Results 11 to 20 of about 1,201,601 (261)

Peroxisomal dysfunctions cause lysosomal storage and axonal Kv1 channel redistribution in peripheral neuropathy [PDF]

, 2017
Impairment of peripheral nerve function is frequent in neurometabolic diseases, but mechanistically not well understood. Here, we report a novel disease mechanism and the finding that glial lipid metabolism is critical for axon function, independent of ...
Asadollahi, Ebrahim, Baes, Myriam, Blanz, Judith, Brügger, Britta, de Hoz, Livia, Kassmann, Celia Michèle, Kleinecke, Sandra, Kungl, Theresa, Lüchtenborg, Christian, McGonigal, Rhona, Möbius, Wiebke, Naseri, Kobra, Nave, Klaus-Armin, Quintes, Susanne, Richert, Sarah, Sachsenheimer, Timo, Sereda, Michael W., Willison, Hugh   +17 more
core   +3 more sources

Cholesteryl esters in lymph chylomicrons: contribution from high density lipoprotein transferred from plasma into intestinal lymph

Journal of Lipid Research, 1993
Most of the cholesterol in intestinal chyle and chylomicrons is derived from plasma. Our aim was to determine how much plasma low density (LDL) and high density (HDL) lipoproteins contribute to the cholesterol in chyle and chylomicrons, and to examine ...
HC Oliveira, K Nilausen, H Meinertz, EC Quintão   +3 more
doaj   +1 more source

Alterations of intestinal lipoprotein metabolism in diabetes mellitus and metabolic syndrome [PDF]

, 2015
Diabetes and metabolic syndrome are associated with abnormal postprandial lipoprotein metabolism, with a significant delay in the clearance of many lipid parameters, including triglycerides and chylomicrons.
ARCA, Marcello
core   +1 more source

A Role of the Bile Salt Receptor FXR in Atherosclerosis [PDF]

, 2010
This study reviews current insights into the role of bile salts and bile salt receptors on the progression and regression of atherosclerosis. Bile salts have emerged as important modifiers of lipid and energy metabolism.
Groen, A.K., Hageman, J., Herrema, H.J., Kuipers, F.   +3 more
core   +3 more sources

Changes in biliary lipid secretion during normal development and diurnal cycling in the rat

Journal of Lipid Research, 1993
Biliary lipid secretion in conjunction with hepatic cholesterol synthesis was determined in normal male rats at 4, 5, 7, and 9 weeks of age, during a period of linear growth and a near fourfold increase in liver size.
SJ Robins, JM Fasulo, PD Lessard, GM Patton   +3 more
doaj   +1 more source

Nonimmunochemical quantitation of mammalian apolipoprotein A-I in whole serum or plasma by nonreducing gel electrophoresis.

Journal of Lipid Research, 1989
A rapid and convenient method for the quantitation of mammalian apoA-I has been developed. The method involves nonreducing sodium dodecyl sulfate gel electrophoresis and Coomassie blue staining, and takes advantage of the relative abundance of apoA-I in ...
D S France, T E Hughes, R Miserendino, J A Spirito, J Babiak, J B Eskesen, C Tapparelli, J R Paterniti, Jr   +7 more
doaj   +1 more source

Hepatic phosphatidylcholines: evidence for synthesis in the rat by extensive reutilization of endogenous acylglycerides.

Journal of Lipid Research, 1994
Studies were performed to compare the extent of fatty acid incorporation into liver phosphatidylcholines (PCs) by acyl remodeling and by de novo synthesis.
G M Patton, J M Fasulo, S J Robins
doaj   +1 more source

Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. [PDF]

, 2010
Hepatitis C virus (HCV) infection is closely tied to the lipid metabolism of liver cells. Here we identify the triglyceride-synthesizing enzyme diacylglycerol acyltransferase-1 (DGAT1) as a key host factor for HCV infection.
Carpentier, Arnaud, Farese, Robert V, Harris, Charles, Herker, Eva, Hernandez, Céline, Kaehlcke, Katrin, Ott, Melanie, Rosenberg, Arielle R   +7 more
core   +1 more source

miRNAs link metabolic reprogramming to oncogenesis [PDF]

, 2013
The most profound biochemical phenotype of cancer cells is their ability to metabolize glucose to lactate, even under aerobic conditions. This alternative metabolic circuitry is sufficient to support the biosynthetic and energy requirements for cancer ...
Hatziapostolou, M, Iliopoulos, D, Polytarchou, C   +2 more
core   +1 more source

Transcriptome analyses reveal reduced hepatic lipid synthesis and accumulation in more feed efficient beef cattle [PDF]

, 2018
peer-reviewedThe genetic mechanisms controlling residual feed intake (RFI) in beef cattle are still largely unknown. Here we performed whole transcriptome analyses to identify differentially expressed (DE) genes and their functional roles in liver ...
Fitzsimmons, Carolyn, Keogh, Kate, Li, Changxi, Mukiibi, Robert, Stothard, Paul, Vinsky, Michael, Waters, Sinead M.   +6 more
core   +3 more sources