Results 71 to 80 of about 19,104 (309)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Versoening in Joodse apokaliptiese literatuur

open access: yesVerbum et Ecclesia, 2005
Before the discussion of the subject of reconciliation in apocalyptic literature can be researched it is necessary to answer preliminary questions: What is apocalyptic literature? Where, how and why did it originate?
M Nel
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The Life Course of Apocalyptic Groups

open access: yesJournal of Strategic Security, 2018
Apocalyptic groups have launched attacks in the past, which if competently executed, would have been catastrophic. The security community needs a greater understanding of when law enforcement or the military should intercept dangerous apocalyptic groups.
Karl Umbrasas
doaj   +1 more source

Global Catastrophe in Motion Pictures as Meaning and Message: The Functions of Apocalyptic Cinema in American Film

open access: yesJournal of Religion & Film, 2017
The Rising Popularity of Apocalyptic CinemaFilms with apocalyptic themes have never been more popular. John Walliss and James Aston report that the 21st Century has seen a significant increase in the number of films having an apocalyptic theme.1 Mary ...
Wynn Gerald Hamonic
semanticscholar   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Vyandigheid in apokaliptiese literatuur – die Daniëlboek

open access: yesIn die Skriflig, 2006
Animosity in apocalyptic literature – the Book of Daniel What is reflected in apocalyptic literature about the subject of animosity? Apocalyptic literature is limited in this article to the Book of Daniel, because it is the most extended apocalyptic ...
Marius Nel
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Japanese Apocalyptic Dystopia and the Role of Steampunk in Hayao Miyazaki’s Howl’s Moving Castle

open access: yesFafnir, 2019
Japanese film director, screenwriter, and animator Hayao Miyazaki created an intricate adaptation of Diana Wynne Jones’s fantasy novel Howl’s Moving Castle (1986). Both the 2004 eponymous Japanese anime film and the novel seem to be set in the Edwardian
Petra Visnyei
doaj  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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