Results 21 to 30 of about 23,352 (209)

The Monocytopenia of Aplastic Anemia [PDF]

Blood, 1973
Abstract Eight out of 22 patients with aplastic anemia died from infections. All five patients with fewer than 100 granulocytes and 20 monocytes per cu mm of blood succumbed to overwhelming sepsis. The relationship that existed between absolute granulocyte and monocyte counts made it impossible to determine whether neutropenia or ...
J J, Twomey, C C, Douglass, O, Sharkey
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Therapy for Aplastic Anemia [PDF]

Hematology, 2011
Abstract A 24-year-old man from Ecuador presents to your clinic with dyspnea on exertion, bruising, and petechiae. He is noted to be pancytopenic with ANC 430, hemoglobin 7.4 g/dL (reticulocyte count 0.9%), and platelets 18 000. His BM biopsy is hypocellular for age. Ultimately, he is diagnosed with severe aplastic anemia. He is the only
Amy E, DeZern, Eva C, Guinan
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Eltrombopag in Aplastic Anemia [PDF]

Seminars in Hematology, 2015
The treatment of aplastic anemia is currently with immunosuppressive therapy (IST) with anti-thymocyte globulin (ATG) and cyclosporine, to which two thirds of patients respond. However, a significant proportion of these responders relapse and many have persistent cytopenias. The management of these patients is challenging.
Ronan, Desmond, Danielle M, Townsley, Cynthia, Dunbar, Neal S, Young   +3 more
openaire   +2 more sources

Aplastic anemia in the elderly: a nationwide survey on behalf of the French Reference Center for Aplastic Anemia

Haematologica, 2019
Aplastic anemia is a rare but potentially life-threatening disease that may affect older patients. Data regarding the treatment of aplastic anemia in this ageing population remains scarce.
Adrien Contejean, Matthieu Resche-Rigon, Jérôme Tamburini, Marion Alcantara, Fabrice Jardin, Etienne Lengliné, Lionel Adès, Didier Bouscary, Ambroise Marçais, Delphine Lebon, Cécile Chabrot, Louis Terriou, Fiorenza Barraco, Anne Banos, Lucile Bussot, Jean-Yves Cahn, Pierre Hirsch, Natacha Maillard, Laurence Simon, Luc-Matthieu Fornecker, Gerard Socié, Regis Peffault de Latour, Flore Sicre de Fontbrune   +22 more
doaj   +1 more source

Incidence and risk factors of aplastic anemia in Latin American countries: the LATIN case-control study

Haematologica, 2009
Background Associations between aplastic anemia and numerous drugs, pesticides and chemicals have been reported. However, at least 50% of the etiology of aplastic anemia remains unexplained.Design and Methods This was a case-control, multicenter ...
Eliane Maluf, Nelson Hamerschlak, Alexandre Biasi Cavalcanti, Álvaro Avezum Júnior, José Eluf-Neto, Roberto Passetto Falcão, Irene G. Lorand-Metze, Daniel Goldenberg, Cézar Leite Santana, Daniela de Oliveira Werneck Rodrigues, Leny Nascimento da Motta Passos, Luis Gastão Mange Rosenfeld, Marimilia Pitta, Sandra Loggetto, Andreza A. Feitosa Ribeiro, Elvira Deolinda Velloso, Andrea Tiemi Kondo, Erika Oliveira de Miranda Coelho, Maria Carolina Tostes Pintão, Hélio Moraes de Souza, José Rafael Borbolla, Ricardo Pasquini   +21 more
doaj   +1 more source

Aplastic Anemia in a Developing Country: The Present and the Need [PDF]

National Journal of Laboratory Medicine, 2016
Introduction: Aplastic anemia (AA) a rare, yet a life threatening hematological disorder. Aplastic anemia if untreated results in very high mortality. Early diagnosis of Aplastic anemias is essential for appropriate management of the patient.
Ashwini BR , Seetu Palo, Siddiq M Ahmed
doaj   +1 more source

Successful treatment of severe aplastic anemia with syngeneic stem cell transplantation in the setting of active disseminated mucormycosis

Medical Mycology Case Reports, 2019
Severe aplastic anemia (SAA) is a hematological disease resulting in pancytopenia due to bone marrow failure. Treatment consists of immunosppressive therapy, or allo-SCT.
Jean El-Cheikh, Ali Atoui, Nour Moukalled, Nohra Ghaoui, Haidar El Darsa, Souha S. Kanj, Ali Bazarbachi   +6 more
doaj   +1 more source

Circulating thrombopoietin levels in normal healthy blood donors and in aplastic anemia patients in relation to disease severity

Asian Journal of Transfusion Science, 2015
Background: Thrombopoietin (TPO) is the key hematopoietic growth factor regulating the production of platelets from bone marrow megakaryocytes and maintaining platelet hemostasis.
Abhay Singh, Anupam Verma, Soniya Nityanand, Rajendra Chaudhary, Priti Elhence   +4 more
doaj   +1 more source

Proposed protocol for treatment of severe periodontitis without platelet transfusion in patients with aplastic anemia: a case report

Journal of Medical Case Reports, 2021
Background Aplastic anemia is an intractable disease characterized by pancytopenia, susceptibility to infection, and difficulty in achieving hemostasis.
Satoru Morikawa, Kazuya Watanabe, Satoshi Usuda, Yoko Miyashita, Taneaki Nakagawa   +4 more
doaj   +1 more source

A plasma microRNA signature as a biomarker for acquired aplastic anemia

Haematologica, 2017
Aplastic anemia is an acquired bone marrow failure characterized by marrow hypoplasia, a paucity of hematopoietic stem and progenitor cells, and pancytopenia of the peripheral blood, due to immune attack on the bone marrow.
Kohei Hosokawa, Sachiko Kajigaya, Xingmin Feng, Marie J. Desierto, Maria del Pilar Fernandez Ibanez, Olga Rios, Barbara Weinstein, Phillip Scheinberg, Danielle M. Townsley, Neal S. Young   +9 more
doaj   +1 more source