Results 111 to 120 of about 159,989 (316)

Cholesterol–sphingomyelin interaction in membrane and apolipoprotein-mediated cellular cholesterol efflux

Journal of Lipid Research, 2000
Helical apolipoproteins interact with cellular surface and generate high density lipoprotein (HDL) by removing phospholipid and cholesterol from cells.
Jin-ichi Ito, Yuko Nagayasu, Shinji Yokoyama   +2 more
doaj   +1 more source

Uptake mechanism of ApoE-modified nanoparticles on brain capillary endothelial cells as a blood-brain barrier model

, 2012
Background: The blood-brain barrier (BBB) represents an insurmountable obstacle for most drugs thus obstructing an effective treatment of many brain diseases.
Tikva Vogel, Zensi, Anja, von Briesen Hagen, Kreuter Jörg, Worek Franz, Tschickardt, Sabrina E., Sascha L Wien, Jörg Kreuter, Wien Sascha L., Vogel Tikva, Sabrina E Tschickardt, Wladislaw Maier, Vogel, Tikva, Sylvia Wagner, Claus U Pietrzik, Maier Wladislaw, Zensi Anja, Wien, Sascha L., Maier, Wladislaw, Tschickardt Sabrina E., Wagner, Sylvia, Pietrzik Claus U., Anja Zensi, Kreuter, Jörg, Worek, Franz, Hagen von Briesen, Pietrzik, Claus Ulrich, Briesen, Hagen von, Wagner Sylvia, Franz Worek   +29 more
core   +1 more source

Retardation of atherosclerosis in immunocompetent apolipoprotein (apo) E-deficient mice followingliver-directed administration of a [E1-, E3-,polymerase-] adenovirus vector containing the elongation factor-1a promoter driving expression of human apoE cDNA

, 2005
Although gene transfer of human apolipoprotein E (apoE), a 34-kDa circulating glycoprotein, to the liver of apoEdeficient(apoE-/-) mice using recombinant adenoviral vectors (rAd) is antiatherogenic, its full therapeutic potentialhas yet to be realized ...
Stannard, AK, Amalfitano, A, Owen, JS, Dickson, G, Schepelmann, S, Graham, IR, Harris, JD   +6 more
core  

Evidence based diabetology : strategies to prevent macrovascular disease and to reduce mortality [PDF]

, 2006
Diabetes mellitus (DM) is the most common metabolic disease worldwide and the number of newly diagnosed cases is increasing. DM is strongly associated with a number of devastating chronic late complications, including retinopathy, nephropathy and ...
Allemann, Sabin Liliane
core   +1 more source

Evidence that an APOE ε4 'double whammy' increases risk for Alzheimer's disease

BMC Medicine, 2012
Temporal lobe epilepsy (TLE) is associated with some of the same neuropathological features as those reported for early stages of typical Alzheimer's disease (AD). The APOE ε4 allele is associated with a gene-dose-dependent increase in AD risk and in the
Caesar Ina, Gandy Sam
doaj   +1 more source

Apolipoprotein A-I mimetics [PDF]

, 2014
PURPOSE OF REVIEW: To summarize recent publications in the field of apolipoprotein mimetics. RECENT FINDINGS: Apolipoprotein mimetic peptides continue to show efficacy in a number of animal models of disease and demonstrate properties that make them ...
Navab, Mohamad, Anantharamaiah, Gattadahalli M, Fogelman, Alan M, Reddy, Srinivasa T   +3 more
core   +1 more source

Dual Functions of Dietary Rubber Seed Oil Supplementation: Enriching N‐3 Polyunsaturated Fatty Acids and Enhancing Antioxidant Capacity in Pekin Ducks

Animal Research and One Health, EarlyView.
Dietary RSO supplementation improved growth performance, simultaneously enriched n‐3 polyunsaturated fatty acids (n‐3 PUFA), and enhanced antioxidant capacity in Pekin ducks, which suggested that RSO has the potential to be a novel n‐3 PUFA source and an antioxidant for Pekin ducks to generate animal functional foods.
Lei Zhuang, Yongbao Wu, Zitao Zhao, Junting Cao, Yanhong Guo, Zhanyue Wu, Qimeng Wang, Peilong Yang, Sen Wu, Zhiguo Wen, Shuisheng Hou   +10 more
wiley   +1 more source

HIV infection significantly reduces lipoprotein lipase which remains low after 6 months of antiretroviral therapy [PDF]

, 2008
Purpose of the study Fractional clearance rate of apolipoprotein B100-containing lipoproteins is reduced in HIV infection before and after antiretroviral (ARV) treatment [1].
LL Gathercole, M Boothby, S Das, Gathercole, L. L., McGee, K. C. (Kirsty Claire), Tomlinson, Jeremy, Shojaee-Moradie, F, Das, S. (Satyajit), Umpleby, AM, Tomlinson, J. W., Boothby, M., Umpleby, A.M., Shojaee-Moradie, F., F Shojaee-Moradie, JW Tomlinson, K McGee, Boothby, M, M Shahmanesh, Umpleby, A. M., Gathercole, LL, McGee, K, Das, S., Shahmanesh, Mohsen, Tomlinson, JW, Shahmanesh, M, AM Umpleby, Das, S   +26 more
core   +1 more source

Exploring the Roles of Tuna‐Associated Acinetobacter sp. YFT067: Implications for Host Health and Metabolism

Animal Research and One Health, EarlyView.
This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou, Hai Huang, Qiongyao Fu, Zhiyuan Lu, Zhiqiang Guo   +4 more
wiley   +1 more source

Elevated apolipoprotein(A) levels in cancer patients

, 1989
Elevated plasma lipoprotein(a) has been associated with an increased risk of cardiovascular disease. We report a significant elevation of total plasma apolipoprotein(a) levels in cancer patients compared with hospitalized control patients and normal ...
Dyne, Marlen, Mountford, Carolyn E., Wright, Lesley C., Tattersall, Martin H. N., Sullivan, David R., Muller, Mark   +5 more
core   +1 more source