Results 21 to 30 of about 181,406 (245)
Vnitřní lékařství, 2018 Aplastic anemia - bone marrow failure (AA) is defined as pancytopenia with hypocellular bone marrow without signs of marrow fibrosis or of presence of abnormal cells. Recent studies showed that most of AA cases might be mediated by immune mechanisms.
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Current Opinion in Internal Medicine, 2008 Most acquired aplastic anemia is the result of immune-mediated destruction of hematopoietic stem cells causing pancytopenia and an empty bone marrow, which can be successfully treated with either immunosuppressive therapy or hematopoietic stem-cell transplantation.In aplastic anemia, oligoclonally expanded cytotoxic T cells induce apoptosis of ...
Neal S, Young +2 more
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Archives of Anesthesia and Critical Care, 2022 Aplastic anemia is rare hematological disorder with approximate incidence 1.5-7 cases per million individuals per year. Osteonecrosis, a frequently seen in patients with aplastic anemia.
Shalvi Mahajan +3 more
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Cell Transplantation, 2021 The present study aimed to investigate the effect and possible mechanism of recombinant human thrombopoietin (rhTPO) on mouse 32D cells (a mouse myeloid progenitor cell line) treated with serum from patients with aplastic anemia and to elucidate the ...
Juan Qian +7 more
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Aplastic anemia in China [PDF]
Journal of Translational Internal Medicine, 2018 Abstract Aplastic anemia (AA) is a hematologic disease characterized by pancytopenia. Up to now, severe aplastic anemia (SAA) has been recognized by international and domestic scholars as an autoimmune disease with bone marrow (BM) failure mediated by the hyperfunctional T lymphocytes.
Liu, Chunyan, Shao, Zonghong
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Profil Penderita Anemia Aplastik di RSUP Dr. M. Djamil Padang Tahun 2018-2019
Jurnal Ilmu Kesehatan Indonesia, 2021 Background. Aplastic anemia is a failure of the process of formation and development of blood cells that causes a decrease or absence of hematopoietic precursor cells in the bone marrow.
Amanda Rizki +2 more
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A mutation in a functional Sp1 binding site of the telomerase RNA gene (hTERC) promoter in a patient with Paroxysmal Nocturnal Haemoglobinuria [PDF]
, 2004 Background<br/><br/> Mutations in the gene coding for the RNA component of telomerase, hTERC, have been found in autosomal dominant dyskeratosis congenita (DC) and aplastic anemia.
Ulku, B. +47 more
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The Monocytopenia of Aplastic Anemia [PDF]
Blood, 1973 Abstract Eight out of 22 patients with aplastic anemia died from infections. All five patients with fewer than 100 granulocytes and 20 monocytes per cu mm of blood succumbed to overwhelming sepsis. The relationship that existed between absolute granulocyte and monocyte counts made it impossible to determine whether neutropenia or ...
J J, Twomey, C C, Douglass, O, Sharkey
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Haematologica, 2019 Aplastic anemia is a rare but potentially life-threatening disease that may affect older patients. Data regarding the treatment of aplastic anemia in this ageing population remains scarce.
Adrien Contejean +22 more
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Pathogenesis of aplastic anemia [PDF]
Hematology, 2019 Aplastic anemia (AA) is a rare and life-threatening bone marrow failure (BMF) that results in peripheral blood cytopenia and reduced bone marrow hematopoietic cell proliferation. The symptoms are similar to myelofibrosis, myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) making diagnosis of AA complicated.
Li, Wang, Hong, Liu
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