis, a frequently seen in patients with aplastic anemia.
Shalvi Mahajan   +3 more
doaj   +1 more source

Iron metabolism of in­testinal mucosa in various blood diseases [PDF]

open access: yes, 1964
For the investigation of iron metabolism in the intestinal mucosa in various blood diseases, intestinal biopsy (duodenum) was performed on 10 healthy controls and 35 cases with various blood diseases.
Kimura, Ikuro   +2 more
core   +1 more source

Changes in trabecular bone, hematopoiesis and bone marrow vessels in aplastic anemia, primary osteoporosis, and old age [PDF]

open access: yes, 1987
Retrospective histologic analyses of bone biopsies and of post mortem samples from normal persons of different age groups, and of bone biopsies of age- and sex-matched groups of patients with primary osteoporosis and aplastic anemia show characteristic ...
B. Frisch   +30 more
core   +1 more source

Clinical recommendations for the diagnosis and treatment of aplastic anemia (2019 edition)

open access: yesRussian journal of hematology and transfusiology, 2020
Introduction. At the initiative of the Russian Hematology Society, the research group for the study of idiopathic aplastic anemia has developed clinical recommendations for the diagnosis and treatment of idiopathic aplastic anemia.Aim: to standardize ...
E. A. Mihailova   +12 more
semanticscholar   +1 more source

Eltrombopag in Aplastic Anemia [PDF]

open access: yesSeminars in Hematology, 2015
The treatment of aplastic anemia is currently with immunosuppressive therapy (IST) with anti-thymocyte globulin (ATG) and cyclosporine, to which two thirds of patients respond. However, a significant proportion of these responders relapse and many have persistent cytopenias. The management of these patients is challenging.
Cynthia E. Dunbar   +4 more
openaire   +3 more sources

Aplastic Crisis as Primary Manifestation of Systemic Lupus Erythematosus [PDF]

open access: yes, 2011
Aplastic crisis is an unusual feature of systemic lupus erythematosus (SLE). We report the case of a 54-year-old woman presenting with both (extravascular) Coombs-positive hemolytic anemia and laboratory findings of bone marrow hyporegeneration with ...
Alger M   +23 more
core   +1 more source

Postvaccination graft dysfunction/aplastic anemia relapse with massive clonal expansion of autologous CD8+ lymphocytes.

open access: yesBlood Advances, 2020
Acquired aplastic anemia is a T-cell–mediated autoimmune bone marrow aplasia, without a known etiologic trigger. Clonal expansion of CD8+ effector T lymphocytes can occur following vaccination and accompany graft dysfunction or aplastic anemia relapse.
Caitlin Ritz   +14 more
semanticscholar   +1 more source

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