Results 61 to 70 of about 14,288 (309)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Apocalyptic Mind [PDF]

open access: yesThe Biblical World, 1920
a new era, apocalypticism celebrates a revival of devoted enthusiasm. Wars, floods, epidemics, earthquakes, uncertainty, social revolution, industrial upheaval, rumors, suspense-these and their kin nourish the apocalyptic fever. Consequently, the last half decade has witnessed the production of innumerable weird and uncanny calendars of the immediate ...
openaire   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The Post-Apocalyptic Turn: a Study of Contemporary Apocalyptic and Post-Apocalyptic Narrative

open access: yes, 2014
Few periods have witnessed so strong a cultural fixation on apocalyptic calamity as the present. From fictions and comic books to Hollywood films, television shows, and video games, the end of the world is ubiquitous in the form of apocalyptic and post ...
Moon, Hyong-jun
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Critical Temporalities: Station Eleven and the Contemporary Post-Apocalyptic Novel

open access: yesOpen Library of Humanities, 2018
This article examines Emily St. John Mandel’s Station Eleven (2014) in the context of the growing body of contemporary post-apocalyptic fictions and what I argue is their critique of the apocalyptic tradition.
Diletta De Cristofaro
doaj   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

The Dawn of Apocalyptic: The Historical and Sociological Roots of Jew-ish Apocalyptic Eschatology

open access: yes, 2023
RESENHA ACADÊMICAHANSON, Paul D.. The Dawn of Apocalyptic: The Historical and Sociological Roots of Jewish Apocalyptic Eschatology. Revised Edition. Philadelphia: Fortress Press, 2012. 444 pp. ISBN 978-08-006-1809-
da Silva, Ângelo Vieira
core   +1 more source

Versoening in Joodse apokaliptiese literatuur

open access: yesVerbum et Ecclesia, 2005
Before the discussion of the subject of reconciliation in apocalyptic literature can be researched it is necessary to answer preliminary questions: What is apocalyptic literature? Where, how and why did it originate?
M Nel
doaj   +1 more source

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