Results 21 to 30 of about 42,500 (221)

Successful treatment of severe aplastic anemia with syngeneic stem cell transplantation in the setting of active disseminated mucormycosis

Medical Mycology Case Reports, 2019
Severe aplastic anemia (SAA) is a hematological disease resulting in pancytopenia due to bone marrow failure. Treatment consists of immunosppressive therapy, or allo-SCT.
Jean El-Cheikh, Ali Atoui, Nour Moukalled, Nohra Ghaoui, Haidar El Darsa, Souha S. Kanj, Ali Bazarbachi   +6 more
doaj   +1 more source

The differentiation of cholesterol and pigment gallstones [PDF]

, 1989
Gallbladder biles and stones were obtained at 116 cholecystectomies for symptomatic gallstone disease. All 33 patients younger than 50 years had cholesterol stones, whereas 40% of the older patients had pigment stones.
Carey, Holan, Pomeranz, Sackmann, Thistle, Trotman   +5 more
core   +1 more source

Circulating thrombopoietin levels in normal healthy blood donors and in aplastic anemia patients in relation to disease severity

Asian Journal of Transfusion Science, 2015
Background: Thrombopoietin (TPO) is the key hematopoietic growth factor regulating the production of platelets from bone marrow megakaryocytes and maintaining platelet hemostasis.
Abhay Singh, Anupam Verma, Soniya Nityanand, Rajendra Chaudhary, Priti Elhence   +4 more
doaj   +1 more source

Proposed protocol for treatment of severe periodontitis without platelet transfusion in patients with aplastic anemia: a case report

Journal of Medical Case Reports, 2021
Background Aplastic anemia is an intractable disease characterized by pancytopenia, susceptibility to infection, and difficulty in achieving hemostasis.
Satoru Morikawa, Kazuya Watanabe, Satoshi Usuda, Yoko Miyashita, Taneaki Nakagawa   +4 more
doaj   +1 more source

Tianshengyuan-1 (TSY-1) regulates cellular Telomerase activity by methylation of TERT promoter. [PDF]

, 2016
Telomere and Telomerase have recently been explored as anti-aging and anti-cancer drug targets with only limited success. Previously we showed that the Chinese herbal medicine Tianshengyuan-1 (TSY-1), an agent used to treat bone marrow deficiency, has a ...
Chow, Michelle, Jin, Yusheng, Li, Yawei, Qin, Xiaotian, Rao, Jianyu, Santiskulvong, Chintda, Vu, Victor, Yu, Weibo, Zeng, Gang, Zhang, Zuofeng   +9 more
core   +2 more sources

p53 mediates failure of human definitive hematopoiesis in dyskeratosis congenita [PDF]

, 2017
Summary: Dyskeratosis congenita (DC) is a bone marrow failure syndrome associated with telomere dysfunction. The progression and molecular determinants of hematopoietic failure in DC remain poorly understood.
Batista, Luis Francisco Zirnberger, Brenner, Kirsten Ann, Dege, Carissa, Fok, Wilson Chun, Niero, Evandro Luis de Oliveira, Sturgeon, Christopher Michael   +5 more
core   +3 more sources

A plasma microRNA signature as a biomarker for acquired aplastic anemia

Haematologica, 2017
Aplastic anemia is an acquired bone marrow failure characterized by marrow hypoplasia, a paucity of hematopoietic stem and progenitor cells, and pancytopenia of the peripheral blood, due to immune attack on the bone marrow.
Kohei Hosokawa, Sachiko Kajigaya, Xingmin Feng, Marie J. Desierto, Maria del Pilar Fernandez Ibanez, Olga Rios, Barbara Weinstein, Phillip Scheinberg, Danielle M. Townsley, Neal S. Young   +9 more
doaj   +1 more source

Invasive bacterial infections in Gambians with sickle cell anaemia in an era of widespread Pneumococcal and Haemophilus influenzae type B vaccination [PDF]

, 2016
Background: There is relatively little data on the aetiology of bacterial infections in patients with sickle cell anaemia (SCA) in West Africa, and no data from countries that have implemented conjugate vaccines against both Streptococcus pneumoniae and ...
Anderson, ST, Bah, G, Cunnington, A, Darboe, S, Lawal, B, Soothill, G   +5 more
core   +1 more source

Aplastic anemia associated to systemic lupus erythematosus in an AIDS patient: a case report

Revista Brasileira de Hematologia e Hemoterapia, 2013
Aplastic anemia is a bone marrow failure syndrome characterized by peripheral cytopenias and hypocellular bone marrow. Although aplastic anemia is idiopathic in most cases, rheumatic diseases such as systemic lupus erythematosus are recognized as causes ...
Leonardo Rodrigues de Oliveira, Thais Camargos Ferreira, Fernando de Freitas Neves, Antonio Carlos de Oliveira Meneses   +3 more
doaj   +1 more source

Severe retinal hemorrhages at various levels with a serous retinal detachment in a pediatric patient with aplastic anemia–A case report

Frontiers in Medicine, 2023
BackgroundAplastic anemia can cause ophthalmic abnormalities in patients. Vision loss in a child with aplastic anemia due to massive retinal hemorrhages at various levels is rare.Case presentationA pediatric patient with aplastic anemia presented with ...
Xiaoshuang Jiang, Mengxi Shen, Licong Liang, Philip J. Rosenfeld, Fang Lu   +4 more
doaj   +1 more source