Results 91 to 100 of about 85,328 (309)

Postmodern teleological agents of end in Don DeLilLos White Noise [PDF]

open access: yes, 2015
Apocalyptic literature in its secular form is a rich way of depicting a more meaningful fiction about ateleological end. The aim of postmodern apocalyptic literature is to manifest how the need for structure inspiresthe writers of this genre to use it as
Jujar Singh, Hardev Kaur   +1 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Un studiu intertextual asupra cântecului Anei din Targumul Profeților (1 Sam. 2:1–10) și al secțiunii aramaice din cartea Daniel (Dan. 2–7) [An Intertextual Study of the Song of Anna from the Targum of the Prophets (1 Sam. 2:1–10) and the Aramaic … ]

open access: yesTheoRhēma, 2015
The aim of this study is to single out possible intertextual connections between the Song of Hannah in the Targums to the Prophets and the Aramaic section of the Book of Daniel.
Daniel Olariu
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Defining and Distinguishing Secular and Religious Terrorism

open access: yesPerspectives on Terrorism, 2014
Religious terrorism is typically characterised as acts of unrestrained, irrational and indiscriminant violence, thus offering few if any policy options for counterterrorism measures.
Heather S. Gregg
doaj  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

THE SINGULARITY AND THE RAPTURE: TRANSHUMANIST AND POPULAR CHRISTIAN VIEWS OF THE FUTURE

open access: yesZygon, 2012
Religious views of the future often include detailed expectations of profound changes to nature and humanity. Popular American evangelical Christianity, especially writers like Hal Lindsey, Rick Warren, or Rob Bell, offer extended accounts that provide ...
doaj   +2 more sources

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