Results 61 to 70 of about 102,450 (165)

Proteomic analysis in hidradenitis suppurativa reveals systemic inflammation in all disease stages

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Proteomic profiling reveals systemic inflammation in patients with hidradenitis suppurativa, even in early disease. Distinct mediators (e.g. TGF‐α, OSM, HGF) are elevated early, whereas others correlate with clinical severity (e.g. IL‐6, VEGF‐A, IL‐17A) or disease duration (e.g.
Lotta Sandelin Francke, Ansam Al‐Bayatti, Hanqian Zhang, Mohammad Alimohammadi, Hans Törmä, Enikö Sonkoly   +5 more
wiley   +1 more source

Giant apocrine hidrocystoma of the scrotum: An uncommon benign tumor at an exceptional site

Acta Marisiensis - Seria Medica
Introduction: Apocrine hidrocystoma (AH) is a rare, benign cystic tumour of apocrine glands, typically occurring in adults between 30 and 70 years of age without gender predilection.
Dorić Mirsad, Čamdžić Nina
doaj   +1 more source

Safety and pharmacokinetics of anumigilimab for hidradenitis suppurativa or palmoplantar pustulosis: A phase 1b study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Anumigilimab, a novel anti‐G‐CSF receptor antibody, was investigated in a phase 1b trial involving 39 patients with hidradenitis suppurativa or palmoplantar pustulosis. No serious safety concerns related to anumigilimab were noted, and PK and PD were dose dependent.
Johannes S. Kern, Simon Francis Thomsen, Georgios Kokolakis, Maurizio Podda, Gregor B. E. Jemec, Kurt Gebauer, Claus Zachariae, John Frew, Pablo Fernandez‐Peñas, Falk G. Bechara, Stefan Beissert, Sourabh Malandkar, Karen Scalzo‐Inguanti, Partha Nandy, Selvakumar Sukumar   +14 more
wiley   +1 more source

European S2k guidelines for hidradenitis suppurativa/acne inversa Part 1. Epidemiology, diagnosis and clinical assessment

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Updated S2k hidradenitis suppurativa (HS) guidelines provide expert consensus on diagnosis, assessment and comorbidities. Expanded substantially since the 2015 version, they reflect rapid growth in HS literature and aim to improve generalist‐level patient care through evidence‐informed, consensus‐based guidance.
G. B. E. Jemec, B. Villumsen, K. R. van Straalen, H. H. van der Zee, S. Valiukevičienė, T. Tzellos, J. C. Szepietowski, A. Szegedi, D. M. L. Saunte, M. Romanelli, H. Raynal, F. Prignano, E. P. Prens, M. Podda, A. Nassif, A. Molina‐Leyva, Ł. Matusiak, A. V. Marzano, B. M. McGrath, A. I. Liakou, B. Kirby, L. Kemény, E. Just, D. Ioannidis, J. R. Ingram, R. E. Hunger, B. Horváth, P. Guillem, Ø. Grimstad, E. J. Giamarellos‐Bourboulis, M. Dolenc‐Voljč, V. Del Marmol, Z. Bukvić Mokos, V. Bettoli, F. Benhadou, F. G. Bechara, C. C. Zouboulis   +36 more
wiley   +1 more source

PACAP activated adenylate cyclase in human sweat glands. An ultracytochemical study

European Journal of Histochemistry, 2010
The ultracytochemical localization of adenylate cyclase (AC) was studied after stimulation with pituitary adenylate cyclase activating peptide (PACAP) in human sweat glands. PACAP stimulated AC in both eccrine and apocrine glands. In the secretory cells,
MG Rambotti, S Simonetti, A Spreca
doaj   +1 more source

Survival outcomes in dogs treated with vinorelbine‐based adjuvant treatment following surgical resection of grade II and III pulmonary carcinoma

Journal of Small Animal Practice, EarlyView.
Objectives Pulmonary carcinoma in dogs is commonly managed with surgical resection; however, the role of adjuvant chemotherapy for grade II and III carcinomas remains unclear. This retrospective multicentre study investigated the outcomes in dogs treated with vinorelbine‐based adjuvant treatment (as monotherapy or combined chemotherapy) following ...
N. Wong, L. Brockley, S. Rajan, J. Yu
wiley   +1 more source

A dose‐escalated radiation protocol of 10 × 4.0 Gy provides long‐term local control in canine apocrine gland anal sac adenocarcinoma

Journal of Small Animal Practice, EarlyView.
Objectives To obtain insights for establishing radiation therapy strategies that provide long‐term locoregional benefits in canine apocrine gland anal sac adenocarcinoma, we evaluated whether a dose‐escalated protocol (10 × 4.0 Gy) could improve clinical outcomes, particularly long‐term locoregional control, while maintaining acceptable toxicity ...
M. Terauchi, Y. Fujii, R. Iwasaki, T. Mori   +3 more
wiley   +1 more source

Apocrine hidrocystomas: An unusual case presentation and review of literature

Journal of Dermatology and Dermatologic Surgery, 2019
Apocrine hidrocystomas (AHs) are cystic benign lesions of the skin that originates from the apocrine sweat glands. It is usually solitary and occasionally multiple. Herein, we report an unusual case of multiple apocrine hidrocystomas. A 65-year-old Saudi
Khalid Ali Al Hawsawi, Luai Mohammed Assaedi, Amnah Gefri, Rahaf Bukhari   +3 more
doaj   +1 more source

Assessment of Clinical and Immunological Factors of Local Recurrence in Canine Soft Tissue Sarcoma

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Canine soft tissue sarcomas (STSs) are locally invasive tumours, making local recurrence a major clinical challenge. Time to recurrence (TTR) and associated immune factors remain poorly characterized. This study aimed to characterize the immune microenvironment of canine STS and identify factors associated with TTR.
Kazuki Mizuta, Helene Philibert, Arata Matsuyama   +2 more
wiley   +1 more source

Ruptured intracranial dermoid: Case report and literature review

Medical Journal of Dr. D.Y. Patil University, 2017
Intracranial dermoid cysts are nonneoplastic, ectodermal inclusion cysts of embryological origin. They contain various ectodermal derivatives including apocrine glands, sebaceous glands, hairs, squamous epithelium, and occasionally teeth.
Pravin Tukaram Survashe, Sachin Parshuram Guthe, Vernon Velho, Anuj Bhide   +3 more
doaj   +1 more source