Results 1 to 10 of about 779,747 (305)

The Catalytic Domain of Neuropathy Target Esterase Influences Lipid Droplet Biogenesis and Lipid Metabolism in Human Neuroblastoma Cells

open access: yes, 2022
As an endoplasmic reticulum (ER)-anchored phospholipase, neuropathy target esterase (NTE) catalyzes the deacylation of lysophosphatidylcholine (LPC) and phosphatidylcholine (PC).
Yijun Wu   +11 more
core   +1 more source

Utilization of different fatty acids for hepatic and biliary phosphatidylcholine formation and the effect of changes in phosphatidylcholine molecular species on biliary lipid secretion.

open access: yesJournal of Lipid Research, 1991
Biliary cholesterol secretion is ordinarily tightly coupled to phosphatidylcholine (PC) secretion. Bile PCs are distinct in composition and predominantly composed of molecular species with 16:0 in the sn-1 position and 18:2 and 18:1 in the sn-2 position.
SJ Robins   +3 more
doaj   +1 more source

Lipid metabolism and HCV infection [PDF]

open access: yes, 2010
Chronic infection by hepatitis C virus (HCV) can lead to severe liver disease and is a global healthcare problem. The liver is highly metabolically active and one of its key functions is to control the balance of lipid throughout the body.
Boulant, Steeve   +7 more
core   +1 more source

Cholesteryl esters in lymph chylomicrons: contribution from high density lipoprotein transferred from plasma into intestinal lymph

open access: yesJournal of Lipid Research, 1993
Most of the cholesterol in intestinal chyle and chylomicrons is derived from plasma. Our aim was to determine how much plasma low density (LDL) and high density (HDL) lipoproteins contribute to the cholesterol in chyle and chylomicrons, and to examine ...
HC Oliveira   +3 more
doaj   +1 more source

Genetic variants in lipid metabolism are independently associated with multiple features of the metabolic syndrome [PDF]

open access: yes, 2011
Background Our objective was to find single nucleotide polymorphisms (SNPs), within transcriptional pathways of glucose and lipid metabolism, which are related to multiple features of the metabolic syndrome (MetS).
Boer, J.M.   +14 more
core   +1 more source

Changes in biliary lipid secretion during normal development and diurnal cycling in the rat

open access: yesJournal of Lipid Research, 1993
Biliary lipid secretion in conjunction with hepatic cholesterol synthesis was determined in normal male rats at 4, 5, 7, and 9 weeks of age, during a period of linear growth and a near fourfold increase in liver size.
SJ Robins   +3 more
doaj   +1 more source

Nonimmunochemical quantitation of mammalian apolipoprotein A-I in whole serum or plasma by nonreducing gel electrophoresis.

open access: yesJournal of Lipid Research, 1989
A rapid and convenient method for the quantitation of mammalian apoA-I has been developed. The method involves nonreducing sodium dodecyl sulfate gel electrophoresis and Coomassie blue staining, and takes advantage of the relative abundance of apoA-I in ...
D S France   +7 more
doaj   +1 more source

Metabolite profile of treatment-naive metabolic syndrome subjects in relation to cardiovascular disease risk

open access: yes, 2021
Metabolic syndrome (MetSyn) is an important risk factor for type 2 diabetes and cardiovascular diseases (CVD). This study aimed to find distinct plasma metabolite profiles between insulin-resistant and non-insulin resistant subjects with MetSyn and ...
Pieter F. de Groot   +29 more
core   +1 more source

Hepatic phosphatidylcholines: evidence for synthesis in the rat by extensive reutilization of endogenous acylglycerides.

open access: yesJournal of Lipid Research, 1994
Studies were performed to compare the extent of fatty acid incorporation into liver phosphatidylcholines (PCs) by acyl remodeling and by de novo synthesis.
G M Patton, J M Fasulo, S J Robins
doaj   +1 more source

Fat oxidation, fitness and skeletal muscle expression of oxidative/lipid metabolism genes in South Asians: implications for insulin resistance? [PDF]

open access: yes, 2010
<p><b>Background:</b> South Asians are more insulin resistant than Europeans, which cannot be fully explained by differences in adiposity. We investigated whether differences in oxidative capacity and capacity for fatty acid utilisation
Nita G Forouhi   +45 more
core   +1 more source

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