Results 91 to 100 of about 85,673 (310)

Unless Someone Like You Cares a Whole Awful Lot: Apocalypse as Children’s Entertainment [PDF]

open access: yes, 2017
This article explores an unusual subset of children’s narrative, the apocalyptic environmentalist text, and argues that such texts perform the perverse ideological work of shifting blame for ecological crisis from its perpetrators (the parents ...
Canavan, Gerry
core   +1 more source

The Subversion of the Apocalypses in the Book of Jubilees [PDF]

open access: yes, 2012
In spite of some scholars’ inclination to include the book of Jubilees as another witness to “Enochic Judaism,” the relationship of Jubilees to the apocalyptic writings and events surrounding the Maccabean revolt has never been adequately clarified. This
Todd Hanneken
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Wittgenstein and the Possibility of Religious Belief [PDF]

open access: yes, 2003
Contemporary philosophers of religion delimiting their field\ud often distinguish between belief in and belief that, and then\ud focus on the latter as more pertinent to a philosophical\ud investigation of religious belief.
Sayre, Patricia
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Un studiu intertextual asupra cântecului Anei din Targumul Profeților (1 Sam. 2:1–10) și al secțiunii aramaice din cartea Daniel (Dan. 2–7) [An Intertextual Study of the Song of Anna from the Targum of the Prophets (1 Sam. 2:1–10) and the Aramaic … ]

open access: yesTheoRhēma, 2015
The aim of this study is to single out possible intertextual connections between the Song of Hannah in the Targums to the Prophets and the Aramaic section of the Book of Daniel.
Daniel Olariu
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

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