Results 1 to 10 of about 1,201,601 (261)

Overexpression of SCAP inhibits autophagy and promotes lipid accumulation in vascular smooth muscle cells

Di-san junyi daxue xuebao, 2022
Objective To determine the effect of sterol regulatory element binding proteins cleavage activating protein (SCAP) on foam cell formation in vascular smooth muscle cells (VSMCs). Methods LV-SCAP were constructed with LV-SCAP, and LV-Control group served
RAO Yuhan, LI Danyang, HOU Xiaoli, YAO Yincheng, SU Yu   +4 more
doaj   +1 more source

First Case Report of Arrhythmogenic Right Ventricular Cardiomyopathy Showing Refractory Ventricular Tachycardia Induced by Thyroid Storm due to Graves’ Disease

Case Reports in Endocrinology, 2022
A 48-year-old man who was diagnosed with arrhythmogenic right ventricular cardiomyopathy (ARVC) due to a plakophilin 2 gene mutation developed acute both-sided heart failure with rapid atrial fibrillation and was hospitalized.
Masaki Matsubara, Tomohiro Tanaka, Akinori Wakamiya, Tamiko Tamanaha, Hisashi Makino, Tomonori Tanei, Takeshi Aiba, Kengo Kusano, Kiminori Hosoda   +8 more
doaj   +1 more source

Cholesterol metabolism is altered in Rett syndrome: A study on plasma and primary cultured fibroblasts derived from patients [PDF]

, 2014
Rett (RTT) syndrome is a severe neurological disorder that affects almost exclusively females. Several detectable mutations in the X-linked methyl-CpG-binding protein 2 gene (MECP2) are responsible for the onset of the disease.
Di Tunno, Ilenia, Hayek, Joussef, Pallottini, Valentina, Segatto, Marco, Sticozzi, Claudia, Trapani, Laura, Valacchi, Giuseppe   +6 more
core   +12 more sources

Effects of age, gender, and menopausal status on plasma low density lipoprotein cholesterol and apolipoprotein B levels in the Framingham Offspring Study.

Journal of Lipid Research, 1994
Plasma low density lipoprotein (LDL) cholesterol, non-high density lipoprotein (HDL) cholesterol, and apolipoprotein (apo) B, the major protein constituent of LDL, were measured in 1,533 men (mean age 49 +/- 10 years) and 1,597 women (mean age 49 +/- 10 ...
E J Schaefer, S Lamon-Fava, S D Cohn, M M Schaefer, J M Ordovas, W P Castelli, P W Wilson   +6 more
doaj   +1 more source

Factors associated with low and elevated plasma high density lipoprotein cholesterol and apolipoprotein A-I levels in the Framingham Offspring Study.

Journal of Lipid Research, 1994
A decreased high density lipoprotein (HDL) cholesterol level (< 35 mg/dl) has been shown to be a significant independent risk factor for coronary heart disease (CHD).
E J Schaefer, S Lamon-Fava, J M Ordovas, S D Cohn, M M Schaefer, W P Castelli, P W Wilson   +6 more
doaj   +1 more source

Efficacy of visceral fat estimation by dual bioelectrical impedance analysis in detecting cardiovascular risk factors in patients with type 2 diabetes

Cardiovascular Diabetology, 2019
Background Visceral fat area (VFA) is a good surrogate marker of obesity-related disorders, such as hypertension, dyslipidemia and glucose intolerance.
Yoko Omura-Ohata, Cheol Son, Hisashi Makino, Ryo Koezuka, Mayu Tochiya, Tamiko Tamanaha, Ichiro Kishimoto, Kiminori Hosoda   +7 more
doaj   +1 more source

Reduction of circulating cholesterol and apolipoprotein levels during sepsis [PDF]

, 1999
Sepsis with multiple organ failure is frequently associated with a substantial decrease of cholesterol levels. This decrease of cholesterol is strongly associated with mortality suggesting a direct relation between inflammatory conditions and altered ...
Alvarez C, Chajek-Shaul T, Engelmann H, Ettinger WH, Ettinger WH, Ettinger WH, Feingold KR, Feingold KR, Flegel WA, Gouni I, Graham A, Greenberg AS, Grove RI, Grunfeld C, Hubsch AP, Ishibashi S, Kipp HA, Moran CS, Netea MG, Pacelli F, Pak YK, Read TE, Semb H, Stopeck AT, Van Gameren MM, Weinstock C, Wilson DE, Yokoyama K   +27 more
core   +1 more source

Simultaneous measurements of chylomicron lipolysis and remnant removal using a doubly labeled artificial lipid emulsion: studies in normolipidemic and hyperlipidemic subjects.

Journal of Lipid Research, 1994
An artificial chylomicron-like lipid emulsion doubly labeled with tri[(N)3H]oleoylglycerol ([3H]TO) and cholesteryl [1-14C]oleate ([14C]CO) was infused intravenously into human subjects with the purpose of simultaneously measuring the plasma ...
E R Nakandakare, S A Lottenberg, H C Oliveira, M C Bertolami, K S Vasconcelos, G Sperotto, E C Quintão   +6 more
doaj   +1 more source

Adipocyte JAK2 Regulates Hepatic Insulin Sensitivity Independently of Body Composition, Liver Lipid Content, and Hepatic Insulin Signaling. [PDF]

, 2017
Disruption of hepatocyte growth hormone (GH) signaling through disruption of Jak2 (JAK2L) leads to fatty liver. Previously, we demonstrated that development of fatty liver depends on adipocyte GH signaling.
Camporez, João Paulo G, Corbit, Kevin C, Deo, Rahul C, Edmunds, Lia R, Erion, Derek M, Jurczak, Michael J, Perry, Rachel J, Shulman, Gerald I, Tran, Jennifer L, Vera, Nicholas B, Weiss, Ethan J   +10 more
core   +1 more source

Utilization of different fatty acids for hepatic and biliary phosphatidylcholine formation and the effect of changes in phosphatidylcholine molecular species on biliary lipid secretion.

Journal of Lipid Research, 1991
Biliary cholesterol secretion is ordinarily tightly coupled to phosphatidylcholine (PC) secretion. Bile PCs are distinct in composition and predominantly composed of molecular species with 16:0 in the sn-1 position and 18:2 and 18:1 in the sn-2 position.
SJ Robins, JM Fasulo, VF Robins, GM Patton   +3 more
doaj   +1 more source