Results 21 to 30 of about 193,360 (208)

Circulating thrombopoietin levels in normal healthy blood donors and in aplastic anemia patients in relation to disease severity

Asian Journal of Transfusion Science, 2015
Background: Thrombopoietin (TPO) is the key hematopoietic growth factor regulating the production of platelets from bone marrow megakaryocytes and maintaining platelet hemostasis.
Abhay Singh, Anupam Verma, Soniya Nityanand, Rajendra Chaudhary, Priti Elhence   +4 more
doaj   +1 more source

Proposed protocol for treatment of severe periodontitis without platelet transfusion in patients with aplastic anemia: a case report

Journal of Medical Case Reports, 2021
Background Aplastic anemia is an intractable disease characterized by pancytopenia, susceptibility to infection, and difficulty in achieving hemostasis.
Satoru Morikawa, Kazuya Watanabe, Satoshi Usuda, Yoko Miyashita, Taneaki Nakagawa   +4 more
doaj   +1 more source

A plasma microRNA signature as a biomarker for acquired aplastic anemia

Haematologica, 2017
Aplastic anemia is an acquired bone marrow failure characterized by marrow hypoplasia, a paucity of hematopoietic stem and progenitor cells, and pancytopenia of the peripheral blood, due to immune attack on the bone marrow.
Kohei Hosokawa, Sachiko Kajigaya, Xingmin Feng, Marie J. Desierto, Maria del Pilar Fernandez Ibanez, Olga Rios, Barbara Weinstein, Phillip Scheinberg, Danielle M. Townsley, Neal S. Young   +9 more
doaj   +1 more source

Cyclosporine A and Romiplostim as a Bridging Therapy to Curative Surgery in Aplastic Anemia Complicated by Gastric Cancer: A Case Report. [PDF]

EJHaem
ABSTRACT We present a case of aplastic anemia (AA) complicated with gastric cancer that was successfully treated with cyclosporine A (CsA) and romiplostim (ROMI) as a bridging therapy before curative surgery. This patient had untreated gastric cancer at the time of AA diagnosis, and surgery was difficult because of thrombocytopenia.
Nakagawa N, Yamazaki M, Hosokawa K.
europepmc   +2 more sources

ELTROMBOPAG THERAPHY IN CASES OF APLASTIC ANEMIA: A CASE REPORT

, 2023
: Eltrombopag Theraphy In Cases Of Aplastic Anemia: A Case Report. Management of cases of aplastic anemia is challenge. The definitive treatment is bone marrow transplantation, but it is expensive, the complication rate is high and the success rate is ...
Suastika, Ngakan Ketut Wira, Wisadianta, Gede Resha   +1 more
core   +1 more source

Severe retinal hemorrhages at various levels with a serous retinal detachment in a pediatric patient with aplastic anemia–A case report

Frontiers in Medicine, 2023
BackgroundAplastic anemia can cause ophthalmic abnormalities in patients. Vision loss in a child with aplastic anemia due to massive retinal hemorrhages at various levels is rare.Case presentationA pediatric patient with aplastic anemia presented with ...
Xiaoshuang Jiang, Mengxi Shen, Licong Liang, Philip J. Rosenfeld, Fang Lu   +4 more
doaj   +1 more source

Thymoma followed by aplastic anemia: two different responses to immunosuppressive therapy

Revista Brasileira de Hematologia e Hemoterapia, 2011
Aplastic anemia is an uncommon complication of thymoma and is extremely infrequent after the surgical removal of a thymic tumor. Aplastic anemia is a result of marrow failure and is characterized by peripheral pancytopenia and severely depressed marrow ...
Murilo Antunes de Castro, Mariana Antunes de Castro, Adriano de Moraes Arantes, Maria do Rosário Ferraz Roberti   +3 more
doaj   +1 more source

Syngeneic peripheral blood stem cell transplantation with immunosuppression for hepatitis-associated severe aplastic anemia

Turkish Journal of Hematology, 2010
Hepatitis-associated aplastic anemia occurs in up to 10% of all aplastic anemia cases. Syngeneic bone marrow transplantation is rare in patients with severe aplastic anemia and usually requires pre-transplant conditioning to provide engraftment.
Aleksandar Savic, Bela Balint, Ivana Urosevic, Nebojsa Rajic, Milena Todorovic, Ivanka Percic, Stevan Popovic   +6 more
doaj   +3 more sources

Myelodysplastic syndrome evolving from aplastic anemia treated with immunosuppressive therapy: efficacy of hematopoietic stem cell transplantation

Haematologica, 2014
A proportion of patients with aplastic anemia who are treated with immunosuppressive therapy develop clonal hematologic disorders, including post-aplastic anemia myelodysplastic syndrome.
Sung-Yong Kim, Jennifer Le Rademacher, Joseph H. Antin, Paolo Anderlini, Mouhab Ayas, Minoo Battiwalla, Jeanette Carreras, Joanne Kurtzberg, Ryotaro Nakamura, Mary Eapen, H. Joachim Deeg   +10 more
doaj   +1 more source

Effectiveness of Iptacopan Versus C5 Inhibitors in Complement Inhibitor‐Naive Patients With Paroxysmal Nocturnal Haemoglobinuria

eJHaem
Background Paroxysmal nocturnal haemoglobinuria (PNH) is characterised by haemolytic anaemia, bone marrow failure and thrombosis. The single‐arm phase 3 APPOINT‐PNH trial (NCT04820530) investigating iptacopan monotherapy in complement inhibitor‐naive ...
Matthew Holt, Richard J. Kelly, Jilles M. Fermont, Soudeh Ansari, Marion Dahlke, Isabelle Brindel, Lynda Maafa, Flore Sicre deFontbrune, Régis Peffault deLatour   +8 more
doaj   +1 more source